Factor XIa inhibition with asundexian after acute non-cardioembolic ischaemic stroke (PACIFIC-Stroke): an international, randomised, double-blind, placebo-controlled, phase 2b trial
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Title
Factor XIa inhibition with asundexian after acute non-cardioembolic ischaemic stroke (PACIFIC-Stroke): an international, randomised, double-blind, placebo-controlled, phase 2b trial
Authors
Keywords
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Journal
LANCET
Volume 400, Issue 10357, Pages 997-1007
Publisher
Elsevier BV
Online
2022-09-03
DOI
10.1016/s0140-6736(22)01588-4
References
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Note: Only part of the references are listed.- Safety of the oral factor XIa inhibitor asundexian compared with apixaban in patients with atrial fibrillation (PACIFIC-AF): a multicentre, randomised, double-blind, double-dummy, dose-finding phase 2 study
- (2022) Jonathan P Piccini et al. LANCET
- Factor XI as a Target for New Anticoagulants
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- Canadian Stroke Best Practice Recommendations: Secondary Prevention of Stroke Update 2020
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- Factor XI Inhibition to Uncouple Thrombosis From Hemostasis
- (2021) Charles Hsu et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Associations of coagulation factor X and XI with incident acute coronary syndrome and stroke: A nested case‐control study
- (2021) Huiting Chen et al. JOURNAL OF THROMBOSIS AND HAEMOSTASIS
- Abelacimab for Prevention of Venous Thromboembolism
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- Frequency and Patterns of Brain Infarction in Patients With Embolic Stroke of Undetermined Source: NAVIGATE ESUS Trial
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- 2021 Guideline for the Prevention of Stroke in Patients With Stroke and Transient Ischemic Attack: A Guideline From the American Heart Association/American Stroke Association
- (2021) Dawn O. Kleindorfer et al. STROKE
- Milvexian for the Prevention of Venous Thromboembolism
- (2021) Jeffrey I. Weitz et al. NEW ENGLAND JOURNAL OF MEDICINE
- Effect of Osocimab in Preventing Venous Thromboembolism Among Patients Undergoing Knee Arthroplasty
- (2020) Jeffrey I. Weitz et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Ticagrelor and Aspirin or Aspirin Alone in Acute Ischemic Stroke or TIA
- (2020) S. Claiborne Johnston et al. NEW ENGLAND JOURNAL OF MEDICINE
- Rivaroxaban for Prevention of Covert Brain Infarcts and Cognitive Decline
- (2020) Mukul Sharma et al. STROKE
- Novel Drug Targets for Ischemic Stroke Identified Through Mendelian Randomization Analysis of the Blood Proteome
- (2019) Michael Chong et al. CIRCULATION
- Association Between Low-Dose Rivaroxaban With or Without Aspirin and Ischemic Stroke Subtypes
- (2019) Kanjana S. Perera et al. JAMA Neurology
- Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA
- (2018) S. Claiborne Johnston et al. NEW ENGLAND JOURNAL OF MEDICINE
- Genetically Determined FXI (Factor XI) Levels and Risk of Stroke
- (2018) Dipender Gill et al. STROKE
- Rivaroxaban with or without Aspirin in Stable Cardiovascular Disease
- (2017) John W. Eikelboom et al. NEW ENGLAND JOURNAL OF MEDICINE
- Factor XI Deficiency Protects Against Atherogenesis in Apolipoprotein E/Factor XI Double Knockout MiceSignificance
- (2016) Reut Shnerb Ganor et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Factor XI Antisense Oligonucleotide for Prevention of Venous Thrombosis
- (2015) Harry R. Büller et al. NEW ENGLAND JOURNAL OF MEDICINE
- The Heidelberg Bleeding Classification
- (2015) Rüdiger von Kummer et al. STROKE
- Antigen levels of coagulation factor XII, coagulation factor XI and prekallikrein, and the risk of myocardial infarction and ischemic stroke in young women
- (2014) B. Siegerink et al. JOURNAL OF THROMBOSIS AND HAEMOSTASIS
- Clopidogrel with Aspirin in Acute Minor Stroke or Transient Ischemic Attack
- (2013) Yongjun Wang et al. NEW ENGLAND JOURNAL OF MEDICINE
- Reduced incidence of ischemic stroke in patients with severe factor XI deficiency
- (2008) O. Salomon et al. BLOOD
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