Activation of cGAS‐STING pathway – A possible cause of myofiber atrophy/necrosis in dermatomyositis and immune‐mediated necrotizing myopathy

Self-DNA Sensing by cGAS-STING and TLR9 in Autoimmunity: Is the Cytoskeleton in Control?

(2021) Roberto Amadio et al.   Frontiers in Immunology

Mitochondrial DNA leakage induces odontoblast inflammation via the cGAS-STING pathway

(2021) Lu Zhou et al.   Cell Communication and Signaling

The Clinicopathological Distinction Between Seropositive and Seronegative Immune-Mediated Necrotizing Myopathy in China

(2021) Xue Ma et al.   Frontiers in Neurology

It Takes Two to Tango: The Role of Dysregulated Metabolism and Inflammation in Kidney Disease Development

(2020) Ghazal Z. Quinn et al.   SEMINARS IN NEPHROLOGY

TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS

(2020) Chien-Hsiung Yu et al.   CELL

Crosstalk between cGAS–STING signaling and cell death

(2020) Ambika M. V. Murthy et al.   CELL DEATH AND DIFFERENTIATION

The cGAS‐STING pathway: The role of self‐DNA sensing in inflammatory lung disease

(2020) Ruihua Ma et al.   FASEB JOURNAL

The kiss of (cell) death: can venom-induced immune response contribute to dermal necrosis following arthropod envenomations?

(2019) John P. Dunbar et al.   CLINICAL TOXICOLOGY

Identification of distinctive interferon gene signatures in different types of myositis

(2019) Iago Pinal-Fernandez et al.   NEUROLOGY

Mitochondrial Damage and Activation of the STING Pathway Lead to Renal Inflammation and Fibrosis

(2019) Ki Wung Chung et al.   Cell Metabolism

Mitochondrial Damage Causes Inflammation via cGAS-STING Signaling in Acute Kidney Injury

(2019) Hiroshi Maekawa et al.   Cell Reports

JAK inhibitor improves type I interferon induced damage: proof of concept in dermatomyositis

(2018) Leandro Ladislau et al.   BRAIN

JAK-STAT signaling pathway inhibition: a role for treatment of discoid lupus erythematosus and dermatomyositis

(2018) Jared S. Kahn et al.   INTERNATIONAL JOURNAL OF DERMATOLOGY

Activation of the STING-IRF3 pathway promotes hepatocyte inflammation, apoptosis and induces metabolic disorders in nonalcoholic fatty liver disease

(2018) J.T. Qiao et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

224th ENMC International Workshop:

(2018) Yves Allenbach et al.   NEUROMUSCULAR DISORDERS

TNFα and Radioresistant Stromal Cells Are Essential for Therapeutic Efficacy of Cyclic Dinucleotide STING Agonists in Nonimmunogenic Tumors

(2018) Brian J. Francica et al.   Cancer Immunology Research

Classification and management of adult inflammatory myopathies

(2018) Albert Selva-O'Callaghan et al.   LANCET NEUROLOGY

Diagnostic potential of sarcoplasmic MxA expression in subsets of dermatomyositis

(2018) Akinori Uruha et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

STING directly activates autophagy to tune the innate immune response

(2018) Dong Liu et al.   CELL DEATH AND DIFFERENTIATION

STING Signaling Promotes Apoptosis, Necrosis, and Cell Death: An Overview and Update

(2018) Song Liu et al.   MEDIATORS OF INFLAMMATION

DsbA-L prevents obesity-induced inflammation and insulin resistance by suppressing the mtDNA release-activated cGAS-cGAMP-STING pathway

(2017) Juli Bai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hypoxia triggers IFN-I production in muscle: Implications in dermatomyositis

(2017) Noemí De Luna et al.   Scientific Reports

Autoantibody Specificities and Type I Interferon Pathway Activation in Idiopathic Inflammatory Myopathies

(2016) L. Ekholm et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

cGAS Senses Human Cytomegalovirus and Induces Type I Interferon Responses in Human Monocyte-Derived Cells

(2016) Jennifer Paijo et al.   PLoS Pathogens

Interferons as components of the complex web of reactions sustaining inflammation in idiopathic inflammatory myopathies

(2015) Boel De Paepe   CYTOKINE

The role of type I interferons and other cytokines in dermatomyositis

(2015) Ashish Arshanapalli et al.   CYTOKINE

Role of Toll-like receptors and retinoic acid inducible gene I in endogenous production of type I interferon in dermatomyositis

(2015) Ling Li et al.   JOURNAL OF NEUROIMMUNOLOGY

Altered RIG-I/DDX58-mediated innate immunity in dermatomyositis

(2014) Xavier Suárez-Calvet et al.   JOURNAL OF PATHOLOGY

Translocation of mixed lineage kinase domain-like protein to plasma membrane leads to necrotic cell death

(2013) Xin Chen et al.   CELL RESEARCH

Immune-Mediated Necrotizing Myopathy Is Characterized by a Specific Th1-M1 Polarized Immune Profile

(2012) Corinna Preuße et al.   AMERICAN JOURNAL OF PATHOLOGY

Interferon and Biologic Signatures in Dermatomyositis Skin: Specificity and Heterogeneity across Diseases

(2012) David Wong et al.   PLoS One

Cell death in HeLa mediated by thermoplastic polyurethane with co-immobilized IFN-γ plus TNF-α

(2011) Yan-Qing Guan et al.   Acta Biomaterialia

Relationship between disease activity and type 1 interferon- and other cytokine-inducible gene expression in blood in dermatomyositis and polymyositis

(2011) S A Greenberg et al.   GENES AND IMMUNITY

Interferon-stimulated gene 15 (ISG15) conjugates proteins in dermatomyositis muscle with perifascicular atrophy

(2009) Mohammad Salajegheh et al.   ANNALS OF NEUROLOGY