Signatures of Convergent Evolution and Natural Selection at the Alcohol Dehydrogenase Gene Region are Correlated with Agriculture in Ethnically Diverse Africans

Hunter-gatherer genomes reveal diverse demographic trajectories during the rise of farming in Eastern Africa

(2022) Shyamalika Gopalan et al.   CURRENT BIOLOGY

Rapid adaptation to malaria facilitated by admixture in the human population of Cabo Verde

(2021) Iman Hamid et al.   eLife

SciPy 1.0: fundamental algorithms for scientific computing in Python

(2020) Pauli Virtanen et al.   NATURE METHODS

The Genomic History of the Bronze Age Southern Levant

(2020) Lily Agranat-Tamir et al.   CELL

Insights into human genetic variation and population history from 929 diverse genomes

(2020) Anders Bergström et al.   SCIENCE

Positive selection in admixed populations from Ethiopia

(2020) Sandra Walsh et al.   BMC GENETICS

Genomic evidence for shared common ancestry of East African hunting-gathering populations and insights into local adaptation

(2019) Laura B. Scheinfeldt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Missing Diversity in Human Genetic Studies

(2019) Giorgio Sirugo et al.   CELL

Functional variants in ADH1B and ALDH2 are non-additively associated with all-cause mortality in Japanese population

(2019) Saori Sakaue et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

West Asian sources of the Eurasian component in Ethiopians: a reassessment

(2019) Ludovica Molinaro et al.   Scientific Reports

Genetic variant repressing ADH1A expression confers susceptibility to esophageal squamous-cell carcinoma

(2018) Qionghua Cui et al.   CANCER LETTERS

The Gateway from Near into Remote Oceania: New Insights from Genome-Wide Data

(2018) Irina Pugach et al.   MOLECULAR BIOLOGY AND EVOLUTION

Patterns of shared signatures of recent positive selection across human populations

(2018) Kelsey Elizabeth Johnson et al.   Nature Ecology & Evolution

Recent Selection on a Class I ADH Locus Distinguishes Southwest Asian Populations Including Ashkenazi Jews

(2018) Sheng Gu et al.   Genes

Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use

(2018) David M. Brazel et al.   BIOLOGICAL PSYCHIATRY

Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112 117)

(2017) T-K Clarke et al.   MOLECULAR PSYCHIATRY

Tracing the peopling of the world through genomics

(2017) Rasmus Nielsen et al.   NATURE

New fossils from Jebel Irhoud, Morocco and the pan-African origin of Homo sapiens

(2017) Jean-Jacques Hublin et al.   NATURE

Dating rice remains through phytolith carbon-14 study reveals domestication at the beginning of the Holocene

(2017) Xinxin Zuo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Loci associated with skin pigmentation identified in African populations

(2017) Nicholas G. Crawford et al.   SCIENCE

Fast Principal-Component Analysis Reveals Convergent Evolution of ADH1B in Europe and East Asia

(2016) Kevin J. Galinsky et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Next-generation genotype imputation service and methods

(2016) Sayantan Das et al.   NATURE GENETICS

Phenome-Wide Association Study for Alcohol and Nicotine Risk Alleles in 26394 Women

(2016) Renato Polimanti et al.   NEUROPSYCHOPHARMACOLOGY

Going global by adapting local: A review of recent human adaptation

(2016) S. Fan et al.   SCIENCE

Common single nucleotide variants underlying drug addiction: more than a decade of research

(2015) Kora-Mareen Bühler et al.   ADDICTION BIOLOGY

Tracing the Route of Modern Humans out of Africa by Using 225 Human Genome Sequences from Ethiopians and Egyptians

(2015) Luca Pagani et al.   AMERICAN JOURNAL OF HUMAN GENETICS

MTTP-297H polymorphism reduced serum cholesterol but increased risk of non-alcoholic fatty liver disease-a cross-sectional study

(2015) Pi-Jung Hsiao et al.   BMC Medical Genetics

A global reference for human genetic variation

(2015) Richard A. Gibbs et al.   NATURE

Evidence for archaic adaptive introgression in humans

(2015) Fernando Racimo et al.   NATURE REVIEWS GENETICS

popart: full-feature software for haplotype network construction

(2015) Jessica W. Leigh et al.   Methods in Ecology and Evolution

Transcriptomic Identification of ADH1B as a Novel Candidate Gene for Obesity and Insulin Resistance in Human Adipose Tissue in Mexican Americans from the Veterans Administration Genetic Epidemiology Study (VAGES)

(2015) Deidre A. Winnier et al.   PLoS One

Single-Nucleotide Polymorphisms Interact to AffectADH7Transcription

(2014) Sowmya Jairam et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Effect of the Allelic Variant of Alcohol DehydrogenaseADH1B*2on Ethanol Metabolism

(2014) Gaeun Kang et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Genetic Origins of Lactase Persistence and the Spread of Pastoralism in Africa

(2014) Alessia Ranciaro et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Functional polymorphism in aldehyde dehydrogenase-2 gene associated with risk of tuberculosis

(2014) Seung Kyu Park et al.   BMC Medical Genetics

Hypobetalipoproteinemia and abetalipoproteinemia

(2014) Francine K. Welty   CURRENT OPINION IN LIPIDOLOGY

Human high-altitude adaptation: forward genetics meets the HIF pathway

(2014) Abigail W. Bigham et al.   GENES & DEVELOPMENT

selscan: An Efficient Multithreaded Program to Perform EHH-Based Scans for Positive Selection

(2014) Z. A. Szpiech et al.   MOLECULAR BIOLOGY AND EVOLUTION

Detecting Recent Positive Selection with High Accuracy and Reliability by Conditional Coalescent Tree

(2014) Minxian Wang et al.   MOLECULAR BIOLOGY AND EVOLUTION

Ancient human genomes suggest three ancestral populations for present-day Europeans

(2014) Iosif Lazaridis et al.   NATURE

Evolutionary dynamics of coding and non-coding transcriptomes

(2014) Anamaria Necsulea et al.   NATURE REVIEWS GENETICS

Ancient west Eurasian ancestry in southern and eastern Africa

(2014) J. K. Pickrell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Early Back-to-Africa Migration into the Horn of Africa

(2014) Jason A. Hodgson et al.   PLoS Genetics

RFMix: A Discriminative Modeling Approach for Rapid and Robust Local-Ancestry Inference

(2013) Brian K. Maples et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Inferring Admixture Histories of Human Populations Using Linkage Disequilibrium

(2013) P.-R. Loh et al.   GENETICS

Recent human adaptation: genomic approaches, interpretation and insights

(2013) Laura B. Scheinfeldt et al.   NATURE REVIEWS GENETICS

Ethiopian Genetic Diversity Reveals Linguistic Stratification and Complex Influences on the Ethiopian Gene Pool

(2012) Luca Pagani et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Distinguishing between Selective Sweeps from Standing Variation and from a De Novo Mutation

(2012) Benjamin M. Peter et al.   PLoS Genetics

Genetic adaptation to high altitude in the Ethiopian highlands

(2012) Laura B Scheinfeldt et al.   GENOME BIOLOGY

Diversification of the ADH1B Gene during Expansion of Modern Humans

(2011) Hui Li et al.   ANNALS OF HUMAN GENETICS

Strong Association of the Alcohol Dehydrogenase 1B Gene (ADH1B) with Alcohol Dependence and Alcohol-Induced Medical Diseases

(2011) Dawei Li et al.   BIOLOGICAL PSYCHIATRY

Regulation of microsomal triglyceride transfer protein

(2011) M Mahmood Hussain et al.   Clinical Lipidology

ADH1B is associated with alcohol dependence and alcohol consumption in populations of European and African ancestry

(2011) L J Bierut et al.   MOLECULAR PSYCHIATRY

A linear complexity phasing method for thousands of genomes

(2011) Olivier Delaneau et al.   NATURE METHODS

A Genome-Wide Association Study of Upper Aerodigestive Tract Cancers Conducted within the INHANCE Consortium

(2011) James D. McKay et al.   PLoS Genetics

The History of African Gene Flow into Southern Europeans, Levantines, and Jews

(2011) Priya Moorjani et al.   PLoS Genetics

Robust relationship inference in genome-wide association studies

(2010) Ani Manichaikul et al.   BIOINFORMATICS

The ADH1B Arg47His polymorphism in East Asian populations and expansion of rice domestication in history

(2010) Yi Peng et al.   BMC EVOLUTIONARY BIOLOGY

Tracking footprints of artificial selection in the dog genome

(2010) J. M. Akey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alcohol and Acetaldehyde in Public Health: From Marvel to Menace

(2010) Rui Guo et al.   International Journal of Environmental Research and Public Health

Fast model-based estimation of ancestry in unrelated individuals

(2009) D. H. Alexander et al.   GENOME RESEARCH

Variability in ethanol biodisposition in whites is modulated by polymorphisms in theADH1BandADH1Cgenes

(2009) Carmen Martínez et al.   HEPATOLOGY

ADH single nucleotide polymorphism associations with alcohol metabolism in vivo

(2009) Andrew J. Birley et al.   HUMAN MOLECULAR GENETICS

The Genetic Structure and History of Africans and African Americans

(2009) S. A. Tishkoff et al.   SCIENCE

Multiple ADH genes are associated with upper aerodigestive cancers

(2008) Mia Hashibe et al.   NATURE GENETICS