Prediction and evaluation of combination pharmacotherapy using natural language processing, machine learning and patient electronic health records

Drug repurposing for opioid use disorders: integration of computational prediction, clinical corroboration, and mechanism of action analyses

(2021) Mengshi Zhou et al.   MOLECULAR PSYCHIATRY

DrugComb update: a more comprehensive drug sensitivity data repository and analysis portal

(2021) Shuyu Zheng et al.   NUCLEIC ACIDS RESEARCH

The global epidemiology of hypertension

(2020) Katherine T. Mills et al.   Nature Reviews Nephrology

DTF: Deep Tensor Factorization for Predicting Anticancer Drug Synergy

(2020) Zexuan Sun et al.   BIOINFORMATICS

Leveraging multi-way interactions for systematic prediction of pre-clinical drug combination effects

(2020) Heli Julkunen et al.   Nature Communications

Treatment Combinations for Alzheimer’s Disease: Current And Future Pharmacotherapy Options

(2019) Jeffrey L. Cummings et al.   JOURNAL OF ALZHEIMERS DISEASE

Network-based prediction of drug combinations

(2019) Feixiong Cheng et al.   Nature Communications

Immunotherapy and targeted therapy combinations in metastatic breast cancer

(2019) Francisco J Esteva et al.   LANCET ONCOLOGY

DrugComb: an integrative cancer drug combination data portal

(2019) Bulat Zagidullin et al.   NUCLEIC ACIDS RESEARCH

Epidemiology and treatment of pulmonary arterial hypertension

(2017) Edmund M. T. Lau et al.   Nature Reviews Cardiology

DrugBank 5.0: a major update to the DrugBank database for 2018

(2017) David S Wishart et al.   NUCLEIC ACIDS RESEARCH

Mechanism-Independent Optimization of Combinatorial Nanodiamond and Unmodified Drug Delivery Using a Phenotypically Driven Platform Technology

(2015) Hann Wang et al.   ACS Nano

STITCH 5: augmenting protein–chemical interaction networks with tissue and affinity data

(2015) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Searching for Drug Synergy in Complex Dose–Response Landscapes Using an Interaction Potency Model

(2015) Bhagwan Yadav et al.   Computational and Structural Biotechnology Journal

dRiskKB: a large-scale disease-disease risk relationship knowledge base constructed from biomedical text

(2014) Rong Xu et al.   BMC BIOINFORMATICS

ASDCD: Antifungal Synergistic Drug Combination Database

(2014) Xing Chen et al.   PLoS One

Towards building a disease-phenotype knowledge base: extracting disease-manifestation relationship from literature

(2013) R. Xu et al.   BIOINFORMATICS

Parallel comparison of Illumina RNA-Seq and Affymetrix microarray platforms on transcriptomic profiles generated from 5-aza-deoxy-cytidine treated HT-29 colon cancer cells and simulated datasets

(2013) Xiao Xu et al.   BMC BIOINFORMATICS

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Angiotensin II receptor blocker combinations: From guidelines to clinical practice

(2011) Krzysztof Narkiewicz   BLOOD PRESSURE

Intratubular Renin-Angiotensin System in Hypertension

(2011) L. Gabriel Navar et al.   HYPERTENSION

Scalable tensor factorizations for incomplete data

(2010) Evrim Acar et al.   CHEMOMETRICS AND INTELLIGENT LABORATORY SYSTEMS

Synergistic drug combinations tend to improve therapeutically relevant selectivity

(2009) Joseph Lehár et al.   NATURE BIOTECHNOLOGY

Tensor Decompositions and Applications

(2009) Tamara G. Kolda et al.   SIAM REVIEW