Recent progress in homogeneous electrochemical sensors and their designs and applications

Two-Dimensional Cobalt-Doped Ti3C2 MXene Nanozyme-Mediated Homogeneous Electrochemical Strategy for Pesticides Assay Based on In Situ Generation of Electroactive Substances

(2022) Lei Yu et al.   ANALYTICAL CHEMISTRY

Chemical and Biomolecular Strategies for STING Pathway Activation in Cancer Immunotherapy

(2022) Kyle M. Garland et al.   CHEMICAL REVIEWS

Aptamer–Target Recognition-Promoted Ratiometric Electrochemical Strategy for Evaluating the Microcystin-LR Residue in Fish without Interferences

(2022) Haiyin Li et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Two-Dimensional MnO2 Nanozyme-Mediated Homogeneous Electrochemical Detection of Organophosphate Pesticides without the Interference of H2O2 and Color

(2021) Jiahui Wu et al.   ANALYTICAL CHEMISTRY

A novel miniaturized homogeneous label-free electrochemical biosensing platform combining integrated microelectrode and functional nucleic acids

(2021) Fangming Chen et al.   ANALYTICA CHIMICA ACTA

Universal and Programmable Rolling Circle Amplification-CRISPR/Cas12a-Mediated Immobilization-Free Electrochemical Biosensor

(2021) Min Qing et al.   ANALYTICAL CHEMISTRY

Aptamer Recognition-Driven Homogeneous Electrochemical Strategy for Simultaneous Analysis of Multiple Pesticides without Interference of Color and Fluorescence

(2021) Hongjie Qi et al.   ANALYTICAL CHEMISTRY

Proximity hybridization triggered hybridization chain reaction for label-free electrochemical homogeneous aptasensors

(2021) Xianjiu Liao et al.   TALANTA

DNAzyme-Based Biosensors: Immobilization Strategies, Applications, and Future Prospective

(2021) Shadman Khan et al.   ACS Nano

Near-Infrared Light-Initiated Photoelectrochemical Biosensor Based on Upconversion Nanorods for Immobilization-Free miRNA Detection with Double Signal Amplification

(2021) Mengjiao Hao et al.   ANALYTICAL CHEMISTRY

Highly Sensitive Homogeneous Electrochemiluminescence Biosensor for Alkaline Phosphatase Detection Based on Click Chemistry-Triggered Branched Hybridization Chain Reaction

(2021) Xiaocui Huang et al.   ANALYTICAL CHEMISTRY

High Affinity Dimeric Aptamers Enable Rapid Electrochemical Detection of Wild‐Type and B.1.1.7 SARS‐CoV‐2 in Unprocessed Saliva

(2021) Zijie Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Label-free electrochemical homogeneous detection of the depression marker human apolipoprotein A4 based on proximity hybridization triggered rolling circle amplification

(2021) Xianjiu Liao et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Inorganic Recognizer-Assisted Homogeneous Electrochemiluminescence Determination of Organophosphorus Pesticides via Target-Controlled Emitter Release

(2021) Haiyin Li et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Direct-laser-writing of electrochemiluminescent electrode on glassy carbon for iodide sensing in aqueous solution

(2021) Lei Ge et al.   SENSORS AND ACTUATORS B-CHEMICAL

Modified indium tin oxide electrodes: Electrochemical applications in pharmaceutical, biological, environmental and food analysis

(2021) Hülya Silah et al.   TRAC-TRENDS IN ANALYTICAL CHEMISTRY

Dye sensitized Ti3C2 MXene-based highly sensitive homogeneous photoelectrochemical sensing of phosphate through decomposition of methylene blue-encapsulated zeolitic imidazolate framework-90

(2021) Jiafu Chang et al.   SENSORS AND ACTUATORS B-CHEMICAL

CRISPR/Cas12a-regulated homogeneous electrochemical aptasensor for amplified detection of protein

(2021) Min Qing et al.   SENSORS AND ACTUATORS B-CHEMICAL

Contrary Logic Pair Library, Parity Generator/Checker and Various Concatenated Logic Circuits Engineered by a Label‐Free and Immobilization‐Free Electrochemiluminescence Resonance Energy Transfer System

(2021) Liping Zhu et al.   Small

Redox Host–Guest Nanosensors Installed with DNA Gatekeepers for Immobilization‐Free and Ratiometric Electrochemical Detection of miRNA

(2021) Xiyue Xie et al.   Small Methods

Label-free ratiometric homogeneous electrochemical aptasensor based on hybridization chain reaction for facile and rapid detection of aflatoxin B1 in cereal crops

(2021) Chengxi Zhu et al.   FOOD CHEMISTRY

A novel DNA sensor of homogeneous electrochemical signal amplification strategy

(2020) Qingxia Shu et al.   MICROCHEMICAL JOURNAL

Surface enhanced Raman scattering artificial nose for high dimensionality fingerprinting

(2020) Nayoung Kim et al.   Nature Communications

Label-free and immobilization-free electrochemiluminescent sensing platform for highly sensitive detection of As(III) by combining target-induced strand displacement amplification with polydopamine nanospheres

(2020) Xi Zhu et al.   SENSORS AND ACTUATORS B-CHEMICAL

Ultrasensitive detection of microRNA based on a homogeneous label-free electrochemical platform using G-triplex/methylene blue as a signal generator

(2020) Ling-Li Zhao et al.   ANALYTICA CHIMICA ACTA

Ultrasensitive Homogeneous Electrochemiluminescence Biosensor for Transcription Factor based on Target-modulated Proximity Hybridization and Exonuclease III-powered Recycling Amplification

(2020) Dan Li et al.   ANALYTICAL CHEMISTRY

One-Step Synthesis of Methylene Blue-Encapsulated Zeolitic Imidazolate Framework for Dual-Signal Fluorescent and Homogeneous Electrochemical Biosensing

(2020) Jiafu Chang et al.   ANALYTICAL CHEMISTRY

Dual-output toehold-mediated strand displacement amplification for sensitive homogeneous electrochemical detection of specie-specific DNA sequences for species identification

(2020) Ying Zhang et al.   BIOSENSORS & BIOELECTRONICS

Simple homogeneous electrochemical target-responsive aptasensor based on aptamer bio-gated and porous carbon nanocontainer derived from ZIF-8

(2020) Qian Ren et al.   BIOSENSORS & BIOELECTRONICS

Label-free homogeneous electrochemical biosensor for HPV DNA based on entropy-driven target recycling and hyperbranched rolling circle amplification

(2020) Yinghao He et al.   SENSORS AND ACTUATORS B-CHEMICAL

Precise Capture and Direct Quantification of Tumor Exosomes via a Highly Efficient Dual-Aptamer Recognition-Assisted Ratiometric Immobilization-Free Electrochemical Strategy

(2020) Limin Yang et al.   ANALYTICAL CHEMISTRY

Label-free homogeneous electrochemical detection of MicroRNA based on target-induced anti-shielding against the catalytic activity of two-dimension nanozyme

(2020) Jiahui Wu et al.   BIOSENSORS & BIOELECTRONICS

From signal amplification to restrained background: Magnetic graphene oxide assisted homogeneous electrochemiluminescence aptasensor for highly sensitive detection of okadaic acid

(2020) Weiqiang Yang et al.   SENSORS AND ACTUATORS B-CHEMICAL

Nucleic acid-functionalized metal-organic framework for ultrasensitive immobilization-free photoelectrochemical biosensing

(2020) Xiaojuan Liu et al.   BIOSENSORS & BIOELECTRONICS

Rapid and homogeneous electrochemical detection by fabricating a high affinity bispecific antibody-enzyme complex using two Catcher/Tag systems

(2020) Hayato Kimura et al.   BIOSENSORS & BIOELECTRONICS

Electrode immobilization-free and sensitive electrochemical sensing of thrombin via magnetic nanoparticle-decorated DNA polymers

(2020) Feng Qiu et al.   SENSORS AND ACTUATORS B-CHEMICAL

Nucleic Acid-Functionalized Metal–Organic Framework-Based Homogeneous Electrochemical Biosensor for Simultaneous Detection of Multiple Tumor Biomarkers

(2019) Jiafu Chang et al.   ANALYTICAL CHEMISTRY

Direct Immobilization of Biomolecules Through Magnetic Forces on Ni Electrodes via Ni Nanoparticles: Applications in Electrochemical Biosensors

(2019) Madalina Maria Barsan et al.   ACS Applied Materials & Interfaces

Direct-Laser-Writing of Metal Sulfide-Graphene Nanocomposite Photoelectrode toward Sensitive Photoelectrochemical Sensing

(2019) Lei Ge et al.   ADVANCED FUNCTIONAL MATERIALS

The Exploration of a New Stable G-Triplex DNA and its Novel Function in Electrochemical Biosensing

(2019) Ling-Li Zhao et al.   ANALYTICAL CHEMISTRY

A facile homogeneous electrochemical biosensing strategy based on displacement reaction for intracellular and extracellular hydrogen peroxide detection

(2019) Fengjuan Liu et al.   BIOSENSORS & BIOELECTRONICS

Label-free and immobilization-free photoelectrochemical biosensing strategy using methylene blue in homogeneous solution as signal probe for facile DNA methyltransferase activity assay

(2019) Ting Hou et al.   BIOSENSORS & BIOELECTRONICS

Target-induced conformational switch of DNAzyme for homogeneous electrochemical detection of nereistoxin-related insecticide on an ultramicroelectrode

(2019) Shunbi Xie et al.   SENSORS AND ACTUATORS B-CHEMICAL

Homogeneous Electrochemiluminescence Biosensor for the Detection of RNase A Activity and Its Inhibitor

(2019) Jiancong Ni et al.   ANALYTICAL CHEMISTRY

DNA synergistic enzyme-mediated cascade reaction for homogeneous electrochemical bioassay

(2019) Yaxing Zhang et al.   BIOSENSORS & BIOELECTRONICS

Novel electrochemical immunosensor for sensitive monitoring of cardiac troponin I using antigen–response cargo released from mesoporous Fe3O4

(2019) Ning Ma et al.   BIOSENSORS & BIOELECTRONICS

Immobilization-free, split-mode cathodic photoelectrochemical strategy combined with cascaded amplification for versatile biosensing

(2019) Fang Li et al.   BIOSENSORS & BIOELECTRONICS

Homogenous Electrochemical Method for Ultrasensitive Detection of Tumor Cells Designed by Introduction of Poly(A) Tails onto Cell Membranes

(2019) Ji Zheng et al.   ANALYTICAL CHEMISTRY

Integration of Biofuel Cell-Based Self-Powered Biosensing and Homogeneous Electrochemical Strategy for Ultrasensitive and Easy-To-Use Bioassays of MicroRNA

(2018) Panpan Gai et al.   ACS Applied Materials & Interfaces

A homogeneous electrochemical sensor for Hg2+ determination in environmental water based on the T–Hg2+–T structure and exonuclease III-assisted recycling amplification

(2018) Caili Fu et al.   ANALYST

Direct-laser-writing of three-dimensional porous graphene frameworks on indium-tin oxide for sensitive electrochemical biosensing

(2018) Qing Hong et al.   ANALYST

Truly Immobilization-Free Diffusivity-Mediated Photoelectrochemical Biosensing Strategy for Facile and Highly Sensitive MicroRNA Assay

(2018) Ting Hou et al.   ANALYTICAL CHEMISTRY

Homogeneous and label-free electrochemiluminescence aptasensor based on the difference of electrostatic interaction and exonuclease-assisted target recycling amplification

(2018) Jiancong Ni et al.   BIOSENSORS & BIOELECTRONICS

Enzyme-free homogeneous electrochemical biosensor for DNA assay using toehold-triggered strand displacement reaction coupled with host-guest recognition of Fe 3 O 4 @SiO 2 @β-CD nanocomposites

(2018) Jingjing Jiang et al.   BIOSENSORS & BIOELECTRONICS

Immobilized-free miniaturized electrochemical sensing system for Pb 2+ detection based on dual Pb 2+ -DNAzyme assistant feedback amplification strategy

(2018) Wei Cai et al.   BIOSENSORS & BIOELECTRONICS

Homogeneous electrochemical aptasensor for mucin 1 detection based on exonuclease I-assisted target recycling amplification strategy

(2018) Cuiying Lin et al.   BIOSENSORS & BIOELECTRONICS

Ultrasensitive and versatile homogeneous electrochemical cytosensing platform based on target-induced displacement reaction for “signal-on” bioassay

(2018) Chengcheng Gu et al.   SENSORS AND ACTUATORS B-CHEMICAL

Oligonucleotide-modulated photocurrent enhancement of a tetracationic porphyrin for label-free homogeneous photoelectrochemical biosensing

(2018) Qing Hong et al.   BIOSENSORS & BIOELECTRONICS

Homogeneous electrochemical aptasensor based on a dual amplification strategy for sensitive detection of profenofos residues

(2018) Yancui Jiao et al.   NEW JOURNAL OF CHEMISTRY

Target-induced diffusivity enhancement for rapid and highly sensitive homogeneous electrochemical detection of BLM in human serum

(2018) Jiafu Chang et al.   TALANTA

Label-Free and Immobilization-Free Electrochemical Magnetobiosensor for Sensitive Detection of 5-Hydroxymethylcytosine in Genomic DNA

(2018) Lin Cui et al.   ANALYTICAL CHEMISTRY

Exonuclease-Catalyzed Methylene Blue Releasing and Enriching onto a Dodecanethiol Monolayer for an Immobilization-Free and Highly Sensitive Electrochemical Nucleic Acid Biosensor

(2017) Shufeng Liu et al.   LANGMUIR

A novel label-free homogeneous electrochemical immunosensor based on proximity hybridization-triggered isothermal exponential amplification induced G-quadruplex formation

(2017) Yong Qian et al.   SENSORS AND ACTUATORS B-CHEMICAL

Label-Free Homogeneous Electroanalytical Platform for Pesticide Detection Based on Acetylcholinesterase-Mediated DNA Conformational Switch Integrated with Rolling Circle Amplification

(2017) Xiaojuan Liu et al.   ACS Sensors

Triplex DNA-based Bioanalytical Platform for Highly Sensitive Homogeneous Electrochemical Detection of Melamine

(2017) Xiaojuan Liu et al.   Scientific Reports

An immobilization free DNAzyme based electrochemical biosensor for lead determination

(2016) Yue Tan et al.   ANALYST

Exonuclease I-aided homogeneous electrochemical strategy for organophosphorus pesticide detection based on enzyme inhibition integrated with a DNA conformational switch

(2016) Xiuzhong Wang et al.   ANALYST

Homogeneous Electrochemical Biosensor for Melamine Based on DNA Triplex Structure and Exonuclease III-Assisted Recycling Amplification

(2016) Caili Fu et al.   ANALYTICAL CHEMISTRY

Affinity-Mediated Homogeneous Electrochemical Aptasensor on a Graphene Platform for Ultrasensitive Biomolecule Detection via Exonuclease-Assisted Target-Analog Recycling Amplification

(2016) Lei Ge et al.   ANALYTICAL CHEMISTRY

Versatile and Programmable DNA Logic Gates on Universal and Label-Free Homogeneous Electrochemical Platform

(2016) Lei Ge et al.   ANALYTICAL CHEMISTRY

A signal-on homogeneous electrochemical biosensor for sequence-specific microRNA based on duplex-specific nuclease-assisted target recycling amplification

(2016) Caili Fu et al.   Analytical Methods

Immobilization free electrochemical biosensor for folate receptor in cancer cells based on terminal protection

(2016) Jiancong Ni et al.   BIOSENSORS & BIOELECTRONICS

An immobilization-free electrochemical impedance biosensor based on duplex-specific nuclease assisted target recycling for amplified detection of microRNA

(2016) Jing Zhang et al.   BIOSENSORS & BIOELECTRONICS

Biphasic photoelectrochemical sensing strategy based on in situ formation of CdS quantum dots for highly sensitive detection of acetylcholinesterase activity and inhibition

(2016) Ting Hou et al.   BIOSENSORS & BIOELECTRONICS

Highly sensitive homogeneous electrochemical aptasensor for antibiotic residues detection based on dual recycling amplification strategy

(2016) Xiuzhong Wang et al.   BIOSENSORS & BIOELECTRONICS

A versatile immobilization-free photoelectrochemical biosensor for ultrasensitive detection of cancer biomarker based on enzyme-free cascaded quadratic amplification strategy

(2016) Lei Ge et al.   BIOSENSORS & BIOELECTRONICS

Immobilization-free electrochemical DNA detection with anthraquinone-labeled pyrrolidinyl peptide nucleic acid probe

(2016) Jutatip Kongpeth et al.   TALANTA

Immobilization-free DNA-based homogeneous electrochemical biosensors

(2016) Fang-Ting Zhang et al.   TRAC-TRENDS IN ANALYTICAL CHEMISTRY

Integrated Electrochemical Microsystems for Genetic Detection of Pathogens at the Point of Care

(2015) Kuangwen Hsieh et al.   ACCOUNTS OF CHEMICAL RESEARCH

Graphene-Assisted Label-Free Homogeneous Electrochemical Biosensing Strategy based on Aptamer-Switched Bidirectional DNA Polymerization

(2015) Wenxiao Wang et al.   ACS Applied Materials & Interfaces

Electrochemical Interrogation of Kinetically-Controlled Dendritic DNA/PNA Assembly for Immobilization-Free and Enzyme-Free Nucleic Acids Sensing

(2015) Feng Xuan et al.   ACS Nano

Hybridization-induced Ag(i) dissociation from an immobilization-free and label-free hairpin DNA: toward a novel electronic monitoring platform

(2015) Ai-Li Sun et al.   ANALYST

A highly sensitive homogeneous electrochemical assay for alkaline phosphatase activity based on single molecular beacon-initiated T7 exonuclease-mediated signal amplification

(2015) Lianfang Zhang et al.   ANALYST

Ultraselective Homogeneous Electrochemical Biosensor for DNA Species Related to Oral Cancer Based on Nicking Endonuclease Assisted Target Recycling Amplification

(2015) Yue Tan et al.   ANALYTICAL CHEMISTRY

Exonuclease-Catalyzed Target Recycling Amplification and Immobilization-free Electrochemical Aptasensor

(2015) Yue Tan et al.   ANALYTICAL CHEMISTRY

Label-Free and Enzyme-Free Homogeneous Electrochemical Biosensing Strategy Based on Hybridization Chain Reaction: A Facile, Sensitive, and Highly Specific MicroRNA Assay

(2015) Ting Hou et al.   ANALYTICAL CHEMISTRY

Homogeneous Electrochemical Strategy for Human Telomerase Activity Assay at Single-Cell Level Based on T7 Exonuclease-Aided Target Recycling Amplification

(2015) Xiaojuan Liu et al.   ANALYTICAL CHEMISTRY

Ultrasensitive homogeneous electrochemical strategy for DNA methyltransferase activity assay based on autonomous exonuclease III-assisted isothermal cycling signal amplification

(2015) Wei Li et al.   BIOSENSORS & BIOELECTRONICS

Homogeneous electrochemical aptamer-based ATP assay with signal amplification by exonuclease III assisted target recycling

(2013) Shufeng Liu et al.   CHEMICAL COMMUNICATIONS