Medium Chain Fatty Acids Are Selective Peroxisome Proliferator Activated Receptor (PPAR) γ Activators and Pan-PPAR Partial Agonists

Antidiabetic actions of a non-agonist PPARγ ligand blocking Cdk5-mediated phosphorylation

(2011) Jang Hyun Choi et al.   NATURE

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARγ by Cdk5

(2010) Jang Hyun Choi et al.   NATURE

Identification of a Physiologically Relevant Endogenous Ligand for PPARα in Liver

(2009) Manu V. Chakravarthy et al.   CELL

Medium-chain fatty acids: Functional lipids for the prevention and treatment of the metabolic syndrome

(2009) Koji Nagao et al.   PHARMACOLOGICAL RESEARCH

Gaining ligand selectivity in thyroid hormone receptors via entropy

(2009) L. Martinez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fat and Beyond: The Diverse Biology of PPARγ

(2008) Peter Tontonoz et al.   Annual Review of Biochemistry

Atomic structure of mutant PPARγ LBD complexed with 15d-PGJ2: Novel modulation mechanism of PPARγ/RXRα function by covalently bound ligands

(2008) Tsuyoshi Waku et al.   FEBS LETTERS

Regulation of adipogenesis by medium-chain fatty acids in the absence of hormonal cocktail☆

(2008) Jeong-Yeh Yang et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

The MX2 macromolecular crystallography beamline: a wiggler X-ray source at the LNLS

(2008) Beatriz G. Guimarães et al.   JOURNAL OF SYNCHROTRON RADIATION

Structure of SF-1 Bound by Different Phospholipids: Evidence for Regulatory Ligands

(2008) Elena P. Sablin et al.   MOLECULAR ENDOCRINOLOGY

Structure of the intact PPAR-γ–RXR-α nuclear receptor complex on DNA

(2008) Vikas Chandra et al.   NATURE

Structural basis for the activation of PPARγ by oxidized fatty acids

(2008) Toshimasa Itoh et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Molecular recognition of nitrated fatty acids by PPARγ

(2008) Yong Li et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY