Methods for measuring myeloperoxidase activity toward assessing inhibitor efficacy in living systems

Inactivation of myeloperoxidase by benzoic acid hydrazide

(2015) Jiansheng Huang et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Multiscale photoacoustic tomography using reversibly switchable bacterial phytochrome as a near-infrared photochromic probe

(2015) Junjie Yao et al.   NATURE METHODS

Cells make themselves heard

(2015) Srirang Manohar et al.   Nature Photonics

Deep in vivo photoacoustic imaging of mammalian tissues using a tyrosinase-based genetic reporter

(2015) Amit P. Jathoul et al.   Nature Photonics

Multiple Sclerosis: Myeloperoxidase Immunoradiology Improves Detection of Acute and Chronic Disease in Experimental Model

(2015) Benjamin Pulli et al.   RADIOLOGY

Neutrophil extracellular traps license macrophages for cytokine production in atherosclerosis

(2015) A. Warnatsch et al.   SCIENCE

Alkalinity of Neutrophil Phagocytic Vacuoles Is Modulated by HVCN1 and Has Consequences for Myeloperoxidase Activity

(2015) Adam P. Levine et al.   PLoS One

Ordered cleavage of myeloperoxidase ester bonds releases active site heme leading to inactivation of myeloperoxidase by benzoic acid hydrazide analogs

(2014) Jiansheng Huang et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Neutrophils sense microbe size and selectively release neutrophil extracellular traps in response to large pathogens

(2014) Nora Branzk et al.   NATURE IMMUNOLOGY

Semiconducting polymer nanoparticles as photoacoustic molecular imaging probes in living mice

(2014) Kanyi Pu et al.   Nature Nanotechnology

Expression of the secondary granule proteins major basic protein 1 (MBP-1) and eosinophil peroxidase (EPX) is required for eosinophilopoiesis in mice

(2013) A. D. Doyle et al.   BLOOD

Potent Reversible Inhibition of Myeloperoxidase by Aromatic Hydroxamates

(2013) Louisa V. Forbes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Imaging ROS signaling in cells and animals

(2013) Xianhua Wang et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Evaluation of Inflammatory Response to Acute Ischemia Using Near-Infrared Fluorescent Reactive Oxygen Sensors

(2013) Selena Magalotti et al.   MOLECULAR IMAGING AND BIOLOGY

Enhanced detection of myeloperoxidase activity in deep tissues through luminescent excitation of near-infrared nanoparticles

(2013) Ning Zhang et al.   NATURE MEDICINE

Ceruloplasmin: Macromolecular Assemblies with Iron-Containing Acute Phase Proteins

(2013) Valeriya R. Samygina et al.   PLoS One

Measuring Myeloperoxidase Activity in Biological Samples

(2013) Benjamin Pulli et al.   PLoS One

Endogenous Myeloperoxidase Is a Mediator of Joint Inflammation and Damage in Experimental Arthritis

(2013) Dragana Odobasic et al.   Arthritis & Rheumatology

Methods for Detection of Mitochondrial and Cellular Reactive Oxygen Species

(2012) Sergey I. Dikalov et al.   ANTIOXIDANTS & REDOX SIGNALING

The Fluorescein-derived Dye Aminophenyl Fluorescein Is a Suitable Tool to Detect Hypobromous Acid (HOBr)-producing Activity in Eosinophils

(2012) Jörg Flemmig et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reaction-based small-molecule fluorescent probes for chemoselective bioimaging

(2012) Jefferson Chan et al.   Nature Chemistry

Effects of a Novel Pharmacologic Inhibitor of Myeloperoxidase in a Mouse Atherosclerosis Model

(2012) Cuiqing Liu et al.   PLoS One

Myeloperoxidase and oxidative stress in rheumatoid arthritis

(2012) L. K. Stamp et al.   RHEUMATOLOGY

Late Intervention with a Myeloperoxidase Inhibitor Stops Progression of Experimental Chronic Obstructive Pulmonary Disease

(2011) Andrew Churg et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

2-Thioxanthines Are Mechanism-based Inactivators of Myeloperoxidase That Block Oxidative Stress during Inflammation

(2011) Anna-Karin Tidén et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Myeloperoxidase associated with neutrophil extracellular traps is active and mediates bacterial killing in the presence of hydrogen peroxide

(2011) Heather Parker et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Intravital imaging of phagocyte recruitment

(2011) Klaus Kemmerich et al.   THROMBOSIS AND HAEMOSTASIS

Mast cells and inflammation

(2010) Theoharis C. Theoharides et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Molecular Imaging by Means of Multispectral Optoacoustic Tomography (MSOT)

(2010) Vasilis Ntziachristos et al.   CHEMICAL REVIEWS

EPR detection of cellular and mitochondrial superoxide using cyclic hydroxylamines

(2010) Sergey I. Dikalov et al.   FREE RADICAL RESEARCH

Impaired Infarct Healing in Atherosclerotic Mice With Ly-6ChiMonocytosis

(2010) Peter Panizzi et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Going deeper than microscopy: the optical imaging frontier in biology

(2010) Vasilis Ntziachristos   NATURE METHODS

HKGreen-3: A Rhodol-Based Fluorescent Probe for Peroxynitrite

(2010) Tao Peng et al.   ORGANIC LETTERS

Essential Role of Proximal Histidine-Asparagine Interaction in Mammalian Peroxidases

(2009) Xavier Carpena et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Myeloperoxidase Genotypes and Enhanced Efficacy of Chemotherapy for Early-Stage Breast Cancer in SWOG-8897

(2009) Christine B. Ambrosone et al.   JOURNAL OF CLINICAL ONCOLOGY

Oxazine Conjugated Nanoparticle Detects in Vivo Hypochlorous Acid and Peroxynitrite Generation

(2009) Peter Panizzi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Activatable Magnetic Resonance Imaging Agents for Myeloperoxidase Sensing: Mechanism of Activation, Stability, and Toxicity

(2009) Elisenda Rodríguez et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Bioluminescence imaging of myeloperoxidase activity in vivo

(2009) Shimon Gross et al.   NATURE MEDICINE

Multispectral opto-acoustic tomography of deep-seated fluorescent proteins in vivo

(2009) Daniel Razansky et al.   Nature Photonics

Myeloperoxidase-targeted imaging of active inflammatory lesions in murine experimental autoimmune encephalomyelitis

(2008) J. W. Chen et al.   BRAIN

Activatable Magnetic Resonance Imaging Agent Reports Myeloperoxidase Activity in Healing Infarcts and Noninvasively Detects the Antiinflammatory Effects of Atorvastatin on Ischemia-Reperfusion Injury

(2008) Matthias Nahrendorf et al.   CIRCULATION

Myeloperoxidase, modified lipoproteins, and atherogenesis: Fig. 1.

(2008) Stephen J. Nicholls et al.   JOURNAL OF LIPID RESEARCH

A Highly Specific BODIPY-Based Fluorescent Probe for the Detection of Hypochlorous Acid

(2008) Zhen-Ning Sun et al.   ORGANIC LETTERS

Tracking the inflammatory response in stroke in vivo by sensing the enzyme myeloperoxidase

(2008) M. O. Breckwoldt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA