Potential benefits of metformin and pioglitazone combination therapy via gut microbiota and metabolites in high-fat diet-fed mice

Assessing the validity of plasma phospholipid fatty acids as biomarkers of dairy fat intake using data from a randomized controlled intervention trial

(2022) Hilary J Bethancourt et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

San-Huang-Yi-Shen Capsule Ameliorates Diabetic Nephropathy in Rats Through Modulating the Gut Microbiota and Overall Metabolism

(2022) Xiuhai Su et al.   Frontiers in Pharmacology

Bacillus subtilis inhibits intestinal inflammation and oxidative stress by regulating gut flora and related metabolites in laying hens

(2022) X.Y. Zou et al.   Animal

Tectorigenin ameliorated high-fat diet-induced nonalcoholic fatty liver disease through anti-inflammation and modulating gut microbiota in mice

(2022) Ruiqian Duan et al.   FOOD AND CHEMICAL TOXICOLOGY

Tyrosol Ameliorates the Symptoms of Obesity, Promotes Adipose Thermogenesis, and Modulates the Composition of Gut Microbiota in HFD Fed Mice

(2022) Xiaoping Li et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Maternal Dietary Betaine Prevents High-Fat Diet-Induced Metabolic Disorders and Gut Microbiota Alterations in Mouse Dams and Offspring From Young to Adult

(2022) Jieying Liu et al.   Frontiers in Microbiology

Adipocyte-derived PGE2 is required for intermittent fasting–induced Treg proliferation and improvement of insulin sensitivity

(2022) Chunqing Wang et al.   JCI Insight

Ban-Lan-Gen Granule Alleviates Dextran Sulfate Sodium-Induced Chronic Relapsing Colitis in Mice via Regulating Gut Microbiota and Restoring Gut SCFA Derived-GLP-1 Production

(2022) Jiao Peng et al.   Journal of Inflammation Research

Beneficial Actions of Essential Fatty Acids in Streptozotocin-Induced Type 1 Diabetes Mellitus

(2022) Junhui Shen et al.   Frontiers in Nutrition

Identification of Crucial Amino Acid Residues for Antimicrobial Activity of Angiogenin 4 and Its Modulation of Gut Microbiota in Mice

(2022) Mst. Farzana Sultana et al.   Frontiers in Microbiology

High animal protein diet and gut microbiota in human health

(2021) Jie Cai et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Metformin Affects Gut Microbiome Composition and Function and Circulating Short-Chain Fatty Acids: A Randomized Trial

(2021) Noel T. Mueller et al.   DIABETES CARE

IDF Diabetes Atlas: Global, regional and country-level diabetes prevalence estimates for 2021 and projections for 2045

(2021) Hong Sun et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Modulation of Insulin Resistance, Dyslipidemia and Serum Metabolome in iNOS Knockout Mice following Treatment with Nitrite, Metformin, Pioglitazone, and a Combination of Ampicillin and Neomycin

(2021) Hobby Aggarwal et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The metabolic regulation of Fuzhuan brick tea in high-fat diet-induced obese mice and the potential contribution of gut microbiota

(2021) Dongmin Liu et al.   Food & Function

Si-Wu-Tang ameliorates fibrotic liver injury via modulating intestinal microbiota and bile acid homeostasis

(2021) Xiaoyong Xue et al.   Chinese Medicine

Metformin Exerts Anti-inflammatory and Mucus Barrier Protective Effects by Enriching Akkermansia muciniphila in Mice With Ulcerative Colitis

(2021) Haoran Ke et al.   Frontiers in Pharmacology

Metformin reduces aging-related leaky gut and improves cognitive function by beneficially modulating gut microbiome/goblet cell/mucin axis

(2020) Shokouh Ahmadi et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Citrus polymethoxyflavones attenuate metabolic syndrome by regulating gut microbiome and amino acid metabolism

(2020) Su-Ling Zeng et al.   Science Advances

Role of gut microbiota in type 2 diabetes pathophysiology

(2020) Manoj Gurung et al.   EBioMedicine

9. Pharmacologic Approaches to Glycemic Treatment: Standards of Medical Care in Diabetes—2021

(2020)   DIABETES CARE

Gut microbiota-derived metabolites as central regulators in metabolic disorders

(2020) Allison Agus et al.   GUT

Identification of gut microbiota and microbial metabolites regulated by an antimicrobial peptide lipocalin 2 in high fat diet-induced obesity

(2020) Xiaoxue Qiu et al.   INTERNATIONAL JOURNAL OF OBESITY

Untargeted metabolomics characteristics of nonobese nonalcoholic fatty liver disease induced by high-temperature-processed feed in Sprague-Dawley rats

(2020) Li-Jun Xue et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Defining the role of Parasutterella, a previously uncharacterized member of the core gut microbiota

(2019) Tingting Ju et al.   ISME Journal

The role of short-chain fatty acids in microbiota–gut–brain communication

(2019) Boushra Dalile et al.   Nature Reviews Gastroenterology & Hepatology

Dietary fructose-induced gut dysbiosis promotes mouse hippocampal neuroinflammation: a benefit of short-chain fatty acids

(2019) Jian-Mei Li et al.   Microbiome

Changes of gut microbiota during silybin mediated treatment of high‐fat diet‐induced nonalcoholic fatty liver diseasein mouse

(2019) Xiuxia Li et al.   HEPATOLOGY RESEARCH

Diabetes and branched-chain amino acids: What is the link?

(2018) Zachary Bloomgarden   Journal of Diabetes

Probiotics improve gut microbiota dysbiosis in obese mice fed a high-fat or high-sucrose diet

(2018) Cheng Kong et al.   NUTRITION

Suppression of adipocyte differentiation and lipid accumulation by stearidonic acid (SDA) in 3T3-L1 cells

(2017) Yueru Li et al.   Lipids in Health and Disease

Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug

(2017) Hao Wu et al.   NATURE MEDICINE

Global aetiology and epidemiology of type 2 diabetes mellitus and its complications

(2017) Yan Zheng et al.   Nature Reviews Endocrinology

Protective effect of Sophoraflavanone G on streptozotocin (STZ)-induced inflammation in diabetic rats

(2016) Hanqing Wang et al.   BIOMEDICINE & PHARMACOTHERAPY

Metformin and the gastrointestinal tract

(2016) Laura J. McCreight et al.   DIABETOLOGIA

Response of gut microbiota and inflammatory status to bitter melon (Momordica charantia L.) in high fat diet induced obese rats

(2016) Juan Bai et al.   JOURNAL OF ETHNOPHARMACOLOGY

Lipoxin A4 Attenuates Obesity-Induced Adipose Inflammation and Associated Liver and Kidney Disease

(2015) Emma Börgeson et al.   Cell Metabolism

Crosstalk between Gut Microbiota and Dietary Lipids Aggravates WAT Inflammation through TLR Signaling

(2015) Robert Caesar et al.   Cell Metabolism

PPARγ signaling and metabolism: the good, the bad and the future

(2013) Maryam Ahmadian et al.   NATURE MEDICINE

A metagenome-wide association study of gut microbiota in type 2 diabetes

(2012) Junjie Qin et al.   NATURE

Quality-filtering vastly improves diversity estimates from Illumina amplicon sequencing

(2012) Nicholas A Bokulich et al.   NATURE METHODS

Metagenomic biomarker discovery and explanation

(2011) Nicola Segata et al.   GENOME BIOLOGY

Pioglitazone reduces systematic inflammation and improves mortality in apolipoprotein E knockout mice with sepsis

(2008) Go Haraguchi et al.   INTENSIVE CARE MEDICINE