A calculated risk: Evaluating HIV resistance to the broadly neutralising antibodies10-1074 and 3BNC117

Combination anti-HIV antibodies provide sustained virological suppression

(2022) Michael C. Sneller et al.   NATURE

Prolonged viral suppression with anti-HIV-1 antibody therapy

(2022) Christian Gaebler et al.   NATURE

Super LeArner Prediction of NAb Panels (SLAPNAP): a containerized tool for predicting combination monoclonal broadly neutralizing antibody sensitivity

(2021) Brian D Williamson et al.   BIOINFORMATICS

Predicting in vivo escape dynamics of HIV-1 from a broadly neutralizing antibody

(2021) Matthijs Meijers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Structural Update of Neutralizing Epitopes on the HIV Envelope, a Moving Target

(2021) Emma Parker Miller et al.   Viruses-Basel

Broadly Neutralizing Antibodies for HIV-1 Prevention

(2021) Stephen R. Walsh et al.   Frontiers in Immunology

Characterizing the Relationship Between Neutralization Sensitivity and env Gene Diversity During ART Suppression

(2021) Andrew Wilson et al.   Frontiers in Immunology

Can Broadly Neutralizing HIV-1 Antibodies Help Achieve an ART-Free Remission?

(2021) Denise C. Hsu et al.   Frontiers in Immunology

Clinical Trials of Broadly Neutralizing Monoclonal Antibodies for Human Immunodeficiency Virus Prevention: A Review

(2020) Sharana Mahomed et al.   JOURNAL OF INFECTIOUS DISEASES

Sequence evaluation and comparative analysis of novel assays for intact proviral HIV-1 DNA

(2020) Christian Gaebler et al.   JOURNAL OF VIROLOGY

HIV-1 Neutralizing Antibody Signatures and Application to Epitope-Targeted Vaccine Design

(2019) Christine A. Bricault et al.   Cell Host & Microbe

An Antigenic Atlas of HIV-1 Escape from Broadly Neutralizing Antibodies Distinguishes Functional and Structural Epitopes

(2019) Adam S. Dingens et al.   IMMUNITY

Broadly neutralizing anti-HIV-1 monoclonal antibodies in the clinic

(2019) Marina Caskey et al.   NATURE MEDICINE

Impact of HIV-1 Diversity on Its Sensitivity to Neutralization

(2019) Karl Stefic et al.   Vaccines

Accurate Prediction for Antibody Resistance of Clinical HIV-1 Isolates

(2019) Reda Rawi et al.   Scientific Reports

Broadly neutralizing antibodies for the treatment and prevention of HIV infection

(2019) Marina Caskey   Current Opinion in HIV and AIDS

Structural characterization of a highly-potent V3-glycan broadly neutralizing antibody bound to natively-glycosylated HIV-1 envelope

(2018) Christopher O. Barnes et al.   Nature Communications

Relationship between latent and rebound viruses in a clinical trial of anti–HIV-1 antibody 3BNC117

(2018) Yehuda Z. Cohen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Combination therapy with anti-HIV-1 antibodies maintains viral suppression

(2018) Pilar Mendoza et al.   NATURE

Safety and antiviral activity of combination HIV-1 broadly neutralizing antibodies in viremic individuals

(2018) Yotam Bar-On et al.   NATURE MEDICINE

Recent progress in broadly neutralizing antibodies to HIV

(2018) Devin Sok et al.   NATURE IMMUNOLOGY

Antibody 10-1074 suppresses viremia in HIV-1-infected individuals

(2017) Marina Caskey et al.   NATURE MEDICINE

Prediction of HIV-1 sensitivity to broadly neutralizing antibodies shows a trend towards resistance over time

(2017) Anna Hake et al.   PLoS Computational Biology

Probability of N332 glycan occupancy on HIV-1 gp120 modulates sensitivity to broadly neutralizing antibodies

(2016) Tom L.G.M. van den Kerkhof et al.   AIDS

Broadly Neutralizing Antibodies to HIV and Their Role in Vaccine Design

(2016) Dennis R. Burton et al.   Annual Review of Immunology

A Prominent Site of Antibody Vulnerability on HIV Envelope Incorporates a Motif Associated with CCR5 Binding and Its Camouflaging Glycans

(2016) Devin Sok et al.   IMMUNITY

HIV-1 antibody 3BNC117 suppresses viral rebound in humans during treatment interruption

(2016) Johannes F. Scheid et al.   NATURE

Determinants of HIV-1 broadly neutralizing antibody induction

(2016) Peter Rusert et al.   NATURE MEDICINE

Effect of HIV Antibody VRC01 on Viral Rebound after Treatment Interruption

(2016) Katharine J. Bar et al.   NEW ENGLAND JOURNAL OF MEDICINE

HIV-1 therapy with monoclonal antibody 3BNC117 elicits host immune responses against HIV-1

(2016) T. Schoofs et al.   SCIENCE

Strain-Specific V3 and CD4 Binding Site Autologous HIV-1 Neutralizing Antibodies Select Neutralization-Resistant Viruses

(2015) M. Anthony Moody et al.   Cell Host & Microbe

HIV-1 Fitness Cost Associated with Escape from the VRC01 Class of CD4 Binding Site Neutralizing Antibodies

(2015) Rebecca M. Lynch et al.   JOURNAL OF VIROLOGY

Viraemia suppressed in HIV-1-infected humans by broadly neutralizing antibody 3BNC117

(2015) Marina Caskey et al.   NATURE

Development of broadly neutralizing antibodies from autologous neutralizing antibody responses in HIV infection

(2014) Cynthia A. Derdeyn et al.   Current Opinion in HIV and AIDS

IDEPI: Rapid Prediction of HIV-1 Antibody Epitopes and Other Phenotypic Features from Sequence Data Using a Flexible Machine Learning Platform

(2014) N. Lance Hepler et al.   PLoS Computational Biology

HIV-1 neutralizing antibodies: understanding nature's pathways

(2013) John R. Mascola et al.   IMMUNOLOGICAL REVIEWS

Computational analysis of anti-HIV-1 antibody neutralization panel data to identify potential functional epitope residues

(2013) A. P. West et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Viral Escape from HIV-1 Neutralizing Antibodies Drives Increased Plasma Neutralization Breadth through Sequential Recognition of Multiple Epitopes and Immunotypes

(2013) Constantinos Kurt Wibmer et al.   PLoS Pathogens

Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies

(2012) H. Mouquet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Longer V1V2 Region with Increased Number of Potential N-Linked Glycosylation Sites in the HIV-1 Envelope Glycoprotein Protects against HIV-Specific Neutralizing Antibodies

(2011) M. J. van Gils et al.   JOURNAL OF VIROLOGY

Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding

(2011) J. F. Scheid et al.   SCIENCE

A flexible and efficient template format for circular consensus sequencing and SNP detection

(2010) K. J. Travers et al.   NUCLEIC ACIDS RESEARCH

HIV-1 Envelope Subregion Length Variation during Disease Progression

(2010) Marcel E. Curlin et al.   PLoS Pathogens

Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals

(2009) Johannes F. Scheid et al.   NATURE

Deciphering Human Immunodeficiency Virus Type 1 Transmission and Early Envelope Diversification by Single-Genome Amplification and Sequencing

(2008) J. F. Salazar-Gonzalez et al.   JOURNAL OF VIROLOGY