SMC complexes can traverse physical roadblocks bigger than their ring size

DNA tension-modulated translocation and loop extrusion by SMC complexes revealed by molecular dynamics simulations

(2022) Stefanos K Nomidis et al.   NUCLEIC ACIDS RESEARCH

A hold-and-feed mechanism drives directional DNA loop extrusion by condensin

(2022) Indra A. Shaltiel et al.   SCIENCE

ParB proteins can bypass DNA-bound roadblocks via dimer-dimer recruitment

(2022) Miloš Tišma et al.   Science Advances

Cohesin architecture and clustering in vivo

(2021) Siheng Xiang et al.   eLife

Bridging-induced phase separation induced by cohesin SMC protein complexes

(2021) Je-Kyung Ryu et al.   Science Advances

DNA-loop extruding condensin complexes can traverse one another

(2020) Eugene Kim et al.   NATURE

The structural basis for cohesin–CTCF-anchored loops

(2020) Yan Li et al.   NATURE

SciPy 1.0: fundamental algorithms for scientific computing in Python

(2020) Pauli Virtanen et al.   NATURE METHODS

Human Condensin I and II Drive Extensive ATP-Dependent Compaction of Nucleosome-Bound DNA

(2020) Muwen Kong et al.   MOLECULAR CELL

Cohesin and condensin extrude DNA loops in a cell-cycle dependent manner

(2020) Stefan Golfier et al.   eLife

A Structure-Based Mechanism for DNA Entry into the Cohesin Ring

(2020) Torahiko L. Higashi et al.   MOLECULAR CELL

Cryo-EM structures of holo condensin reveal a subunit flip-flop mechanism

(2020) Byung-Gil Lee et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The condensin holocomplex cycles dynamically between open and collapsed states

(2020) Je-Kyung Ryu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

DNA-segment-capture model for loop extrusion by structural maintenance of chromosome (SMC) protein complexes

(2019) John F Marko et al.   NUCLEIC ACIDS RESEARCH

RNA polymerases as moving barriers to condensin loop extrusion

(2019) Hugo B. Brandão et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Cohesin Ring Uses Its Hinge to Organize DNA Using Non-topological as well as Topological Mechanisms

(2018) Madhusudhan Srinivasan et al.   CELL

Real-time imaging of DNA loop extrusion by condensin

(2018) Mahipal Ganji et al.   SCIENCE

SMC Complexes: Universal DNA Looping Machines with Distinct Regulators

(2018) Marjon S. van Ruiten et al.   TRENDS IN GENETICS

Transcription Elongation Can Affect Genome 3D Structure

(2018) Sven Heinz et al.   CELL

A tethered-inchworm model of SMC DNA translocation

(2018) Michael H. Nichols et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Towards a Unified Model of SMC Complex Function

(2018) Markus Hassler et al.   CURRENT BIOLOGY

Structure of Full-Length SMC and Rearrangements Required for Chromosome Organization

(2017) Marie-Laure Diebold-Durand et al.   MOLECULAR CELL

Cohesin is positioned in mammalian genomes by transcription, CTCF and Wapl

(2017) Georg A. Busslinger et al.   NATURE

Condensin-Based Chromosome Organization from Bacteria to Vertebrates

(2016) Tatsuya Hirano   CELL

Rapid movement and transcriptional re‐localization of human cohesin on DNA

(2016) Iain F Davidson et al.   EMBO JOURNAL

SMC complexes: from DNA to chromosomes

(2016) Frank Uhlmann   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Single-Molecule Imaging Reveals a Collapsed Conformational State for DNA-Bound Cohesin

(2016) Johannes Stigler et al.   Cell Reports

Compaction and segregation of sister chromatids via active loop extrusion

(2016) Anton Goloborodko et al.   eLife

The architecture of a eukaryotic replisome

(2015) Jingchuan Sun et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The architecture of a eukaryotic replisome

(2015) Jingchuan Sun et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

SMC condensin entraps chromosomal DNA by an ATP hydrolysis dependent loading mechanism in Bacillus subtilis

(2015) Larissa Wilhelm et al.   eLife

Cys-Pair Reporters Detect a Constrained Trigger Loop in a Paused RNA Polymerase

(2013) Dhananjaya Nayak et al.   MOLECULAR CELL

Organization of the Mitotic Chromosome

(2013) N. Naumova et al.   SCIENCE

Condensin structures chromosomal DNA through topological links

(2011) Sara Cuylen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Biophysical Characterization of the Centromere-specific Nucleosome from Budding Yeast

(2010) Isabel J. Kingston et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The cohesin ring concatenates sister DNA molecules

(2008) Christian H. Haering et al.   NATURE

Highly inclined thin illumination enables clear single-molecule imaging in cells

(2008) Makio Tokunaga et al.   NATURE METHODS