A randomized, double-blind, placebo-controlled, hybrid parallel-arm study of low-dose naltrexone as an adjunctive anti-inflammatory treatment for major depressive disorder

Human EEG and the mechanisms of memory: investigating long-term potentiation (LTP) in sensory-evoked potentials

(2020) Ian J. Kirk et al.   JOURNAL OF THE ROYAL SOCIETY OF NEW ZEALAND

Evidence of widespread metabolite abnormalities in Myalgic encephalomyelitis/chronic fatigue syndrome: assessment with whole-brain magnetic resonance spectroscopy

(2019) Christina Mueller et al.   Brain Imaging and Behavior

Markers of central inflammation in major depressive disorder: A systematic review and meta-analysis of studies examining cerebrospinal fluid, positron emission tomography and post-mortem brain tissue

(2019) Daniela Enache et al.   BRAIN BEHAVIOR AND IMMUNITY

Selective effects of acute low-grade inflammation on human visual attention

(2019) Leonie JT. Balter et al.   NEUROIMAGE

Inflamed depression

(2018) Edward Bullmore   LANCET

Inflammatory profiles of severe treatment-resistant depression

(2018) Rebecca Strawbridge et al.   JOURNAL OF AFFECTIVE DISORDERS

Randomized, proof-of-concept trial of low dose naltrexone for patients with breakthrough symptoms of major depressive disorder on antidepressants

(2017) David Mischoulon et al.   JOURNAL OF AFFECTIVE DISORDERS

Assessing Lifetime Stress Exposure using the Stress and Adversity Inventory for Adults (Adult STRAIN)

(2017) George M. Slavich et al.   PSYCHOSOMATIC MEDICINE

Quantification of normal-appearing white matter tract integrity in multiple sclerosis: a diffusion kurtosis imaging study

(2016) Ivan de Kouchkovsky et al.   JOURNAL OF NEUROLOGY

Role of neuroinflammation in neurodegenerative diseases (Review)

(2016) WEI-WEI CHEN et al.   Molecular Medicine Reports

Quantitative Magnetization Transfer Imaging as a Biomarker for Effects of Systemic Inflammation on the Brain

(2015) Neil A. Harrison et al.   BIOLOGICAL PSYCHIATRY

Opioid growth factor and low-dose naltrexone impair central nervous system infiltration by CD4 + T lymphocytes in established experimental autoimmune encephalomyelitis, a model of multiple sclerosis

(2015) Leslie A Hammer et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

A critical review of the efficacy of non-steroidal anti-inflammatory drugs in depression

(2015) Harris A. Eyre et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Inflammation and depression: combined use of selective serotonin reuptake inhibitors and NSAIDs or paracetamol and psychiatric outcomes

(2015) Ole Köhler et al.   Brain and Behavior

A longitudinal evaluation of diffusion kurtosis imaging in patients with mild traumatic brain injury

(2014) Jesse A. Stokum et al.   BRAIN INJURY

The use of low-dose naltrexone (LDN) as a novel anti-inflammatory treatment for chronic pain

(2014) Jarred Younger et al.   CLINICAL RHEUMATOLOGY

Can diffusion kurtosis imaging improve the sensitivity and specificity of detecting microstructural alterations in brain tissue chronically after experimental stroke? Comparisons with diffusion tensor imaging and histology

(2014) S. Umesh Rudrapatna et al.   NEUROIMAGE

The reward positivity: From basic research on reward to a biomarker for depression

(2014) Greg Hajcak Proudfit   PSYCHOPHYSIOLOGY

Effect of Anti-inflammatory Treatment on Depression, Depressive Symptoms, and Adverse Effects

(2014) Ole Köhler et al.   JAMA Psychiatry

Low-dose naltrexone for the treatment of fibromyalgia: Findings of a small, randomized, double-blind, placebo-controlled, counterbalanced, crossover trial assessing daily pain levels

(2013) Jarred Younger et al.   ARTHRITIS AND RHEUMATISM

Cognition assessment using the NIH Toolbox

(2013) S. Weintraub et al.   NEUROLOGY

Development of the Stanford Expectations of Treatment Scale (SETS): A tool for measuring patient outcome expectancy in clinical trials

(2012) Jarred Younger et al.   Clinical Trials

Therapy with the Opioid Antagonist Naltrexone Promotes Mucosal Healing in Active Crohn’s Disease: A Randomized Placebo-Controlled Trial

(2011) Jill P. Smith et al.   DIGESTIVE DISEASES AND SCIENCES

Low-dose naltrexone targets the opioid growth factor–opioid growth factor receptor pathway to inhibit cell proliferation: mechanistic evidence from a tissue culture model

(2011) Renee N Donahue et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Diffusion kurtosis as an in vivo imaging marker for reactive astrogliosis in traumatic brain injury

(2011) Jiachen Zhuo et al.   NEUROIMAGE

The effect of low-dose naltrexone on quality of life of patients with multiple sclerosis: a randomized placebo-controlled trial

(2010) Naser Sharafaddinzadeh et al.   Multiple Sclerosis Journal

Assessing general side effects in clinical trials: reference data from the general population

(2010) Winfried Rief et al.   PHARMACOEPIDEMIOLOGY AND DRUG SAFETY

Neural Origins of Human Sickness in Interoceptive Responses to Inflammation

(2009) Neil A. Harrison et al.   BIOLOGICAL PSYCHIATRY

Development and reliability of a structured interview guide for the Montgomery-Åsberg Depression Rating Scale (SIGMA)

(2008) Janet B. W. Williams et al.   BRITISH JOURNAL OF PSYCHIATRY

Non-stereoselective reversal of neuropathic pain by naloxone and naltrexone: involvement of toll-like receptor 4 (TLR4)

(2008) Mark R. Hutchinson et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Research electronic data capture (REDCap)—A metadata-driven methodology and workflow process for providing translational research informatics support

(2008) Paul A. Harris et al.   JOURNAL OF BIOMEDICAL INFORMATICS

From inflammation to sickness and depression: when the immune system subjugates the brain

(2007) Robert Dantzer et al.   NATURE REVIEWS NEUROSCIENCE