Lessons from a double-transgenic neutrophil approach to induce antiproteinase 3 antibody-mediated vasculitis in mice

Neutrophilic Cathepsin C Is Maturated by a Multistep Proteolytic Process and Secreted by Activated Cells during Inflammatory Lung Diseases

(2016) Yveline Hamon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proteinase 3-ANCA Vasculitis versus Myeloperoxidase-ANCA Vasculitis

(2015) M. Hilhorst et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Neutrophil serine proteases exert proteolytic activity on endothelial cells

(2015) Uwe Jerke et al.   KIDNEY INTERNATIONAL

Proteinase 3–dependent caspase-3 cleavage modulates neutrophil death and inflammation

(2014) Fabien Loison et al.   JOURNAL OF CLINICAL INVESTIGATION

Phagocyte NADPH Oxidase Restrains the Inflammasome in ANCA-Induced GN

(2014) A. Schreiber et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

FcγRIIB regulates T-cell autoreactivity, ANCA production, and neutrophil activation to suppress anti-myeloperoxidase glomerulonephritis

(2014) Joshua D. Ooi et al.   KIDNEY INTERNATIONAL

Antineutrophil cytoplasmic antibody-associated vasculitides: is it time to split up the group?

(2013) Arnaud Millet et al.   ANNALS OF THE RHEUMATIC DISEASES

Relevance of the mouse model as a therapeutic approach for neutrophil proteinase 3-associated human diseases

(2013) Brice Korkmaz et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Ly6 family proteins in neutrophil biology

(2013) Pui Y. Lee et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The Amino-Acid Substituents of Dipeptide Substrates of Cathepsin C Can Determine the Rate-Limiting Steps of Catalysis

(2012) Jon K. Rubach et al.   BIOCHEMISTRY

How anti-neutrophil cytoplasmic autoantibodies activate neutrophils

(2012) R. Kettritz   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Neutrophil Serine Proteases Promote IL-1  Generation and Injury in Necrotizing Crescentic Glomerulonephritis

(2012) A. Schreiber et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Genetically Distinct Subsets within ANCA-Associated Vasculitis

(2012) Paul A. Lyons et al.   NEW ENGLAND JOURNAL OF MEDICINE

Anti-Proteinase 3 Anti-Neutrophil Cytoplasm Autoantibodies Recapitulate Systemic Vasculitis in Mice with a Humanized Immune System

(2012) Mark A. Little et al.   PLoS One

PR3 antibodies do not induce renal pathology in a novel PR3-humanized mouse model for Wegener’s granulomatosis

(2012) Manfred Relle et al.   RHEUMATOLOGY INTERNATIONAL

Myeloperoxidase-Specific Plasma Cell Depletion by Bortezomib Protects from Anti-Neutrophil Cytoplasmic Autoantibodies-Induced Glomerulonephritis

(2011) J. Bontscho et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Elevated Soluble Flt1 Inhibits Endothelial Repair in PR3-ANCA-Associated Vasculitis

(2011) S. Le Roux et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Neutrophil surface presentation of the anti-neutrophil cytoplasmic antibody-antigen proteinase 3 depends on N-terminal processing

(2010) S. Von Vietinghoff et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Anti-PR3 immune responses induce segmental and necrotizing glomerulonephritis

(2010) V. C. Primo et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Complement Receptor Mac-1 Is an Adaptor for NB1 (CD177)-mediated PR3-ANCA Neutrophil Activation

(2010) Uwe Jerke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Coexpression of CD177 and membrane proteinase 3 on neutrophils in antineutrophil cytoplasmic autoantibody-associated systemic vasculitis: Anti-proteinase 3-mediated neutrophil activation is independent of the role of CD177-expressing neutrophils

(2009) N. Hu et al.   ARTHRITIS AND RHEUMATISM

Phosphoinositol 3-kinase-γ mediates antineutrophil cytoplasmic autoantibody-induced glomerulonephritis

(2009) Adrian Schreiber et al.   KIDNEY INTERNATIONAL

Short-Term Heat Exposure Inhibits Inflammation by Abrogating Recruitment of and Nuclear Factor-κB Activation in Neutrophils Exposed to Chemotactic Cytokines

(2008) Mira Choi et al.   AMERICAN JOURNAL OF PATHOLOGY

Neutrophil-selective CD18 silencing using RNA interference in vivo

(2008) X. Cullere et al.   BLOOD

A Hydrophobic Patch on Proteinase 3, the Target of Autoantibodies in Wegener Granulomatosis, Mediates Membrane Binding via NB1 Receptors

(2008) Brice Korkmaz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

C5a Receptor Mediates Neutrophil Activation and ANCA-Induced Glomerulonephritis

(2008) A. Schreiber et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY