Article
Materials Science, Multidisciplinary
Xiaohui Yang, Xixia Liu, Fangshen Xu, Shunxian Ji, Yuchao Sun, Zhaojun Song, Jie Song, Yulian Wu, Jun Yin
Summary: In this study, degradable poly(lactic-co-glycolic acid) nerve guide conduits with microgroove or smooth inner surface were fabricated using a phase inversion-based dry-jet wet spinning method for the regeneration of recurrent laryngeal nerve (RLN). The results showed that the conduit with microgroove structure exhibited better cellular behavior and the ability to promote RLN regeneration in an animal model. This study contributes to the design and application of nerve guide conduits and tissue engineering in RLN injury repair.
MATERIALS & DESIGN
(2022)
Article
Polymer Science
Maria Herrero-Herrero, Jose Antonio Gomez-Tejedor, Ana Valles-Lluch
Summary: Tailored membranes with a fiber diameter of 1.8 μm were electrospun from PLGA and PCLGA solutions by adjusting electrospinning and polymer solution parameters. PCLGA, with its amorphous morphology, required the addition of a salt to increase conductivity for successful electrospinning, presenting notable difficulties due to its structure. Interestingly, PCLGA, with a higher glycolic acid molar fraction, could be successfully electrospun, a feat not previously reported.
Article
Chemistry, Multidisciplinary
Rong Wang, Xiaojie Sun, Lanlan Chen, Wenbin Liang
Summary: In this study, biodegradable blends of PGA and PBAT with in situ compatibilization using MDI were prepared. The addition of PBAT was found to increase the complex viscosity and storage modulus of the blends, leading to improved compatibility and impact strength. The morphology of the dispersed phase evolved from spherical structure to in situ microfiber, enhancing interfacial adhesion and improving toughness.
Review
Engineering, Biomedical
Duoyi Zhao, Tongtong Zhu, Jie Li, Liguo Cui, Zhiyu Zhang, Xiuli Zhuang, Jianxun Ding
Summary: This article comprehensively reviews the research and applications of artificial bone-substitute materials based on PLGA and its composites, discussing their potential and challenges in bone regeneration.
BIOACTIVE MATERIALS
(2021)
Article
Polymer Science
Yi-Pin Chen, Tsia-Shu Lo, Yu-Ting Lin, Yu-Han Chien, Chia-Jung Lu, Shih-Jung Liu
Summary: Degradable drug-eluting prolapse mats were developed using solution-extrusion 3D printing and coaxial electrospinning techniques. The mats, composed of PCL mesh and PLGA nanofibers with incorporated drugs, exhibited comparable mechanical properties to commercial non-degradable polypropylene knitted meshes for POP repair. In vitro release studies showed sustained release of drugs from the membranes, with no adverse effects observed in animal tests, indicating potential for POP applications.
Article
Polymer Science
Yongxuan Chen, Kefeng Xie, Yucheng He, Wenbing Hu
Summary: The study reports the isothermal crystallization kinetics of poly(glycolic acid) (PGA) and compares it to poly((L)-lactic acid) (PLLA). It was found that PGA generally crystallizes more quickly than PLLA, which is attributed to the smaller hydrogen side group of PGA and the differences in molecular mobility and packing between the two polymers.
Article
Materials Science, Multidisciplinary
Eva M. M. Eger, Seema Agarwal
Summary: This study focuses on the characterization and reprocessing ability of PLGA in the form of dynamic covalent networks. The synthesized networks with dynamic bonding and debonding have enhanced thermomechanical properties and maintain the potential for thermal reprocessing and recycling like thermoplastics.
ACS APPLIED POLYMER MATERIALS
(2023)
Article
Pharmacology & Pharmacy
Kostas Tsachouridis, Evi Christodoulou, Alexandra Zamboulis, Anna Michopoulou, Panagiotis Barmpalexis, Dimitrios N. Bikiaris
Summary: The present study evaluates the use of novel copolymers for the preparation of paclitaxel loaded nanoparticles. The copolymers showed good enzymatic hydrolysis and low cytotoxicity, making them suitable drug matrix/carriers. The prepared nanoparticles exhibited small size, good drug loading and encapsulation efficiency. In vitro dissolution analysis showed biphasic drug dissolution profiles.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Han-Seung Ko, Sangwoon Lee, Doyoung Lee, Jae Young Jho
Summary: By introducing PGA fibers and HA into PLA composites and modifying HA, the tensile and flexural strength of PLA/HA-g-PLA composites were improved, along with enhancing the interfacial adhesion between HA and the PLA matrix.
Article
Pharmacology & Pharmacy
Wan-Yi Liu, Yun-Shan Hsieh, Yu-Tse Wu
Summary: This study aimed to develop a nanoparticle formulation for the oral delivery of beta-carotene. The results showed that the formulation significantly enhanced the release and intestinal permeability of the drug, suggesting its potential for oral administration.
Article
Polymer Science
Alastair Little, Alan M. Wemyss, David M. Haddleton, Bowen Tan, Zhaoyang Sun, Yang Ji, Chaoying Wan
Summary: The study investigates the effects of various reaction conditions on the synthesis of PLGA25, showing how factors such as reaction temperature, initiator concentration, and catalyst concentration impact the molecular weight, monomer conversion, and thermal properties.
Article
Chemistry, Multidisciplinary
Yiye Lu, Geoffrey W. Coates
Summary: Poly(lactic-co-glycolic acid) (PLGA) is widely used in various biomedical applications due to its biodegradability and biocompatibility. This study successfully developed a method to synthesize syndioenriched, alternating PLGA from racemic methyl-glycolide (rac-MeG), and confirmed the high degree of alternation of the comonomer sequence and moderate syndiotacticity within the polymer backbone stereoconfiguration through NMR investigations.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Article
Chemistry, Multidisciplinary
Taegyun Yeo, Young-Gwang Ko, Eun Jin Kim, Oh Kyoung Kwon, Ho Yun Chung, Oh Hyeong Kwon
Summary: 3D-printed PGA/HAp scaffolds demonstrate significant potential for promoting bone tissue regeneration with higher compressive strength and biodegradability. Clinical experiments show a higher rate of bone regeneration and bone density.
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
(2021)
Article
Engineering, Biomedical
Ramesh Duwa, Ram Hari Pokhrel, Asmita Banstola, Mahesh Pandit, Prakash Shrestha, Jee-Heon Jeong, Jae-Hoon Chang, Simmyung Yook
Summary: Bispecific nanoparticles enhance T cell cytotoxicity by targeting tumor-specific proteins and activating T cells to lyse tumor cells. The nanoparticles also activate dendritic cells and enhance T cell activation, leading to the inhibition of PD-L1 expressed cancer cells. In vivo experiments show that the nanoparticles significantly inhibit tumor growth and enhance intratumoral infiltration of CD4+ and CD8+ T cells, as well as tumor-infiltrated cytokines.
Article
Chemistry, Multidisciplinary
Yiye Lu, Geoffrey W. Coates
Summary: Poly(lactic-co-glycolic acid) (PLGA) is a biodegradable and biocompatible polymer used in biomedical applications. This study presents a method for synthesizing syndioenriched, alternating PLGA from racemic methyl-glycolide with the use of an optimized racemic aluminum catalyst. The resulting material has a high degree of alternation in copolymer sequence and moderate syndiotacticity, and is amorphous, making it suitable for drug complexation.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Article
Materials Science, Multidisciplinary
Tongyu Han, Haifeng Shi, Yigang Chen
Summary: In this study, a novel S-scheme system was built by combining CuO with BiVO4 to activate PMS for antibiotic degradation. The system exhibited excellent visible light absorption performance and remarkable charge separation ability, suggesting its potential application in enhancing PMS activation and purifying antibiotics in water.
JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
(2024)
Article
Materials Science, Multidisciplinary
Linlin Zhou, Tao Yang, Chunyu Guo, Kang Wang, Enhui Wang, Laipan Zhu, Hailong Wang, Sheng Cao, Kuo-Chih Chou, Xinmei Hou
Summary: Piezoelectric silicon carbide (SiC) has been considered for various applications due to its superior properties. However, its brittleness and unsatisfactory piezoelectric response have limited its use. In this study, PVDF/6H-SiC composite fiber films were fabricated and used for assembling high-performance energy harvesters and sensors. The results showed significant improvements in piezoelectric response and sensitivity compared to pure PVDF films. First-principles calculation and finite element analysis confirmed the effect of SiC nanoparticles on the composite film.
JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
(2024)
Article
Materials Science, Multidisciplinary
Y. F. An, X. P. Chen, L. Mei, P. Ren, D. Wei, W. Q. Cao
Summary: This study systematically investigates the precipitation sequence of Fe-28Mn-11Al-1C-5Ni austenitic low-density steel and its influence on mechanical properties. The results reveal the transformation pathway of kappa' -carbides and B2 particles under different aging conditions. This research is meaningful for guiding the design of new generation dual-nano precipitation austenitic lightweight steel.
JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
(2024)
Article
Materials Science, Multidisciplinary
Lei Yang, Tingkai Zhao, Abdul Jalil, Huijun Luo, Tao Jiang, Yuan Shu, Yazhou Yin, Weiyu Jia
Summary: In this study, a strategy utilizing oxygen vacancy concentration modulation was used to successfully grow semiconducting single-walled carbon nanotubes (s-SWCNTs) with narrow diameters. The Fe0.01Mg0.99O/CeO2(3) catalyst was employed to provide oxygen vacancies, allowing for selective etching of chemically active carbon nanotube caps during the growth process. The optimized conditions resulted in high purity s-SWCNTs with uniform diameters.
JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
(2024)
Letter
Materials Science, Multidisciplinary
Lingjun Xu, Pruch Kijkla, Sith Kumseranee, Suchada Punpruk, Tingyue Gu
JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
(2024)
Article
Materials Science, Multidisciplinary
X. P. Hu, Y. H. Zhang, C. B. Liu, H. Z. Cui
Summary: In this study, a novel polyaniline (PANI) nanosheet with barrier and passivation functions was synthesized, and its interaction with polymeric resin was enhanced by polydopamine (PDA) wrapping. The composite coating with incorporated PANI@PDA nanosheets showed improved corrosion resistance by providing a longer penetration path and inducing the formation of a passivation film on the metal substrate.
JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
(2024)
Article
Materials Science, Multidisciplinary
Yan Zhang, Xuehua Liu, Zhiqiang Guo, Chenyu Jia, Feng Lu, Zirui Jia, Guanglei Wu
Summary: In this study, a self-assembling-etching-anchoring growth method was proposed to prepare MXene@Co electromagnetic wave absorbing materials. The hollow structure design and surface anchored growth of magnetic Co particles significantly enhanced the wave absorption performance of the absorber.
JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
(2024)
Review
Materials Science, Multidisciplinary
Yajing Ren, Yunfeng Li, Guixu Pan, Ning Wang, Yan Xing, Zhenyi Zhang
Summary: Photocatalytic technology utilizing sunlight as a driving force can convert solar energy into other energy sources for storage and use. CdS, as a typical reducing semiconductor, has attracted attention in photocatalysis due to its suitable bandgap and strong reducing ability. However, the photocatalytic performance of CdS is limited by carrier recombination and photocorrosion. Therefore, CdS has been widely developed as a reducing photocatalyst in constructing S-scheme heterojunctions to overcome these limitations.
JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
(2024)
Article
Materials Science, Multidisciplinary
Diao-Feng Li, Chun-Guang Bai, Zhi-Qiang Zhang, Hui-Bo Zhang, Nan Li, Jian Zhao
Summary: A novel compliant spinal fixation based on compliant mechanisms is designed to effectively reduce stress-shielding effect and adjacent segment degeneration (ASD), but it requires high properties of the used materials. Bulk metallic glasses (BMGs), as young biomaterials, demonstrate excellent comprehensive properties, making them attractive for compliant spinal fixation. In this study, the large deflection deformation behaviors of Zr61Ti2Cu25Al12 (at.%, ZT1) BMG beam were systematically investigated, including elastic, yielding, and plastic deformations. The theoretical nonlinear analytical solution curve predicts the load-deflection relation within the elastic deformation regime and assists in capturing the yielding event, serving as a powerful design tool for engineers. To accurately capture the beginning of the yielding event in biomedical implant applications, the concept of bending proof strength (sigma p,0.05%) with tiny permanent strain of 0.05% was proposed and determined, which is significant for setting the allowable operating limits of the basic flexible elements. The plastic deformation driven by the bending moment can be classified into two stages: the initial stage characterized by nucleation and intense interaction of shear bands, and the second stage dominated by the progressive propagation of shear bands and emergence of shear offsets. The plasticity of BMG beam structures depends on the BMG's inherent plastic zone size (rp), and when the half beam thickness is less than that of rp, the plastic deformation of BMGs behaves in a stable manner, effectively serving as the margin of safety.
JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
(2024)
Review
Materials Science, Multidisciplinary
Yanlin Li, Zhu Ma, Shanyue Hou, Qianyu Liu, Guangyuan Yan, Xiaoshan Li, Tangjie Yu, Zhuowei Du, Junbo Yang, Yi Chen, Wei You, Qiang Yang, Yan Xiang, Shufang Tang, Xuelin Yue, Meng Zhang, Wenfeng Zhang, Jian Yu, Yuelong Huang, Jiale Xie, Chun Tang, Yaohua Mai, Kuan Sun
Summary: This paper provides an overview of hydrogen progress from solar energy to solar cells, with a focus on photovoltaic-electrolysis and photoelectrochemical/photovoltaic systems. Both systems have achieved a solar-to-hydrogen efficiency of over 10% and show great potential for large-scale application. The challenges and opportunities in this field, including configuration design, electrode materials, and performance evaluation, are summarized. The paper also analyzes and presents perspectives on the potential commercial application and further scientific research for the development of solar-to-hydrogen.
JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
(2024)
Article
Materials Science, Multidisciplinary
L. K. Huang, F. Liu, M. X. Huang
Summary: The bainite transformation in medium Mn steels has been experimentally and theoretically studied, and it has been found that the transformation kinetics is slow. However, the introduction of dislocations can significantly accelerate the transformation rate. A new "carbon depletion mechanism" is proposed to explain the role of dislocations in the acceleration of bainite transformation, and a physical model is developed to quantitatively understand the kinetics of bainite transformation.
JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
(2024)
Review
Materials Science, Multidisciplinary
Jing Qiao, Lutong Li, Jiurong Liu, Na Wu, Wei Liu, Fan Wu, Zhihui Zeng
Summary: Rare earth plays a crucial role in electromagnetic wave absorption materials, and the strategies of doping rare earth elements and constructing rare earth oxide composites are important for the fabrication of high-efficiency electromagnetic wave absorption materials. This review provides a comprehensive summary of the research background, classification, features, progress, and future development of rare earth electromagnetic wave absorption materials, offering guidance for future development.
JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
(2024)
Article
Materials Science, Multidisciplinary
Jiacheng Ge, Yao Gu, Zhongzheng Yao, Sinan Liu, Huiqiang Ying, Chenyu Lu, Zhenduo Wu, Yang Ren, Jun-ichi Suzuki, Zhenhua Xie, Yubin Ke, Jianrong Zeng, He Zhu, Song Tang, Xun-Li Wang, Si Lan
Summary: Fe-based metallic glasses are promising materials in the fields of advanced magnetism and sensors. This study proposes a novel approach to tailor the amorphous structure through liquid-liquid phase transition, and provides insights into the correlation between structural disorder and magnetic order. The results show that the liquid-liquid phase transition can induce more locally ordered nanodomains, leading to stronger exchange interactions and increased saturation magnetization. The increased local heterogeneity also enhances magnetic anisotropy, resulting in a better stress-impedance effect.
JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
(2024)
Article
Materials Science, Multidisciplinary
Hao Yu, Xin Kou, Xueqing Zuo, Ding Xi, Haijun Guan, Pengfei Yin, Lijia Xu, Yongpeng Zhao
Summary: Metal-organic frameworks derived composites are promising EMW absorbers. Cation substitution can improve their absorption performance by regulating morphology and atomic space occupation. However, the mechanisms of how cation substitution affects EMW absorption performance are still not well understood. In this study, imidazolic MOFs were fabricated and tailored by cation substitution strategy to prepare porous composites. The samples showed optimal reflection loss and effective absorption bandwidth values under low filling rate and thin thickness conditions. The intercoupling between multiple atoms and the porous structure introduced by cation substitution contribute to the improved absorption performance.
JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
(2024)
Article
Materials Science, Multidisciplinary
Lina Wang, Peiyi Yan, Huairui Chen, Zhuo Li, Shu Jin, Xiaoxiang Xu, Jun Qian
Summary: The narrow bandgap semiconductor MgIn2S4 has been grown onto In2O3 nanofibers using an in situ growing method. The resulting MgIn2S4-In2O3 hybrid nanofibers exhibit strong visible light absorption and intimate MgIn2S4/In2O3 heterointerfaces, leading to highly efficient photocatalytic disinfection of Escherichia coli.
JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
(2024)