Blockade of Nuclear β ‐Catenin Signaling via Direct Targeting of RanBP3 with NU2058 Induces Cell Senescence to Suppress Colorectal Tumorigenesis

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2021) Hyuna Sung et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Maprotiline Suppresses Cholesterol Biosynthesis and Hepatocellular Carcinoma Progression Through Direct Targeting of CRABP1

(2021) Cancan Zheng et al.   Frontiers in Pharmacology

Targeting PFKL with penfluridol inhibits glycolysis and suppresses esophageal cancer tumorigenesis in an AMPK/FOXO3a/BIM-dependent manner

(2021) Cancan Zheng et al.   Acta Pharmaceutica Sinica B

Drug resistance in colorectal cancer: An epigenetic overview

(2021) Maochao Luo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Targeting PP2A with lomitapide suppresses colorectal tumorigenesis through the activation of AMPK/Beclin1-mediated autophagy

(2021) Qian Zuo et al.   CANCER LETTERS

Single-Cell Analyses Inform Mechanisms of Myeloid-Targeted Therapies in Colon Cancer

(2020) Lei Zhang et al.   CELL

Lineage-dependent gene expression programs influence the immune landscape of colorectal cancer

(2020) Hae-Ock Lee et al.   NATURE GENETICS

Echinatin suppresses esophageal cancer tumor growth and invasion through inducing AKT/mTOR-dependent autophagy and apoptosis

(2020) Pan Hong et al.   Cell Death & Disease

Direct Targeting of CREB1 with Imperatorin Inhibits TGF β 2‐ERK Signaling to Suppress Esophageal Cancer Metastasis

(2020) Wen Wen Xu et al.   Advanced Science

TRAF6 inhibits colorectal cancer metastasis through regulating selective autophagic CTNNB1/β-catenin degradation and is targeted for GSK3B/GSK3β-mediated phosphorylation and degradation

(2019) Hua Wu et al.   Autophagy

Wnt/β‐catenin/RAS signaling mediates age‐related renal fibrosis and is associated with mitochondrial dysfunction

(2019) Jinhua Miao et al.   AGING CELL

Adefovir dipivoxil sensitizes colon cancer cells to vemurafenib by disrupting the KCTD12-CDK1 interaction

(2019) Jie Yang et al.   CANCER LETTERS

Cellular Senescence and the Immune System in Cancer

(2019) Luis I. Prieto et al.   GERONTOLOGY

Expansion and Cell-Cycle Arrest: Common Denominators of Cellular Senescence

(2019) Mikolaj Ogrodnik et al.   TRENDS IN BIOCHEMICAL SCIENCES

Interleukin4Rα (IL4Rα) and IL13Rα1 Are Associated with the Progress of Renal Cell Carcinoma through Janus Kinase 2 (JAK2)/Forkhead Box O3 (FOXO3) Pathways

(2019) Mi-Ae Kang et al.   Cancers

A Map of Protein-Metabolite Interactions Reveals Principles of Chemical Communication

(2018) Ilaria Piazza et al.   CELL

Mechanisms and functions of cellular senescence

(2018) Nicolás Herranz et al.   JOURNAL OF CLINICAL INVESTIGATION

Liensinine perchlorate inhibits colorectal cancer tumorigenesis by inducing mitochondrial dysfunction and apoptosis

(2018) Yang Wang et al.   Food & Function

Therapeutic potential of targeting the Wnt/β-catenin signaling pathway in colorectal cancer

(2018) Xiaofei Cheng et al.   BIOMEDICINE & PHARMACOTHERAPY

Senescent cells: an emerging target for diseases of ageing

(2017) Bennett G. Childs et al.   NATURE REVIEWS DRUG DISCOVERY

MicroRNA-377 suppresses initiation and progression of esophageal cancer by inhibiting CD133 and VEGF

(2017) B Li et al.   ONCOGENE

An Assay Using Localized Surface Plasmon Resonance and Gold Nanorods Functionalized with Aptamers to Sense the Cytochrome-c Released from Apoptotic Cancer Cells for Anti-Cancer Drug Effect Determination

(2017) Jacky Loo et al.   Micromachines

RanBP3 Regulates Melanoma Cell Proliferation via Selective Control of Nuclear Export

(2016) Gaurav Pathria et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Wnt signaling in cancer

(2016) T Zhan et al.   ONCOGENE

Irinotecan, a key chemotherapeutic drug for metastatic colorectal cancer

(2015) Ken-ichi Fujita   WORLD JOURNAL OF GASTROENTEROLOGY

Improved vectors and genome-wide libraries for CRISPR screening

(2014) Neville E Sanjana et al.   NATURE METHODS

Comprehensive molecular characterization of human colon and rectal cancer

(2012)   NATURE

Wnt signaling and senescence: A tug of war in early neoplasia?

(2010) Peter D. Adams et al.   CANCER BIOLOGY & THERAPY

The essence of senescence

(2010) T. Kuilman et al.   GENES & DEVELOPMENT

The kinase inhibitor O6-cyclohexylmethylguanine (NU2058) potentiates the cytotoxicity of cisplatin by mechanisms that are independent of its effect upon CDK2

(2009) Luke R.E. Harrison et al.   BIOCHEMICAL PHARMACOLOGY