Toxicity of pesticides widely applied on soybean cultivation: Synergistic effects of fipronil, glyphosate and imidacloprid in HepG2 cells

From street to lab: in vitro hepatotoxicity of buphedrone, butylone and 3,4-DMMC

(2021) Rita Roque Bravo et al.   ARCHIVES OF TOXICOLOGY

Comparison of the toxicity of pure compounds and commercial formulations of imidacloprid and acetamiprid on HT-29 cells: Single and mixture exposure

(2021) Merve Baysal et al.   FOOD AND CHEMICAL TOXICOLOGY

Micronucleus Formation Induced by Glyphosate and Glyphosate-Based Herbicides in Human Peripheral White Blood Cells

(2021) Károly Nagy et al.   Frontiers in Public Health

4-Fluoromethamphetamine (4-FMA) induces in vitro hepatotoxicity mediated by CYP2E1, CYP2D6, and CYP3A4 metabolism

(2021) Rita Roque Bravo et al.   TOXICOLOGY

Effects of imidacloprid on viability and increase of reactive oxygen and nitrogen species in HepG2 cell line

(2021) Anilda Rufino de Jesus Santos Guimarães et al.   TOXICOLOGY MECHANISMS AND METHODS

“Modern agriculture” transfers many pesticides to watercourses: a case study of a representative rural catchment of southern Brazil

(2020) José Augusto Monteiro de Castro Lima et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Enhanced cytotoxicity of imidacloprid by biotransformation in isolated hepatocytes and perfused rat liver

(2020) Paulo F.V. Bizerra et al.   PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY

The global environmental hazard of glyphosate use

(2020) Federico Maggi et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Garlic and allopurinol attenuate hepatic apoptosis induced by fipronil in male albino rats

(2019) Amira A. Sayed et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Systematic review of comparative studies assessing the toxicity of pesticide active ingredients and their product formulations

(2019) Károly Nagy et al.   ENVIRONMENTAL RESEARCH

Emerging club drugs: 5-(2-aminopropyl)benzofuran (5-APB) is more toxic than its isomer 6-(2-aminopropyl)benzofuran (6-APB) in hepatocyte cellular models

(2019) Rita Roque Bravo et al.   ARCHIVES OF TOXICOLOGY

Comparative cyto- and genotoxicity assessment of glyphosate and glyphosate-based herbicides in human peripheral white blood cells

(2019) Károly Nagy et al.   ENVIRONMENTAL RESEARCH

Ethanol addictively enhances the in vitro cardiotoxicity of cocaine through oxidative damage, energetic deregulation, and apoptosis

(2018) Maria João Martins et al.   ARCHIVES OF TOXICOLOGY

Single and joint toxicity assessment of four currently used pesticides to zebrafish ( Danio rerio ) using traditional and molecular endpoints

(2018) Yanhua Wang et al.   CHEMOSPHERE

Chronic effects of an environmentally-relevant, short-term neonicotinoid insecticide pulse on four aquatic invertebrates

(2018) Melanie Raby et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Investigation of the genotoxic and cytotoxic effects of widely used neonicotinoid insecticides in HepG2 and SH-SY5Y cells

(2018) Mine Şenyildiz et al.   TOXICOLOGY AND INDUSTRIAL HEALTH

Effects of low doses of glyphosate on DNA damage, cell proliferation and oxidative stress in the HepG2 cell line

(2017) Vilena Kašuba et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

DNA damage and methylation induced by glyphosate in human peripheral blood mononuclear cells ( in vitro study)

(2017) Marta Kwiatkowska et al.   FOOD AND CHEMICAL TOXICOLOGY

In vitro hepatotoxicity of ‘Legal X’: the combination of 1-benzylpiperazine (BZP) and 1-(m-trifluoromethylphenyl)piperazine (TFMPP) triggers oxidative stress, mitochondrial impairment and apoptosis

(2016) Diana Dias da Silva et al.   ARCHIVES OF TOXICOLOGY

Concerns over use of glyphosate-based herbicides and risks associated with exposures: a consensus statement

(2016) John Peterson Myers et al.   Environmental Health

Effects of Neonicotinoid Pesticide Exposure on Human Health: A Systematic Review

(2016) Andria M. Cimino et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Toxicogenetic effects of low concentrations of the pesticides imidacloprid and sulfentrazone individually and in combination in in vitro tests with HepG2 cells and Salmonella typhimurium

(2015) Jaqueline Bianchi et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Comparative effects of fipronil and its metabolites sulfone and desulfinyl on the isolated rat liver mitochondria

(2015) Marco A. Tavares et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Firpronil induced spermotoxicity is associated with oxidative stress, DNA damage and apoptosis in male rats

(2015) Saleem Khan et al.   PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY

Low concentrations of cylindrospermopsin induce increases of reactive oxygen species levels, metabolism and proliferation in human hepatoma cells (HepG2)

(2015) Samuel Liebel et al.   TOXICOLOGY IN VITRO

Hepatotoxicity of piperazine designer drugs: Comparison of different in vitro models

(2015) D. Dias-da-Silva et al.   TOXICOLOGY IN VITRO

Effect of fipronil on energy metabolism in the perfused rat liver

(2015) Hyllana Catarine Dias de Medeiros et al.   TOXICOLOGY LETTERS

In Vitro Genotoxicity of Fipronil Sister Chromatid Exchange, Cytokinesis Block Micronucleus Test, and Comet Assay

(2014) Ayla Çelik et al.   DNA AND CELL BIOLOGY

Systemic insecticides (neonicotinoids and fipronil): trends, uses, mode of action and metabolites

(2014) N. Simon-Delso et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Evaluation of imidacloprid-induced neurotoxicity in male rats: A protective effect of curcumin

(2014) Milindmitra Lonare et al.   NEUROCHEMISTRY INTERNATIONAL

Major Pesticides Are More Toxic to Human Cells Than Their Declared Active Principles

(2014) Robin Mesnage et al.   Biomed Research International

Therapeutic Concentrations of Mitoxantrone Elicit Energetic Imbalance in H9c2 Cells as an Earlier Event

(2013) Luciana Grazziotin Rossato et al.   Cardiovascular Toxicology

Mixtures of 3,4-methylenedioxymethamphetamine (ecstasy) and its major human metabolites act additively to induce significant toxicity to liver cells when combined at low, non-cytotoxic concentrations

(2013) Diana Dias da Silva et al.   JOURNAL OF APPLIED TOXICOLOGY

The risky cocktail: what combination effects can we expect between ecstasy and other amphetamines?

(2012) Diana Dias da Silva et al.   ARCHIVES OF TOXICOLOGY

Glyphosate-induced stiffening of HaCaT keratinocytes, a Peak Force Tapping study on living cells

(2012) Celine Heu et al.   JOURNAL OF STRUCTURAL BIOLOGY

The hormesis effect of BDE-47 in HepG2 cells and the potential molecular mechanism

(2012) Liulin Wang et al.   TOXICOLOGY LETTERS

The role of mitochondria in apoptosis

(2011) Seon-Yong Jeong et al.   BMB Reports

Fipronil is a powerful uncoupler of oxidative phosphorylation that triggers apoptosis in human neuronal cell line SHSY5Y

(2011) Cyril Vidau et al.   NEUROTOXICOLOGY

Structural isomerization of synephrine influences its uptake and ensuing glutathione depletion in rat-isolated cardiomyocytes

(2010) Luciana Grazziotin Rossato et al.   ARCHIVES OF TOXICOLOGY

Combining the in vivo comet and micronucleus assays: a practical approach to genotoxicity testing and data interpretation

(2009) Marie Z. Vasquez   MUTAGENESIS

Glutamate-activated chloride channels: Unique fipronil targets present in insects but not in mammals

(2009) Toshio Narahashi et al.   PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY

Glyphosate-based herbicides are toxic and endocrine disruptors in human cell lines

(2009) Céline Gasnier et al.   TOXICOLOGY

Determination of glyphosate, glyphosate metabolites, and glufosinate in human serum by gas chromatography–mass spectrometry

(2008) M MOTOJYUKU et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Fipronil-induced disruption of thyroid function in rats is mediated by increased total and free thyroxine clearances concomitantly to increased activity of hepatic enzymes

(2008) Julien Leghait et al.   TOXICOLOGY