Independent origins of fetal liver haematopoietic stem and progenitor cells

Yolk sac, but not hematopoietic stem cell–derived progenitors, sustain erythropoiesis throughout murine embryonic life

(2021) Francisca Soares-da-Silva et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Murine AGM single-cell profiling identifies a continuum of hemogenic endothelium differentiation marked by ACE

(2021) Muhammad Zaki Fadlullah et al.   BLOOD

Integrated analysis of multimodal single-cell data

(2021) Yuhan Hao et al.   CELL

Definitive hematopoietic stem cells minimally contribute to embryonic hematopoiesis

(2021) Bianca A. Ulloa et al.   Cell Reports

Multipotent progenitors and hematopoietic stem cells arise independently from hemogenic endothelium in the mouse embryo

(2021) Tessa Dignum et al.   Cell Reports

An in Situ Atlas of Mitochondrial DNA in Mammalian Tissues Reveals High Content in Stem/Progenitor Cells

(2020) Jiayu Chen et al.   AMERICAN JOURNAL OF PATHOLOGY

Iterative Single-Cell Analyses Define the Transcriptome of the First Functional Hematopoietic Stem Cells

(2020) Chris Sebastiaan Vink et al.   Cell Reports

Hlf marks the developmental pathway for hematopoietic stem cells but not for erythro-myeloid progenitors

(2019) Tomomasa Yokomizo et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Comprehensive Integration of Single-Cell Data

(2019) Tim Stuart et al.   CELL

Single-Cell Profiling Reveals Sex, Lineage, and Regional Diversity in the Mouse Kidney

(2019) Andrew Ransick et al.   DEVELOPMENTAL CELL

Blood Development: Hematopoietic Stem Cell Dependence and Independence

(2018) Elaine Dzierzak et al.   Cell Stem Cell

Causes and Consequences of Hematopoietic Stem Cell Heterogeneity

(2018) Simon Haas et al.   Cell Stem Cell

Integrating single-cell transcriptomic data across different conditions, technologies, and species

(2018) Andrew Butler et al.   NATURE BIOTECHNOLOGY

Single-cell full-length total RNA sequencing uncovers dynamics of recursive splicing and enhancer RNAs

(2018) Tetsutaro Hayashi et al.   Nature Communications

A novel prospective isolation of murine fetal liver progenitors to study in utero hematopoietic defects

(2018) Julia E. Draper et al.   PLoS Genetics

Murine HSCs contribute actively to native hematopoiesis but with reduced differentiation capacity upon aging

(2018) Petter Säwen et al.   eLife

Identification of Stem Cells in the Epithelium of the Stomach Corpus and Antrum of Mice

(2017) Junichi Matsuo et al.   GASTROENTEROLOGY

Haematopoietic stem and progenitor cells from human pluripotent stem cells

(2017) Ryohichi Sugimura et al.   NATURE

In Vivo Generation of Engraftable Murine Hematopoietic Stem Cells by Gfi1b, c-Fos , and Gata2 Overexpression within Teratoma

(2017) Masao Tsukada et al.   Stem Cell Reports

Concealed expansion of immature precursors underpins acute burst of adult HSC activity in foetal liver

(2016) Stanislav Rybtsov et al.   DEVELOPMENT

Hematopoietic Stem Cells Are the Major Source of Multilineage Hematopoiesis in Adult Animals

(2016) Catherine M. Sawai et al.   IMMUNITY

Repopulation dynamics of single haematopoietic stem cells in mouse transplantation experiments: Importance of stem cell composition in competitor cells

(2016) Hideo Ema et al.   JOURNAL OF THEORETICAL BIOLOGY

Tracing haematopoietic stem cell formation at single-cell resolution

(2016) Fan Zhou et al.   NATURE

Protein kinase D regulates positive selection of CD4+ thymocytes through phosphorylation of SHP-1

(2016) Eri Ishikawa et al.   Nature Communications

The Origin of Tissue-Resident Macrophages: When an Erythro-myeloid Progenitor Is an Erythro-myeloid Progenitor

(2015) Elisa Gomez Perdiguero et al.   IMMUNITY

Fundamental properties of unperturbed haematopoiesis from stem cells in vivo

(2015) Katrin Busch et al.   NATURE

Fetal liver hematopoietic stem cell niches associate with portal vessels

(2015) J. A. Khan et al.   SCIENCE

Distinct routes of lineage development reshape the human blood hierarchy across ontogeny

(2015) F. Notta et al.   SCIENCE

Distinct Sources of Hematopoietic Progenitors Emerge before HSCs and Provide Functional Blood Cells in the Mammalian Embryo

(2015) Kathleen E. McGrath et al.   Cell Reports

The role of EVI1 in myeloid malignancies

(2014) Carolyn Glass et al.   BLOOD CELLS MOLECULES AND DISEASES

Neurons Limit Angiogenesis by Titrating VEGF in Retina

(2014) Keisuke Okabe et al.   CELL

Direct induction of haematoendothelial programs in human pluripotent stem cells by transcriptional regulators

(2014) Irina Elcheva et al.   Nature Communications

Clonal Analysis Unveils Self-Renewing Lineage-Restricted Progenitors Generated Directly from Hematopoietic Stem Cells

(2013) Ryo Yamamoto et al.   CELL

Induction of Multipotential Hematopoietic Progenitors from Human Pluripotent Stem Cells via Respecification of Lineage-Restricted Precursors

(2013) Sergei Doulatov et al.   Cell Stem Cell

Transcriptome Analysis Identifies Regulators of Hematopoietic Stem and Progenitor Cells

(2013) Roi Gazit et al.   Stem Cell Reports

Immature hematopoietic stem cells undergo maturation in the fetal liver

(2012) A. Kieusseian et al.   DEVELOPMENT

Whole-mount three-dimensional imaging of internally localized immunostained cells within mouse embryos

(2012) Tomomasa Yokomizo et al.   Nature Protocols

The Human Mitochondrial Transcriptome

(2011) Tim R. Mercer et al.   CELL

Evi1 is essential for hematopoietic stem cell self-renewal, and its expression marks hematopoietic cells with long-term multilineage repopulating activity

(2011) Keisuke Kataoka et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Three-dimensional cartography of hematopoietic clusters in the vasculature of whole mouse embryos

(2010) T. Yokomizo et al.   DEVELOPMENT

In vivo imaging of haematopoietic cells emerging from the mouse aortic endothelium

(2010) Jean-Charles Boisset et al.   NATURE

Runx1 is required for the endothelial to haematopoietic cell transition but not thereafter

(2009) Michael J. Chen et al.   NATURE

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

(2009) Linda Madisen et al.   NATURE NEUROSCIENCE

Hematopoiesis: An Evolving Paradigm for Stem Cell Biology

(2008) Stuart H. Orkin et al.   CELL

Extensive Hematopoietic Stem Cell Generation in the AGM Region via Maturation of VE-Cadherin+CD45+ Pre-Definitive HSCs

(2008) Samir Taoudi et al.   Cell Stem Cell

Evi-1 Is a Critical Regulator for Hematopoietic Stem Cells and Transformed Leukemic Cells

(2008) Susumu Goyama et al.   Cell Stem Cell