Maprotiline Suppresses Cholesterol Biosynthesis and Hepatocellular Carcinoma Progression Through Direct Targeting of CRABP1

EZH2 inhibitor GSK343 inhibits sepsis‑induced intestinal disorders

(2021) Dongyou Yue et al.   Experimental and Therapeutic Medicine

Echinatin suppresses esophageal cancer tumor growth and invasion through inducing AKT/mTOR-dependent autophagy and apoptosis

(2020) Pan Hong et al.   Cell Death & Disease

Direct Targeting of CREB1 with Imperatorin Inhibits TGF β 2‐ERK Signaling to Suppress Esophageal Cancer Metastasis

(2020) Wen Wen Xu et al.   Advanced Science

Cholesterol Biosynthesis Influences Subtype Specificity and Plasticity in Pancreas Cancer

(2020) Sita Kugel et al.   CANCER CELL

Rspo1/Rspo3-LGR4 signaling inhibits hepatic cholesterol synthesis through the AMPKα-SREBP2 pathway

(2020) Shiying Liu et al.   FASEB JOURNAL

Cholesterol metabolism in drug‑resistant cancer (Review)

(2020) Aiwen Yan et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Oncofetal HLF transactivates c-Jun to promote hepatocellular carcinoma development and sorafenib resistance

(2019) Dai-Min Xiang et al.   GUT

Cholesterol biosynthesis supports the growth of hepatocarcinoma lesions depleted of fatty acid synthase in mice and humans

(2019) Li Che et al.   GUT

Celecoxib inhibits the epithelial-to-mesenchymal transition in bladder cancer via the miRNA-145/TGFBR2/Smad3 axis

(2019) Xiaoqiang Liu et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

β-Catenin Activation Promotes Immune Escape and Resistance to Anti–PD-1 Therapy in Hepatocellular Carcinoma

(2019) Marina Ruiz de Galarreta et al.   Cancer Discovery

A new regulatory mechanism for Raf kinase activation, retinoic acid-bound Crabp1

(2019) Sung Wook Park et al.   Scientific Reports

Ursolic Acid Suppresses Cholesterol Biosynthesis and Exerts Anti-Cancer Effects in Hepatocellular Carcinoma Cells

(2019) Geon-Hee Kim et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Even Cancer Cells Watch Their Cholesterol!

(2019) Romain Riscal et al.   MOLECULAR CELL

LncRNA NR2F1-AS1 regulates hepatocellular carcinoma oxaliplatin resistance by targeting ABCC1 via miR-363

(2018) Hai Huang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Exosomal microRNA-32-5p induces multidrug resistance in hepatocellular carcinoma via the PI3K/Akt pathway

(2018) Xiao Fu et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Celecoxib suppresses proliferation and metastasis of pancreatic cancer cells by down-regulating STAT3 / NF-kB and L1CAM activities

(2018) Chaohui Zuo et al.   PANCREATOLOGY

CD24 regulates sorafenib resistance via activating autophagy in hepatocellular carcinoma

(2018) Shuai Lu et al.   Cell Death & Disease

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Synephrine Hydrochloride Suppresses Esophageal Cancer Tumor Growth and Metastatic Potential through Inhibition of Galectin-3-AKT/ERK Signaling

(2018) Wen Wen Xu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Maprotiline Prevents Monocrotaline-Induced Pulmonary Arterial Hypertension in Rats

(2018) Yi Tong et al.   Frontiers in Pharmacology

Emodin Sensitizes Hepatocellular Carcinoma Cells to the Anti-Cancer Effect of Sorafenib through Suppression of Cholesterol Metabolism

(2018) Young-Seon Kim et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Celecoxib in breast cancer prevention and therapy

(2018) Jieqing Li et al.   Cancer Management and Research

Cellular Retinoic Acid–Binding Protein 1 Modulates Stem Cell Proliferation to Affect Learning and Memory in Male Mice

(2017) Yu-Lung Lin et al.   ENDOCRINOLOGY

FGF19/FGFR4 signaling contributes to the resistance of hepatocellular carcinoma to sorafenib

(2017) Lixia Gao et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

MicroRNA-377 suppresses initiation and progression of esophageal cancer by inhibiting CD133 and VEGF

(2017) B Li et al.   ONCOGENE

All trans-retinoic acid analogs promote cancer cell apoptosis through non-genomic Crabp1 mediating ERK1/2 phosphorylation

(2016) Shawna D. Persaud et al.   Scientific Reports

Analysis of the anti-allodynic effects of combination of a synthetic cannabinoid and a selective noradrenaline re-uptake inhibitor in nerve injury-induced neuropathic mice

(2015) O. Gunduz et al.   EUROPEAN JOURNAL OF PAIN

CRABP1 provides high malignancy of transformed mesenchymal cells and contributes to the pathogenesis of mesenchymal and neuroendocrine tumors

(2014) Yaroslav Kainov et al.   CELL CYCLE

Cholesterol and Cancer, in the Balance

(2014) S. Silvente-Poirot et al.   SCIENCE

Cellular retinoic acid binding protein I mediates rapid non-canonical activation of ERK1/2 by all-trans retinoic acid

(2012) Shawna D. Persaud et al.   CELLULAR SIGNALLING

AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading

(2009) Oleg Trott et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY