Design of Hybrid MnO2-Polymer-Lipid Nanoparticles with Tunable Oxygen Generation Rates and Tumor Accumulation for Cancer Treatment

Nanoparticle–blood interactions: the implications on solid tumour targeting

(2015) James Lazarovits et al.   CHEMICAL COMMUNICATIONS

A Multifunctional Polymeric Nanotheranostic System Delivers Doxorubicin and Imaging Agents across the Blood–Brain Barrier Targeting Brain Metastases of Breast Cancer

(2014) Jason Li et al.   ACS Nano

Multifunctional Albumin–MnO2 Nanoparticles Modulate Solid Tumor Microenvironment by Attenuating Hypoxia, Acidosis, Vascular Endothelial Growth Factor and Enhance Radiation Response

(2014) Preethy Prasad et al.   ACS Nano

Synergistic Nanoparticulate Drug Combination Overcomes Multidrug Resistance, Increases Efficacy, and Reduces Cardiotoxicity in a Nonimmunocompromised Breast Tumor Model

(2014) Adam J. Shuhendler et al.   MOLECULAR PHARMACEUTICS

Evaluation of Azathioprine-Induced Cytotoxicity in anIn VitroRat Hepatocyte System

(2014) Abdullah Al Maruf et al.   Biomed Research International

ZnO nanoparticle-induced oxidative stress triggers apoptosis by activating JNK signaling pathway in cultured primary astrocytes

(2014) Jieting Wang et al.   Nanoscale Research Letters

25th Anniversary Article: Metal Oxide Particles in Materials Science: Addressing All Length Scales

(2013) Dorota Koziej et al.   ADVANCED MATERIALS

Toxicity assessment of manganese oxide micro and nanoparticles in Wistar rats after 28 days of repeated oral exposure

(2013) Shailendra Pratap Singh et al.   JOURNAL OF APPLIED TOXICOLOGY

Hypoxia-inducing factors as master regulators of stemness properties and altered metabolism of cancer- and metastasis-initiating cells

(2013) Murielle Mimeault et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Multifunctional terpolymeric MRI contrast agent with superior signal enhancement in blood and tumor

(2013) Alireza Shalviri et al.   JOURNAL OF CONTROLLED RELEASE

Matrigel alters the pathophysiology of orthotopic human breast adenocarcinoma xenografts with implications for nanomedicine evaluation

(2013) Adam J. Shuhendler et al.   Nanomedicine-Nanotechnology Biology and Medicine

Investigating Mechanisms of Alkalinization for Reducing Primary Breast Tumor Invasion

(2013) Ian F. Robey et al.   Biomed Research International

Hybrid Nanoparticles for Detection and Treatment of Cancer

(2012) Michael J. Sailor et al.   ADVANCED MATERIALS

The impact of tumor microenvironment on cancer treatment and its modulation by direct and indirect antivascular strategies

(2012) Emmanouil Fokas et al.   CANCER AND METASTASIS REVIEWS

Doxorubicin and mitomycin C co-loaded polymer-lipid hybrid nanoparticles inhibit growth of sensitive and multidrug resistant human mammary tumor xenografts

(2012) Preethy Prasad et al.   CANCER LETTERS

Tumor Hypoxia Predicts Biochemical Failure following Radiotherapy for Clinically Localized Prostate Cancer

(2012) M. Milosevic et al.   CLINICAL CANCER RESEARCH

Design of pH-responsive nanoparticles of terpolymer of poly(methacrylic acid), polysorbate 80 and starch for delivery of doxorubicin

(2012) Alireza Shalviri et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

pH-Dependent doxorubicin release from terpolymer of starch, polymethacrylic acid and polysorbate 80 nanoparticles for overcoming multi-drug resistance in human breast cancer cells

(2012) Alireza Shalviri et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Overcoming evasive resistance from vascular endothelial growth factor a inhibition in sarcomas by genetic or pharmacologic targeting of hypoxia-inducible factor 1α

(2012) Yeo-Jung Kim et al.   INTERNATIONAL JOURNAL OF CANCER

Resistance and Escape From Antiangiogenesis Therapy: Clinical Implications and Future Strategies

(2012) Justin N. Bottsford-Miller et al.   JOURNAL OF CLINICAL ONCOLOGY

Safety assessment of nanomaterials: Implications for nanomedicine

(2012) Andreas M. Nyström et al.   JOURNAL OF CONTROLLED RELEASE

The microenvironment and resistance to personalized cancer therapy

(2012) Shigeo Masuda et al.   Nature Reviews Clinical Oncology

Overcoming disappointing results with antiangiogenic therapy by targeting hypoxia

(2012) Annamaria Rapisarda et al.   Nature Reviews Clinical Oncology

Radiation-Induced Vascular Damage in Tumors: Implications of Vascular Damage in Ablative Hypofractionated Radiotherapy (SBRT and SRS)

(2012) Heon Joo Park et al.   RADIATION RESEARCH

A Novel Solid Lipid Nanoparticle Formulation for Active Targeting to Tumor αvβ3Integrin Receptors Reveals Cyclic RGD as A Double-Edged Sword

(2012) Adam J. Shuhendler et al.   Advanced Healthcare Materials

Drug Resistance and Cellular Adaptation to Tumor Acidic pH Microenvironment

(2011) Jonathan W. Wojtkowiak et al.   MOLECULAR PHARMACEUTICS

Toxicology and clinical potential of nanoparticles

(2011) Lara Yildirimer et al.   Nano Today

Nanotechnology-Enabled Closed Loop Insulin Delivery Device: In Vitro and In Vivo Evaluation of Glucose-Regulated Insulin Release for Diabetes Control

(2010) Claudia R. Gordijo et al.   ADVANCED FUNCTIONAL MATERIALS

Glucose-Responsive Bioinorganic Nanohybrid Membrane for Self-Regulated Insulin Release

(2010) Claudia R. Gordijo et al.   ADVANCED FUNCTIONAL MATERIALS

Beyond Intercalation-Based Li-Ion Batteries: The State of the Art and Challenges of Electrode Materials Reacting Through Conversion Reactions

(2010) Jordi Cabana et al.   ADVANCED MATERIALS

Modulating the tumor microenvironment to increase radiation responsiveness

(2010) Jayashree Karar et al.   CANCER BIOLOGY & THERAPY

Manganese oxide-based materials as electrochemical supercapacitor electrodes

(2010) Weifeng Wei et al.   CHEMICAL SOCIETY REVIEWS

Factors that Control the Circulation Time of Nanoparticles in Blood: Challenges, Solutions and Future Prospects

(2010) Jin-Wook Yoo et al.   CURRENT PHARMACEUTICAL DESIGN

Drug delivery and nanoparticles: Applications and hazards

(2010) de Jong   International Journal of Nanomedicine

Nanosponge formulations as oxygen delivery systems

(2010) Roberta Cavalli et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Tumour hypoxia induces a metabolic shift causing acidosis: a common feature in cancer

(2010) Johanna Chiche et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Mechanism for α-MnO2 Nanowire-Induced Cytotoxicity in Hela Cells

(2010) Yan Li et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Nano Titanium Dioxide Induces the Generation of ROS and Potential Damage in HaCaT Cells Under UVA Irradiation

(2010) Chengbin Xue et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Stimulus-responsive macromolecules and nanoparticles for cancer drug delivery

(2010) Sarah R MacEwan et al.   Nanomedicine

Strategies in the design of nanoparticles for therapeutic applications

(2010) Robby A. Petros et al.   NATURE REVIEWS DRUG DISCOVERY

Hemoglobin-based Oxygen Carriers Combined with Anticancer Drugs May Enhance Sensitivity of Radiotherapy and Chemotherapy to Solid Tumors

(2009) Wei Wu et al.   ARTIFICIAL CELLS BLOOD SUBSTITUTES AND IMMOBILIZATION BIOTECHNOLOGY

Increasing Sensitivity to Radiotherapy and Chemotherapy by Using Novel Biological Agents that Alter the Tumor Microenvironment

(2009) E. Shinohara et al.   CURRENT MOLECULAR MEDICINE

Hypoxia and Radiation Therapy: Past History, Ongoing Research, and Future Promise

(2009) Sara Rockwell et al.   CURRENT MOLECULAR MEDICINE

The evidence for solid lipid nanoparticles mediated cell uptake of resveratrol

(2009) K. Teskač et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

NK-Dependent Increases in CCL22 Secretion Selectively Recruits Regulatory T Cells to the Tumor Microenvironment

(2009) A. W. Mailloux et al.   JOURNAL OF IMMUNOLOGY

Multifunctional nanoparticles – properties and prospects for their use in human medicine

(2008) Nuria Sanvicens et al.   TRENDS IN BIOTECHNOLOGY

Cellular uptake of solid lipid nanoparticles and cytotoxicity of encapsulated paclitaxel in A549 cancer cells

(2007) H YUAN et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS