The alternative splicing of intersectin 1 regulated by PTBP1 promotes human glioma progression

An in vitro reconstituted U1 snRNP allows the study of the disordered regions of the particle and the interactions with proteins and ligands

(2021) Sébastien Campagne et al.   NUCLEIC ACIDS RESEARCH

Alternative splicing-derived intersectin1-L and intersectin1-S exert opposite function in glioma progression

(2019) Ying Shao et al.   Cell Death & Disease

Glioma infiltration and extracellular matrix: key players and modulators

(2018) Valéria Pereira Ferrer et al.   GLIA

Alternative-splicing defects in cancer: Splicing regulators and their downstream targets, guiding the way to novel cancer therapeutics

(2018) Laura M. Urbanski et al.   Wiley Interdisciplinary Reviews-RNA

Splicing factor SRSF1 promotes gliomagenesis via oncogenic splice-switching of MYO1B

(2018) Xuexia Zhou et al.   JOURNAL OF CLINICAL INVESTIGATION

Epithelial-mesenchymal transition in glioblastoma progression

(2016) YASUO IWADATE   Oncology Letters

Intersectin1-s, A multidomain adapter protein, Is essential for malignant glioma proliferation

(2015) Feng Gu et al.   GLIA

Alternative Splicing in the Mammalian Nervous System: Recent Insights into Mechanisms and Functional Roles

(2015) Bushra Raj et al.   NEURON

Glioma

(2015) Michael Weller et al.   Nature Reviews Disease Primers

Lineage-specific splicing of a brain-enriched alternative exon promotes glioblastoma progression

(2014) Roberto Ferrarese et al.   JOURNAL OF CLINICAL INVESTIGATION

A neurocentric perspective on glioma invasion

(2014) Vishnu Anand Cuddapah et al.   NATURE REVIEWS NEUROSCIENCE

Alternative splicing in cancer: implications for biology and therapy

(2014) J Chen et al.   ONCOGENE

Alternative splicing: a pivotal step between eukaryotic transcription and translation

(2013) Alberto R. Kornblihtt et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Intersectin: The Crossroad between Vesicle Exocytosis and Endocytosis

(2013) Olga Gubar et al.   Frontiers in Endocrinology

RNA therapeutics: beyond RNA interference and antisense oligonucleotides

(2012) Ryszard Kole et al.   NATURE REVIEWS DRUG DISCOVERY

Intersectin1-s is involved in migration and invasion of human glioma cells

(2011) Yongjie Ma et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Exon skipping and dystrophin restoration in patients with Duchenne muscular dystrophy after systemic phosphorodiamidate morpholino oligomer treatment: an open-label, phase 2, dose-escalation study

(2011) Sebahattin Cirak et al.   LANCET

U1 snRNA Directly Interacts with Polypyrimidine Tract-Binding Protein during Splicing Repression

(2011) Shalini Sharma et al.   MOLECULAR CELL

Systemic Administration of PRO051 in Duchenne's Muscular Dystrophy

(2011) Nathalie M. Goemans et al.   NEW ENGLAND JOURNAL OF MEDICINE

Exon-centric regulation of pyruvate kinase M alternative splicing via mutually exclusive exons

(2011) Zhenxun Wang et al.   Journal of Molecular Cell Biology

The G-protein-coupled formylpeptide receptor FPR confers a more invasive phenotype on human glioblastoma cells

(2010) J Huang et al.   BRITISH JOURNAL OF CANCER

Expansion of the eukaryotic proteome by alternative splicing

(2010) Timothy W. Nilsen et al.   NATURE

Position-dependent alternative splicing activity revealed by global profiling of alternative splicing events regulated by PTB

(2010) Miriam Llorian et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Low-Density Lipoprotein Receptor-Related Protein 1 Promotes Cancer Cell Migration and Invasion by Inducing the Expression of Matrix Metalloproteinases 2 and 9

(2009) H. Song et al.   CANCER RESEARCH

Reduction of protein kinase C ζ inhibits migration and invasion of human glioblastoma cells

(2009) Hua Guo et al.   JOURNAL OF NEUROCHEMISTRY

HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer

(2009) Charles J. David et al.   NATURE

SnapShot: The Splicing Regulatory Machinery

(2008) Mathieu Gabut et al.   CELL

Alternative isoform regulation in human tissue transcriptomes

(2008) Eric T. Wang et al.   NATURE