An S-glutathiomimetic provides structural insights into stromal interaction molecule-1 regulation

Defects in the STIM1 SOARα2 domain affect multiple steps in the CRAC channel activation cascade

(2021) Carmen Höglinger et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Synergistic stabilization by nitrosoglutathione-induced thiol modifications in the stromal interaction molecule-2 luminal domain suppresses basal and store operated calcium entry

(2020) Matthew J. Novello et al.   Scientific Reports

Crosstalk between N-terminal and C-terminal domains in stromal interaction molecule 2 (STIM2) determines enhanced STIM2 sensitivity

(2019) Scott M. Emrich et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CRAC Channels And Disease – From Human CRAC Channelopathies And Animal Models To Novel Drugs

(2019) Stefan Feske   CELL CALCIUM

Sequential activation of STIM1 links Ca2+ with luminal domain unfolding

(2019) Romana Schober et al.   Science Signaling

A charge-sensing region in the stromal interaction molecule 1 luminal domain confers stabilization-mediated inhibition of SOCE in response toS-nitrosylation

(2018) Jinhui Zhu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

S -Nitrosylation of STIM1 by Neuronal Nitric Oxide Synthase Inhibits Store-Operated Ca 2+ Entry

(2018) Le Gui et al.   JOURNAL OF MOLECULAR BIOLOGY

Protein Glutathionylation in the Pathogenesis of Neurodegenerative Diseases

(2017) Sun Joo Cha et al.   Oxidative Medicine and Cellular Longevity

Clustal Omega for making accurate alignments of many protein sequences

(2017) Fabian Sievers et al.   PROTEIN SCIENCE

Quantitative biology of hydrogen peroxide signaling

(2017) Fernando Antunes et al.   Redox Biology

S-Glutathionylation Enhances Human Cystathionine β-Synthase Activity Under Oxidative Stress Conditions

(2015) Wei-Ning Niu et al.   ANTIOXIDANTS & REDOX SIGNALING

A Coiled-coil Clamp Controls Both Conformation and Clustering of Stromal Interaction Molecule 1 (STIM1)

(2014) Marc Fahrner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protein glutathionylation in health and disease

(2013) Pietro Ghezzi   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

STIM1/Orai1 coiled-coil interplay in the regulation of store-operated calcium entry

(2013) Peter B. Stathopulos et al.   Nature Communications

S-Glutathionylation: From Molecular Mechanisms to Health Outcomes

(2011) Ying Xiong et al.   ANTIOXIDANTS & REDOX SIGNALING

STIM1 couples to ORAI1 via an intramolecular transition into an extended conformation

(2011) Martin Muik et al.   EMBO JOURNAL

Modulation of STIM1 and capacitative Ca2+ entry by the endoplasmic reticulum luminal oxidoreductase ERp57

(2011) Daniel Prins et al.   EMBO REPORTS

Reversible and irreversible protein glutathionylation: biological and clinical aspects

(2011) Arthur JL Cooper et al.   Expert Opinion on Drug Metabolism & Toxicology

Stimulated association of STIM1 and Orai1 is regulated by the balance of PtdIns(4,5)P2 between distinct membrane pools

(2011) N. Calloway et al.   JOURNAL OF CELL SCIENCE

Effect of protein S-glutathionylation on Ca2+ homeostasis in cultured aortic endothelial cells

(2010) Jeffrey T. Lock et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

S-glutathionylation activates STIM1 and alters mitochondrial homeostasis

(2010) Brian J. Hawkins et al.   JOURNAL OF CELL BIOLOGY

Role of phosphoinositides in STIM1 dynamics and store-operated calcium entry

(2009) Ciara M. Walsh et al.   BIOCHEMICAL JOURNAL

STIM1 Clusters and Activates CRAC Channels via Direct Binding of a Cytosolic Domain to Orai1

(2009) Chan Young Park et al.   CELL

Dependence of STIM1/Orai1-mediated Calcium Entry on Plasma Membrane Phosphoinositides

(2009) Marek K. Korzeniowski et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Short N-terminal Domains of STIM1 and STIM2 Control the Activation Kinetics of Orai1 Channels

(2009) Yandong Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SOAR and the polybasic STIM1 domains gate and regulate Orai channels

(2009) Joseph P. Yuan et al.   NATURE CELL BIOLOGY

Assessment of Endoplasmic Reticulum Glutathione Redox Status Is Confounded by Extensive Ex Vivo Oxidation

(2008) Brian M. Dixon et al.   ANTIOXIDANTS & REDOX SIGNALING

Structural and Mechanistic Insights into STIM1-Mediated Initiation of Store-Operated Calcium Entry

(2008) Peter B. Stathopulos et al.   CELL

Regulation of glutathione synthesis

(2008) Shelly C. Lu   MOLECULAR ASPECTS OF MEDICINE

Oligomerization of STIM1 couples ER calcium depletion to CRAC channel activation

(2008) Riina M. Luik et al.   NATURE