Examining potential mechanisms of testicular fibrosis in Klinefelter Syndrome: A review of current understanding

To graft or not to graft? Intratesticular xenografting of (pre)pubertal testicular tissue from Klinefelter patients as potential ex vivo model to study testicular fibrosis

(2022) M Willems et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Germ cell loss in Klinefelter syndrome: When and why?

(2020) Margo Willems et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS

Integration and reanalysis of transcriptomics and methylomics data derived from blood and testis tissue of men with 47, XXY Klinefelter syndrome indicates the primary involvement of Sertoli cells in the testicular pathogenesis

(2020) Sofia B. Winge et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS

Characterization of the stem cell niche components within the seminiferous tubules in testicular biopsies of Klinefelter patients

(2020) Dorien Van Saen et al.   FERTILITY AND STERILITY

Testicular immune cells and vasculature in Klinefelter syndrome from childhood up to adulthood

(2020) Margo Willems et al.   HUMAN REPRODUCTION

Infertility considerations in klinefelter syndrome: From origin to management

(2020) Nicholas A. Deebel et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

High-resolution analysis of germ cells from men with sex chromosomal aneuploidies reveals normal transcriptome but impaired imprinting

(2019) Sandra Laurentino et al.   Clinical Epigenetics

Blood Testis Barrier and Somatic Cells Impairment in a Series of 35 Adult Klinefelter Syndrome Patients

(2019) Giudice et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Age-related presence of spermatogonia in patients with Klinefelter syndrome: a systematic review and meta-analysis

(2019) Nicholas A Deebel et al.   HUMAN REPRODUCTION UPDATE

When does germ cell loss and fibrosis occur in patients with Klinefelter syndrome?

(2018) D Van Saen et al.   HUMAN REPRODUCTION

Organ and tissue fibrosis: Molecular signals, cellular mechanisms and translational implications

(2018) Ralf Weiskirchen et al.   MOLECULAR ASPECTS OF MEDICINE

Transcriptome analysis of the adult human Klinefelter testis and cellularity-matched controls reveals disturbed differentiation of Sertoli- and Leydig cells

(2018) Sofia Boeg Winge et al.   Cell Death & Disease

Transcriptome profiling of fetal Klinefelter testis tissue reveals a possible involvement of long non-coding RNAs in gonocyte maturation

(2017) Sofia B Winge et al.   HUMAN MOLECULAR GENETICS

Sperm recovery and ICSI outcomes in Klinefelter syndrome: a systematic review and meta-analysis

(2017) Giovanni Corona et al.   HUMAN REPRODUCTION UPDATE

Testis Transcriptome Modulation in Klinefelter Patients with Hypospermatogenesis

(2017) Marco D’Aurora et al.   Scientific Reports

The 2016 revision of the World Health Organization classification of lymphoid neoplasms

(2016) S. H. Swerdlow et al.   BLOOD

Deregulation of sertoli and leydig cells function in patients with klinefelter syndrome as evidenced by testis transcriptome analysis

(2015) Marco D’Aurora et al.   BMC GENOMICS

Mechanisms of fibrosis: therapeutic translation for fibrotic disease

(2012) Thomas A Wynn et al.   NATURE MEDICINE

Cellular and molecular mechanisms of intestinal fibrosis

(2012) Silvia Speca   WORLD JOURNAL OF GASTROENTEROLOGY

Clinical and hormonal status of infants with nonmosaic XXY karyotype

(2011) Najiba Lahlou et al.   ACTA PAEDIATRICA