Carbon-negative synthetic biology: challenges and emerging trends of cyanobacterial technology

Carbon-negative production of acetone and isopropanol by gas fermentation at industrial pilot scale

(2022) Fungmin Eric Liew et al.   NATURE BIOTECHNOLOGY

Machine learning-informed and synthetic biology-enabled semi-continuous algal cultivation to unleash renewable fuel productivity

(2022) Bin Long et al.   Nature Communications

3D-printed hierarchical pillar array electrodes for high-performance semi-artificial photosynthesis

(2022) Xiaolong Chen et al.   NATURE MATERIALS

Two major metabolic factors for an efficient NADP-malic enzyme type C4 photosynthesis

(2022) Honglong Zhao et al.   PLANT PHYSIOLOGY

Synthetic metabolic pathways for conversion of CO2 into secreted short-to medium-chain hydrocarbons using cyanobacteria

(2022) Ian S. Yunus et al.   METABOLIC ENGINEERING

Mucin induces CRISPR-Cas defense in an opportunistic pathogen

(2022) Gabriel Magno de Freitas Almeida et al.   Nature Communications

Biocontainment of Engineered Synechococcus elongatus PCC 7942 for Photosynthetic Production of α-Farnesene from CO2

(2021) Hyun Jeong Lee et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Photoautotrophic production of p-Coumaric acid using genetically engineered Synechocystis sp. Pasteur Culture Collection 6803

(2021) E-Bin Gao et al.   Algal Research-Biomass Biofuels and Bioproducts

Salt-Tolerant Synechococcus elongatus UTEX 2973 Obtained via Engineering of Heterologous Synthesis of Compatible Solute Glucosylglycerol

(2021) Jinyu Cui et al.   Frontiers in Microbiology

Enhancing carbohydrate repartitioning into lipid and carotenoid by disruption of microalgae starch debranching enzyme

(2021) Yuichi Kato et al.   Communications Biology

Wearable materials with embedded synthetic biology sensors for biomolecule detection

(2021) Peter Q. Nguyen et al.   NATURE BIOTECHNOLOGY

Transgenic mice for in vivo epigenome editing with CRISPR-based systems

(2021) Matthew P. Gemberling et al.   NATURE METHODS

Cell-free chemoenzymatic starch synthesis from carbon dioxide

(2021) Tao Cai et al.   SCIENCE

Structural insight into the mechanism of energy transfer in cyanobacterial phycobilisomes

(2021) Lvqin Zheng et al.   Nature Communications

A natural riboswitch scaffold with self-methylation activity

(2021) Laurin Flemmich et al.   Nature Communications

Establishment of a Biosensor-based High-Throughput Screening Platform for Tryptophan Overproduction

(2021) Yongfei Liu et al.   ACS Synthetic Biology

Development of a N-Acetylneuraminic Acid-Based Sensing and Responding Switch for Orthogonal Gene Regulation in Cyanobacterial Synechococcus Strains

(2021) Xuyang Sun et al.   ACS Synthetic Biology

Metabolic network remodelling enhances yeast’s fitness on xylose using aerobic glycolysis

(2021) Xiaowei Li et al.   Nature Catalysis

Engineering Natural Competence into the Fast-Growing Cyanobacterium Synechococcus elongatus Strain UTEX 2973

(2021) Kristen E. Wendt et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Cycling between growth and production phases increases cyanobacteria bioproduction of lactate

(2021) Kiyan Shabestary et al.   METABOLIC ENGINEERING

A systematic genome-wide mapping of oncogenic mutation selection during CRISPR-Cas9 genome editing

(2021) Sanju Sinha et al.   Nature Communications

Coalescence and directed anisotropic growth of starch granule initials in subdomains of Arabidopsis thaliana chloroplasts

(2021) Léo Bürgy et al.   Nature Communications

Computational Framework for Machine-Learning-Enabled 13C Fluxomics

(2021) Chao Wu et al.   ACS Synthetic Biology

Systematic Engineering of Synechococcus elongatus UTEX 2973 for Photosynthetic Production of l-Lysine, Cadaverine, and Glutarate

(2021) Zachary A. Dookeran et al.   ACS Synthetic Biology

Increased ethylene production by overexpressing phosphoenolpyruvate carboxylase in the cyanobacterium Synechocystis PCC 6803

(2020) Claudia Durall et al.   Biotechnology for Biofuels

High-throughput identification of synthetic riboswitches by barcode-free amplicon-sequencing in human cells

(2020) Benjamin Strobel et al.   Nature Communications

Enhanced production of sucrose in the fast-growing cyanobacterium Synechococcus elongatus UTEX 2973

(2020) Po-Cheng Lin et al.   Scientific Reports

Tailoring bacterial cellulose structure through CRISPR interference‐mediated downregulation of galU in Komagataeibacter xylinus CGMCC 2955

(2020) Long‐Hui Huang et al.   BIOTECHNOLOGY AND BIOENGINEERING

Synechococcus elongatus PCC7942: a cyanobacterium cell factory for producing useful chemicals and fuels under abiotic stress conditions

(2020) Dimitrios Vayenos et al.   PHOTOSYNTHESIS RESEARCH

Pooled CRISPRi screening of the cyanobacterium Synechocystis sp PCC 6803 for enhanced industrial phenotypes

(2020) Lun Yao et al.   Nature Communications

Dissolved oxygen from microalgae-gel patch promotes chronic wound healing in diabetes

(2020) Huanhuan Chen et al.   Science Advances

Cyanobacteria-Based Bio-Oxygen Pump Promoting Hypoxia-Resistant Photodynamic Therapy

(2020) Tao Sun et al.   Frontiers in Bioengineering and Biotechnology

Third-generation biorefineries as the means to produce fuels and chemicals from CO2

(2020) Zihe Liu et al.   Nature Catalysis

Synthetic microbial communities of heterotrophs and phototrophs facilitate sustainable growth

(2020) Cristal Zuñiga et al.   Nature Communications

Newly discovered Synechococcus sp. PCC 11901 is a robust cyanobacterial strain for high biomass production

(2020) Artur Włodarczyk et al.   Communications Biology

Tailoring cyanobacteria as a new platform for highly efficient synthesis of astaxanthin

(2020) Jinjin Diao et al.   METABOLIC ENGINEERING

Maximizing PHB content in Synechocystis sp. PCC 6803: a new metabolic engineering strategy based on the regulator PirC

(2020) Moritz Koch et al.   Microbial Cell Factories

A natural in situ fabrication method of functional bacterial cellulose using a microorganism

(2019) Minghong Gao et al.   Nature Communications

A Cytosolic Bypass and G6P Shunt in Plants Lacking Peroxisomal Hydroxypyruvate Reductase

(2019) Jiying Li et al.   PLANT PHYSIOLOGY

Identification of two two-component signal transduction mutants with enhanced sucrose biosynthesis in Synechococcus elongatus PCC 7942

(2019) Cuncun Qiao et al.   JOURNAL OF BASIC MICROBIOLOGY

Photosynthetic generation of heterologous terpenoids in cyanobacteria

(2019) Nico Betterle et al.   BIOTECHNOLOGY AND BIOENGINEERING

Collaborative networks in gene editing

(2019) Ying Huang et al.   NATURE BIOTECHNOLOGY

Glycogen metabolism supports photosynthesis start through the OPP pathway in cyanobacteria

(2019) Shrameeta Shinde et al.   PLANT PHYSIOLOGY

Programmable biomolecular switches for rewiring flux in Escherichia coli

(2019) Cong Gao et al.   Nature Communications

Improving hydrocarbon production by engineering cyanobacterial acyl-(acyl carrier protein) reductase

(2019) Hisashi Kudo et al.   Biotechnology for Biofuels

Metabolic engineering of Synechocystis sp. PCC 6803 for the production of aromatic amino acids and derived phenylpropanoids

(2019) Laura Furelos Brey et al.   METABOLIC ENGINEERING

Competition between Granule Bound Starch Synthase and Starch Branching Enzyme in Starch Biosynthesis

(2019) Huaxin Han et al.   Rice

Tunable Repression of Key Photosynthetic Processes Using Cas12a CRISPR Interference in the Fast-Growing Cyanobacterium Synechococcus sp. UTEX 2973

(2019) Cory J. Knoot et al.   ACS Synthetic Biology

Photosynthetic conversion of CO2 to hyaluronic acid by engineered strains of the cyanobacterium Synechococcus sp. PCC 7002

(2019) Lifang Zhang et al.   Algal Research-Biomass Biofuels and Bioproducts

Toolboxes for cyanobacteria: Recent advances and future direction

(2018) Tao Sun et al.   BIOTECHNOLOGY ADVANCES

Re-direction of carbon flux to key precursor malonyl-CoA via artificial small RNAs in photosynthetic Synechocystis sp. PCC 6803

(2018) Tao Sun et al.   Biotechnology for Biofuels

Glycogen Production in Marine Cyanobacterial Strain Synechococcus sp. NKBG 15041c

(2018) Amr Badary et al.   MARINE BIOTECHNOLOGY

Development and optimization of genetic toolboxes for a fast-growing cyanobacterium Synechococcus elongatus UTEX 2973

(2018) Shubin Li et al.   METABOLIC ENGINEERING

Improving the induction fold of riboregulators for cyanobacteria

(2018) Ippei Sakamoto et al.   RNA Biology

CRISPR-Based Technologies for Metabolic Engineering in Cyanobacteria

(2018) Juliane Behler et al.   TRENDS IN BIOTECHNOLOGY

Riboswitch regulation in cyanobacteria is independent of their habitat adaptations

(2018) Payal Singh et al.   PHYSIOLOGY AND MOLECULAR BIOLOGY OF PLANTS

Requirement of alkanes for salt tolerance of Cyanobacteria: characterization of alkane synthesis genes from salt-sensitive Synechococcus elongatus PCC7942 and salt-tolerant Aphanothece halophytica

(2018) T. Yamamori et al.   LETTERS IN APPLIED MICROBIOLOGY

Remodeling of the Photosynthetic Chain Promotes Direct CO2 Conversion into Valuable Aromatic Compounds

(2018) Jun Ni et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Starch granule initiation and morphogenesis—progress in Arabidopsis and cereals

(2018) David Seung et al.   JOURNAL OF EXPERIMENTAL BOTANY

A Coenzyme-Free Biocatalyst for the Value-Added Utilization of Lignin-Derived Aromatics

(2018) Jun Ni et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Bacterial Nanobionics via 3D Printing

(2018) Sudeep Joshi et al.   NANO LETTERS

Expanding the Potential of CRISPR-Cpf1-Based Genome Editing Technology in the Cyanobacterium Anabaena PCC 7120

(2018) Tian-Cai Niu et al.   ACS Synthetic Biology

Recombinant Synechococcus elongatus PCC 7942 for improved zeaxanthin production under natural light conditions

(2018) Aditya Sarnaik et al.   Algal Research-Biomass Biofuels and Bioproducts

Predicting the metabolic capabilities of Synechococcus elongatus PCC 7942 adapted to different light regimes

(2018) Jared T. Broddrick et al.   METABOLIC ENGINEERING

Engineering photosynthetic production of L -lysine

(2017) Travis C. Korosh et al.   METABOLIC ENGINEERING

A synthetic, light-driven consortium of cyanobacteria and heterotrophic bacteria enables stable polyhydroxybutyrate production

(2017) Taylor L. Weiss et al.   METABOLIC ENGINEERING

Initial SAM calibration gas experiments on Mars: Quadrupole mass spectrometer results and implications

(2017) Heather B. Franz et al.   PLANETARY AND SPACE SCIENCE

Global metabolic rewiring for improved CO2 fixation and chemical production in cyanobacteria

(2017) Masahiro Kanno et al.   Nature Communications

Improvement of Squalene Production from CO2 in Synechococcus elongatus PCC 7942 by Metabolic Engineering and Scalable Production in a Photobioreactor

(2017) Sun Young Choi et al.   ACS Synthetic Biology

A Genetic Toolbox for Modulating the Expression of Heterologous Genes in the Cyanobacterium Synechocystis sp. PCC 6803

(2017) Bo Wang et al.   ACS Synthetic Biology

The prospects of CRISPR-based genome engineering in the treatment of neurodegenerative disorders

(2017) Jun Wan Shin et al.   Therapeutic Advances in Neurological Disorders

An innovative biologic system for photon-powered myocardium in the ischemic heart

(2017) Jeffrey E. Cohen et al.   Science Advances

Multiplex gene regulation by CRISPR-ddCpf1

(2017) Xiaochun Zhang et al.   Cell Discovery

Understanding Starch Structure: Recent Progress

(2017) Eric Bertoft   Agronomy-Basel

A photoautotrophic platform for the sustainable production of valuable plant natural products from CO2

(2016) Jun Ni et al.   GREEN CHEMISTRY

Complementation of Cobalamin Auxotrophy in Synechococcus sp. Strain PCC 7002 and Validation of a Putative Cobalamin RiboswitchIn Vivo

(2016) Adam A. Pérez et al.   JOURNAL OF BACTERIOLOGY

CRISPR/Cas9 mediated targeted mutagenesis of the fast growing cyanobacterium Synechococcus elongatus UTEX 2973

(2016) Kristen E. Wendt et al.   Microbial Cell Factories

Characterization of Function of the GlgA2 Glycogen/Starch Synthase in Cyanobacterium sp. Clg1 Highlights Convergent Evolution of Glycogen Metabolism into Starch Granule Aggregation

(2016) Derifa Kadouche et al.   PLANT PHYSIOLOGY

Production of C3 platform chemicals from CO2 by genetically engineered cyanobacteria

(2015) Yu Wang et al.   GREEN CHEMISTRY

The plasticity of cyanobacterial metabolism supports direct CO2 conversion to ethylene

(2015) Wei Xiong et al.   Nature Plants