Article
Agriculture, Dairy & Animal Science
Zhongchang Hu, Jian Wu, Lihong Qin, Haiguo Jin, Yang Lv, Ran Zhang, Cheng Xiao, Yang Cao, Yumin Zhao
Summary: ALDH1A1 plays a significant regulatory role in the differentiation of preadipocyte cells in Yan Yellow Cattle. Modulation of ALDH1A1 gene expression can affect acetaldehyde oxidation and adipocyte development, with changes in lipid accumulation and triglyceride production observed in mature adipocytes. The protein expression levels of ALDH1A1 and adipogenic factors corresponded to the mRNA levels, indicating an important role of ALDH1A1 in fat cell growth and development.
ANIMAL BIOTECHNOLOGY
(2021)
Article
Marine & Freshwater Biology
Wenli Guo, Beibei Gao, Xiaoqian Zhang, Quanzhong Ren, Dizhi Xie, Junping Liang, Hui Li, Xianfeng Wang, Yuru Zhang, Sijin Liu, Guoxing Nie
Summary: Cadmium, as one of the most prevalent environmental contaminants, poses a threat to ecosystems due to its high persistence and bioavailability. This study revealed that environmental exposure to Cadmium disrupts lipid metabolism in fish, especially the metabolism of triglycerides and cholesterol. These findings suggest that environmental factors could contribute to the prevalence of nonalcoholic fatty-liver disease in aquaculture.
AQUATIC TOXICOLOGY
(2022)
Article
Agriculture, Dairy & Animal Science
Zhongchang Hu, Jian Wu, Lihong Qin, Haiguo Jin, Yang Cao, Yumin Zhao
Summary: The study revealed that the expression levels of the IGFBP7 gene are specifically regulated during the adipocyte differentiation in Yan Yellow Cattle. Overexpression and RNA interference of the IGFBP7 gene had significant effects on lipid accumulation and triglyceride production in mature adipocytes.
ANIMAL BIOTECHNOLOGY
(2021)
Article
Genetics & Heredity
Yanli Wang, Xin Li, Yang Cao, Cheng Xiao, Yu Liu, Haiguo Jin, Yang Cao
Summary: ACAA1 plays a crucial role in sheep preadipocyte differentiation, with deficiency increasing lipid accumulation and promoting differentiation, while overexpression inhibiting adipogenesis.
FRONTIERS IN GENETICS
(2021)
Article
Multidisciplinary Sciences
Xiufei Cao, Wei Fang, Xueshan Li, Xiuneng Wang, Kangsen Mai, Qinghui Ai
Summary: LDLR plays a crucial role in hepatic triglyceride accumulation in fish, and its expression is directly or indirectly regulated by SREBP2. SREBP2 can directly activate LDLR transcription and indirectly regulate LDLR through increasing the transcription of lncRNA LDLR-AS. Mechanism analysis revealed that LDLR-AS acts as an RNA scaffold to stabilize LDLR mRNA.
Article
Multidisciplinary Sciences
Xu Xiao, Youngjae Kim, Beatriz Romartinez-Alonso, Kristupas Sirvydis, Daniel S. Ory, John W. R. Schwabe, Michael E. Jung, Peter Tontonoz
Summary: Aster proteins mediate nonvesicular plasma membrane to endoplasmic reticulum cholesterol transport, with 20 alpha-hydroxycholesterol and U18666A identified as potential small molecule modulators. However, they target other sterol homeostatic proteins, limiting their utility.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Food Science & Technology
Nisreen Faizo, Chandrakala Aluganti Narasimhulu, Anna Forsman, Shibu Yooseph, Sampath Parthasarathy
Summary: The study utilized RNA sequencing to investigate the impact of exposure to peroxidized linoleic acid on cellular processes, uncovering alterations in lipid metabolic pathways, detoxification mechanisms, and suppression of oxidative phosphorylation. These findings provide insights into the effects of 13-HPODE on cellular processes and propose potential therapeutic strategies for LOOH-related pathologies.
Review
Biochemistry & Molecular Biology
Yasmin Alaby Martins Ferreira, Giovana Jamar, Debora Estadella, Luciana Pellegrini Pisani
Summary: High-fat diet disrupts adipose tissue function and AMPK regulation, while carotenoids can activate AMPK and improve adipogenesis. Clinical trials are needed to confirm the long-term effects of carotenoids on the AMPK pathway in obesity treatment.
Article
Medicine, Research & Experimental
Yuke Wang, Ying Pan, Mirong Hou, Rongsiqing Luo, Jiawei He, Fan Lin, Xiaofang Xia, Ping Li, Chunxiang He, Pan He, Shaowu Cheng, Zhenyan Song
Summary: This study investigated the effects of Danggui Shaoyao San (DSS) on lipid metabolism in hyperlipidemia using a zebrafish model. The results showed that DSS can ameliorate lipid metabolic disorders in hyperlipidemia by modulating the PPAR signaling pathway, leading to a reduction in lipid accumulation within the body.
BIOMEDICINE & PHARMACOTHERAPY
(2023)
Article
Genetics & Heredity
Yan Zhao, L. Filipe C. Castro, Oscar Monroig, Xiaojuan Cao, Yonghua Sun, Jian Gao
Summary: This study generated a zebrafish mutant lacking ppar γ with CRISPR/Cas9 technology and investigated its regulatory network. The deletion of ppar γ protected against high-fat diet-induced lipid deposition and involved protein kinases related to lipid metabolism.
FUNCTIONAL & INTEGRATIVE GENOMICS
(2022)
Article
Genetics & Heredity
Xitong Zhao, Huatao Liu, Yongjie Pan, Yibing Liu, Fengxia Zhang, Hong Ao, Jibin Zhang, Kai Xing, Chuduan Wang
Summary: Preadipocyte differentiation and its related gene clusters were studied in this research, using preadipocytes isolated from subcutaneous adipose tissue of pigs. Three co-expression modules (blue, magenta, and brown) were identified as critical during preadipocyte differentiation. Angiopoietin-like 4 (ANGPTL4) was identified as a key regulator of preadipocyte differentiation and lipid metabolism.
FRONTIERS IN GENETICS
(2022)
Article
Gastroenterology & Hepatology
Sarra Smati, Arnaud Polizzi, Anne Fougerat, Sandrine Ellero-Simatos, Yuna Blum, Yannick Lippi, Marion Regnier, Alexia Laroyenne, Marine Huillet, Muhammad Arif, Cheng Zhang, Frederic Lasserre, Alain Marrot, Talal Al Saati, JingHong Wan, Caroline Sommer, Claire Naylies, Aurelie Batut, Celine Lukowicz, Tiffany Fougeray, Blandine Tramunt, Patricia Dubot, Lorraine Smith, Justine Bertrand-Michel, Nathalie Hennuyer, Jean-Philippe Pradere, Bart Staels, Remy Burcelin, Francoise Lenfant, Jean-Francois Arnal, Thierry Levade, Laurence Gamet-Payrastre, Sandrine Lagarrigue, Nicolas Loiseau, Sophie Lotersztajn, Catherine Postic, Walter Wahli, Christophe Bureau, Maeva Guillaume, Adil Mardinoglu, Alexandra Montagner, Pierre Gourdy, Herve Guillou
Summary: The study found that different diets induced more severe NAFLD in male mice, characterized by lipid accumulation and inflammation/fibrosis. Sex-biased hepatic gene signatures showed different responses to various dietary challenges, with Peroxisome proliferator-activated receptor alpha (PPAR alpha) playing a key role in gender-specific and NAFLD pathophysiology.
Article
Cardiac & Cardiovascular Systems
Ren Zhang
Summary: Elevated triglyceride and reduced high-density lipoprotein-cholesterol plasma levels are risk factors for atherosclerosis and cardiovascular disease. By inhibiting lipoprotein lipase and endothelial lipase, Angiopoietin-like 3 (ANGPTL3) plays a role in regulating plasma triglyceride and HDL-C levels. Angiopoietin-like 3 inhibition of LPL requires complex formation with Angiopoietin-like 8, which is not required for its inhibition of EL. By disrupting or precluding the ANGPTL3-8 complex formation, ANGPTL8 antagonism can increase LPL activity while decreasing EL activity, leading to reduced plasma triglyceride and increased HDL-C levels.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Article
Environmental Sciences
Yao Zhao, Zhen Qin, Zhuizui Huang, Zhiwei Bao, Ting Luo, Yuanxiang Jin
Summary: This study demonstrates that polyethylene microplastics have significant effects on the microbiome and metabolism of larval zebrafish, including changes in microbial community, alterations in metabolites levels, and variations in gene transcription levels.
ENVIRONMENTAL POLLUTION
(2021)
Article
Biochemistry & Molecular Biology
Magdalena J. M. Marschall, Robert Ringseis, Denise K. Gessner, Sarah M. Grundmann, Erika Most, Gaiping Wen, Garima Maheshwari, Holger Zorn, Klaus Eder
Summary: The study demonstrates that ecdysterone supplementation does not reduce lipid levels in the liver and plasma of lean and obese Zucker rats.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Chemistry, Multidisciplinary
Ao Yu, Wangtao Long, Longtao Zhu, Yinan Zhao, Ping Peng, Fang -Fang Li
Summary: Researchers have successfully synthesized and characterized Fe/N/F-tridoped CNTs catalysts, which show excellent performance in Zn-air batteries, with high open-circuit voltage, peak power density, and long-term stability, outperforming the benchmark Pt/C catalyst.
CHINESE CHEMICAL LETTERS
(2023)
Article
Chemistry, Multidisciplinary
Yirong Zhang, Wenqian Huang, Minjie Li, Fangfang Li, Lingxiangyu Li, Monika Mortimer, Liang-Hong Guo
Summary: With the widespread use of nanotechnology in the food industry, humans are increasingly exposed to engineered nanoparticles (NPs) in food. These NPs interact with beneficial bacteria in the human digestive tract, affecting their growth and triggering biotransformation. This study investigated the effects of different NPs on Streptococcus salivarius K12, a beneficial bacterium in the oral cavity, and observed changes in gene expression and NP transformations. The results suggest that food-related NPs can impact the competitiveness of beneficial bacteria and their activities influence the fate and toxicity of NPs in the digestive tract.
ENVIRONMENTAL SCIENCE-NANO
(2023)
Article
Chemistry, Physical
Yu Lin, Fangfang Li, Xiaoqing Li, Hongwei Zhao, Gang Liu
Summary: In order to recycle wastes and develop renewable energy, researchers have focused on converting biowastes into porous carbon for supercapacitors. A one-step strategy of synchronous activation and support has been designed to prepare N-, O-, and S-codoped mesoporous hollow biochar nanocages (BNC-700). The BNC-700 exhibits an interconnected porous structure and a unique two-dimensional (2D) multilayer wall/three-dimensional (3D) hollow nanocage structure with abundant active heteroatoms and edge defects. The assembled supercapacitor based on BNC-700 shows a considerable energy density of 37.4 Wh kg-1 at 212 W kg-1 and cycling stability of 99.5% after 15,000 cycles.
ACS APPLIED ENERGY MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Ao Yu, Yinan Zhao, Wei Zhang, Wenhao Yang, Longtao Zhu, Ping Peng, Fang-Fang Li, Yang Yang
Summary: This article presents a novel bi-directional electrolysis strategy for synthesizing oxygen-rich mesoporous carbons (OMCs) with adjustable pore sizes and oxygen-bearing functional groups from CO2, and demonstrates the advantages of OMCs in ZICs through experimental results. The designed OMCs exhibit remarkable energy density and cycling performance, and show high capacitance in flexible ZICs.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Article
Environmental Sciences
Zhi Li, Tingyu Lu, Minjie Li, Monika Mortimer, Liang-Hong Guo
Summary: This review discusses the ecological impacts of antibiotics on fish and zooplankton, primarily focusing on their effects on health and gut microbiota. High concentrations of antibiotics can induce acute effects, but even environmentally relevant levels can disrupt physiological homeostasis and development. The correlation and causality of changes in gut microbiota to host physiology are not straightforward and more data are needed for ecological risk assessment.
Article
Environmental Sciences
Jinjian Ding, Yan Sun, Monika Mortimer, Liang-Hong Guo, Fangxing Yang
Summary: The residues of two widely used chiral fungicides, Metalaxyl (MET) and myclobutanil (MYC), were detected in the dietary food and urine of residents in an Eastern China city. The study found variations in residue levels of MET and MYC in different food items, as well as differences in urinary excretion between different populations. The research also showed that children have higher dietary intake but lower urinary excretion rates, potentially leading to higher body burdens.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2023)
Review
Chemistry, Physical
Jianpei Feng, Chun Hong Mak, Li Yu, Bin Han, Hsin-Hui Shen, Shella Permatasari Santoso, Mingjian Yuan, Fang-Fang Li, Haisheng Song, Juan Carlos Colmenares, Hsien-Yi Hsu
Summary: Organic-inorganic halide perovskites (OIHPs) have attracted extensive attention as novel photocatalyst materials in various applications due to their excellent photophysical properties. To improve the air-water stability and photocatalytic performance of OIHPs for practical applications, it is crucial to study modification strategies and interfacial interaction mechanisms. This review summarizes the current progress in the development and photocatalytic fundamentals of OIHPs, and elucidates the structural modification strategies and interfacial mechanisms using various characterization methods. Furthermore, it presents various photocatalytic applications of OIHPs, including hydrogen evolution, CO2 reduction, pollutant degradation, and photocatalytic conversion of organic matter.
Article
Chemistry, Inorganic & Nuclear
Xinyi Zhou, Yang-Rong Yao, Yajing Hu, Le Yang, Shaoting Yang, Yilu Zhang, Qianyan Zhang, Ping Peng, Peng Jin, Fang-Fang Li
Summary: The reactivity of open-shell Gd@C-2v-C-82 with different charge states towards benzyl bromide was investigated. It was found that [Gd@C-2v-C-82](3-) exhibited higher activity compared to Gd@C-2v-C-82 and [Gd@C-2v-C-82](-). Structural characterizations revealed the formation of isomeric benzyl monoadducts of Gd@C-2v-C-82, each containing mirror-symmetric enantiomers. Furthermore, the addition of the benzyl group and its specific position led to distinct electrochemical behavior of the products, different from the parent Gd@C-2v-C-82. Theoretical studies supported these observations by demonstrating that only [Gd@C-2v-C-82](3-) had a HOMO energy level that matched well with the LUMO energy level of the PhCH2 radical, providing a rationalization for the observed significantly different reactivity.
Article
Chemistry, Multidisciplinary
Pengpeng Li, Fangfang Li, Fu Su
Summary: In this work, g-C3N4/WO3 was doped with 2-aminobenthiol (ABT) small molecules through calcination to enhance visible light catalytic ability. Characterization methods such as SEM, TEM, and XPS were used to investigate the properties of the materials. UV diffuse reflection spectroscopy revealed a significant enhancement in the absorption capacity of 1 wt% ABT/CN in the visible region after ABT doping. The 1 wt% ABT-CN/WO3 catalyst exhibited a stronger photocatalytic performance in the degradation of tetracycline (TC) under visible light irradiation compared to other materials.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Xin Chang, Xue-Tao Liu, Fangfang Li, Yuhong Yang, Lung Wa Chung, Chun-Jiang Wang
Summary: A series of benzofulvenes without electron-withdrawing substituents were used as 2π-type dipolarophiles in Cu(i)-catalyzed asymmetric 1,3-dipolar cycloaddition reactions. The non-benzenoid aromatic characteristic of benzofulvenes served as a key driving force for their activation. The methodology allowed for the synthesis of multi-substituted chiral spiro-pyrrolidine derivatives with exclusive chemo-/regioselectivity and high to excellent stereoselectivity.
Article
Chemistry, Physical
Ruiyao Xu, Beibei Xu, Xiaomeng You, Danni Shao, Guoliang Gao, Fangfang Li, Xue-Lu Wang, Ye-Feng Yao
Summary: The photocatalytic production of hydrogen via single-atom catalysts (SACs) has gained attention for the environmentally friendly hydrogen production. However, a facile method of fabricating SACs without aggregation of active atoms remains undeveloped. This study proposes a novel photochemical reaction in a frozen precursor solution to prepare SACs with active Pd atoms on g-C3N4 supports. The results show that the proposed method can be universally applied and provide higher photocatalytic hydrogen production performance compared to the non-frozen control group.
JOURNAL OF MATERIALS CHEMISTRY A
(2023)
Article
Chemistry, Physical
Yu Lin, Fangfang Li, Xiaoqing Li, Hongwei Zhao, Gang Liu
Summary: In order to recycle wastes and develop renewable energy, researchers have focused on converting biowastes into porous carbon for supercapacitors. A one-step strategy involving the thermal decomposition of a multifunctional template (magnesium acetate) is designed to prepare N, O, and S-codoped mesoporous hollow biochar nanocages. The assembled supercapacitor exhibits a high energy density and cycling stability, making it a potential application for advanced energy storage devices.
ACS APPLIED ENERGY MATERIALS
(2023)
Article
Chemistry, Inorganic & Nuclear
Fu-Kai Yang, Yue Fang, Fang-Fang Li, Wei-Li Qu, Chao Deng
Summary: A ternary alloy catalyst with a special 3D structure, PdCuSn Ns/C, has been synthesized, which shows improved electrocatalytic performance for formic acid fuel cells by changing the electronic structure of Pd and reducing the use of precious metals and production cost.
DALTON TRANSACTIONS
(2023)
Article
Environmental Sciences
Toshimi Nakajima, Mao Kuragano, Makoto Yamada, Ryo Sugimoto
Summary: This study compared the contribution of submarine groundwater discharge (SGD) to river nutrient budgets at nearshore and embayment scales, and found that SGD-derived nutrients become more important at larger spatial scales.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Fan Liu, Lei Zhang, Chongyang Zhang, Ziguang Chen, Jingguang Li
Summary: NO2 emissions from wall-mounted gas stoves used for household heating have become a significant source of indoor pollution in Chinese urban areas. The high indoor concentration of NO2 poses potential health risks to residents. It is urgently necessary to establish relevant regulations and implement emission reduction technologies to reduce NO2 emissions from wall-mounted gas stoves.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Letter
Environmental Sciences
Hans Peter H. Arp, Raoul Wolf, Sarah E. Hale, Sivani Baskaran, Juliane Gluege, Martin Scheringer, Xenia Trier, Ian T. Cousins, Harrie Timmer, Roberta Hofman-Caris, Anna Lennquist, Andre D. Bannink, Gerard J. Stroomberg, Rosa M. A. Sjerps, Rosa Montes, Rosario Rodil, Jose Benito Quintana, Daniel Zahn, Herve Gallard, Tobias Mohr, Ivo Schliebner, Michael Neumann
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Philomina Onyedikachi Peter, Binessi Edouard Ifon, Francois Nkinahamira, Kayode Hassan Lasisi, Jiangwei Li, Anyi Hu, Chang-Ping Yu
Summary: This study investigates the relationship between dissolved organic matter (DOM) and Rare Earth Elements (REEs) in sediments from Yundang Lagoon, China. The results show four distinct fluorescent components, with protein-like substances being the most prevalent. Additionally, the total fluorescence intensity and LREE concentrations exhibit a synchronized increase from Outer to Inner to Songbai Lake core sediments. The findings demonstrate a strong correlation between DOM content and pollution levels.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Surya Gupta, Pasquale Borrelli, Panos Panagos, Christine Alewell
Summary: The objective of this study is to incorporate soil hydraulic properties into the erodibility factor (K) of USLE-type models. By modifying and improving the existing equations for soil texture and permeability, the study successfully included information on saturated hydraulic conductivity (Ksat) into the calculation of K factor. Using the Random Forest machine learning algorithm, two independent K factor maps with different spatial resolutions were generated. The results show that the decrease in K factor values has a positive impact on the modeling of soil erosion rates.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Jesmin Akter, Wendy J. M. Smith, Yawen Liu, Ilho Kim, Stuart L. Simpson, Phong Thai, Asja Korajkic, Warish Ahmed
Summary: The choice of workflow in wastewater surveillance has a significant impact on SARS-CoV-2 concentrations, while having minimal effects on HF183 and no effect on HAdV 40/41 concentrations. Certain components in the workflow can be interchangeable, but factors such as buffer type, chloroform, and homogenization speed can affect the recovery of viruses and bacteria.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Yu Luo, Xueting Yang, Diwei Wang, Hongmei Xu, Hongai Zhang, Shasha Huang, Qiyuan Wang, Ningning Zhang, Junji Cao, Zhenxing Shen
Summary: Atmospheric PM2.5, which can generate reactive oxygen species (ROS), is associated with cardiorespiratory morbidity and mortality. The study found that both the mass concentration of PM2.5 and the DTT activity were higher during the heating season than during the nonheating season. Combustion sources were the primary contributors to DTT activity during the heating season, while secondary formation dominated during the nonheating season. The study also revealed that biomass burning had the highest inherent oxidation potential among all sources investigated.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Erin L. Murphy, Leah R. Gerber, Chelsea M. Rochman, Beth Polidoro
Summary: Plastic pollution has devastating consequences for marine organisms. This study uses a trait-based framework to develop a vulnerability index for marine mammals, seabirds, and sea turtles in Hawai'i. The index ranks 63 study species based on their vulnerability to macroplastic pollution, providing valuable information for species monitoring and management priorities.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Kenji Maurice, Amelia Bourceret, Sami Youssef, Stephane Boivin, Liam Laurent-Webb, Coraline Damasio, Hassan Boukcim, Marc-Andre Selosse, Marc Ducousso
Summary: Growing pressure from climate change and agricultural land use is destabilizing soil microbial community interactions. Little is known about microbial community resistance and adaptation to disturbances, hindering our understanding of recovery latency and implications for ecosystem functioning. This study found that anthropic disturbance and natural disturbance have different effects on the topology and stability of soil microbial networks.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Yunhao Li, Yali Feng, Haoran Li, Yisong Yao, Chenglong Xu, Jinrong Ju, Ruiyu Ma, Haoyu Wang, Shiwei Jiang
Summary: Deep-sea mining poses a serious threat to marine ecosystems and human health by disturbing sediment and transmitting metal ions through the food chain. This study developed a new regenerative adsorption material, OMN@SA, which effectively removes metal ions. The adsorption mechanism and performance of the material for metal ion fixation were investigated.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Antonio Medici, Margherita Lavorgna, Marina Isidori, Chiara Russo, Elena Orlo, Giovanni Luongo, Giovanni Di Fabio, Armando Zarrelli
Summary: Valsartan, a widely used antihypertensive drug, has been detected in high concentrations in surface waters due to its unchanged excretion and incomplete degradation in wastewater treatment plants. This study investigated the degradation of valsartan and identified 14 degradation byproducts. The acute and chronic toxicity of these byproducts were evaluated in key organisms in the freshwater trophic chain.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Jiang Lin, Lianbao Chi, Qing Yuan, Busu Li, Mingbao Feng
Summary: This study investigated the photodegradation behavior and product formation of two representative pharmaceuticals in simulated estuary water. The study found that the formed transformation products of these pharmaceuticals have potential toxicity on marine organisms, including oxidative stress and damage to cellular components.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Hua Fang, Dongdong Jiang, Ye He, Siyi Wu, Yuehong Li, Ziqi Zhang, Haoting Chen, Zixin Zheng, Yan Sun, Wenxiang Wang
Summary: This study revealed that exposure to lower levels of air pollutants led to decreased pregnancy rates, with PM10, NO2, SO2, and CO emerging as the four most prominent pollutants. Individuals aged 35 and above exhibited heightened susceptibility to pollutants.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Ali Shaan Manzoor Ghumman, Rashid Shamsuddin, Amin Abbasi, Mohaira Ahmad, Yoshiaki Yoshida, Abdul Sami, Hamad Almohamadi
Summary: In this study, inverse vulcanized polysulfides (IVP) were synthesized by reacting molten sulfur with 4-vinyl benzyl chloride, and then functionalized using N-methyl D-glucamine (NMDG). The functionalized IVP showed a high mercury adsorption capacity and a machine learning model was developed to predict the amount of mercury removed. Furthermore, the functionalized IVP can be regenerated and reused, providing a sustainable and cost-effective adsorbent.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Rita Bonfiglio, Renata Sisto, Stefano Casciardi, Valeria Palumbo, Maria Paola Scioli, Erica Giacobbi, Francesca Servadei, Gerry Melino, Alessandro Mauriello, Manuel Scimeca
Summary: This study investigated the presence of aluminum in human colon cancer samples and its potential association with biological processes involved in cancer progression. Aluminum was found in tumor areas of 24% of patients and was associated with epithelial to mesenchymal transition (EMT) and cell death. Additional analyses revealed higher tumor mutational burden and mutations in genes related to EMT and apoptosis in aluminum-positive colon cancers. Understanding the molecular mechanisms of aluminum toxicity may improve strategies for the management of colon cancer patients.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)