MicroRNAs Constitute a Negative Feedback Loop inStreptococcus pneumoniae–Induced Macrophage Activation

Cylindromatosis (CYLD) inhibits Streptococcus pneumonia -induced plasminogen activator inhibitor-1 expression via interacting with TRAF-6

(2015) Jing Wu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Resistance patterns and outcomes in intensive care unit (ICU)-acquired pneumonia. Validation of European Centre for Disease Prevention and Control (ECDC) and the Centers for Disease Control and Prevention (CDC) classification of multidrug resistant organisms

(2015) Ignacio Martin-Loeches et al.   JOURNAL OF INFECTION

Community-acquired pneumonia as medical emergency: predictors of early deterioration

(2015) Martin Kolditz et al.   THORAX

Genome-wide association study of survival from sepsis due to pneumonia: an observational cohort study

(2015) Anna Rautanen et al.   Lancet Respiratory Medicine

Serotype 1 and 8 Pneumococci Evade Sensing by Inflammasomes in Human Lung Tissue

(2015) Diana Fatykhova et al.   PLoS One

MicroRNA-155 Is Required for Clearance of Streptococcus pneumoniae from the Nasopharynx

(2014) Chris P. Verschoor et al.   INFECTION AND IMMUNITY

Morphine Induces Defects in Early Response of Alveolar Macrophages to Streptococcus pneumoniae by Modulating TLR9-NF- B Signaling

(2014) J. Wang et al.   JOURNAL OF IMMUNOLOGY

Mycobacterium tuberculosisDecreases Human Macrophage IFN-γ Responsiveness through miR-132 and miR-26a

(2014) Bin Ni et al.   JOURNAL OF IMMUNOLOGY

Streptococcus pneumoniae–Induced Oxidative Stress in Lung Epithelial Cells Depends on Pneumococcal Autolysis and Is Reversible by Resveratrol

(2014) Janine Zahlten et al.   JOURNAL OF INFECTIOUS DISEASES

miR-155 Suppresses Bacterial Clearance in Pseudomonas aeruginosa–Induced Keratitis by Targeting Rheb

(2014) Kun Yang et al.   JOURNAL OF INFECTIOUS DISEASES

miRNA-146 negatively regulates the production of pro-inflammatory cytokines via NF-κB signalling in human gingival fibroblasts

(2014) Yu-feng Xie et al.   Journal of Inflammation-London

Differential Expression of microRNAs in Francisella tularensis-Infected Human Macrophages: miR-155-Dependent Downregulation of MyD88 Inhibits the Inflammatory Response

(2014) Sarmistha Bandyopadhyay et al.   PLoS One

Severe Sepsis and Septic Shock

(2013) Derek C. Angus et al.   NEW ENGLAND JOURNAL OF MEDICINE

BDNF/TrkB Signaling Augments Smooth Muscle Cell Proliferation in Pulmonary Hypertension

(2012) Grazyna Kwapiszewska et al.   AMERICAN JOURNAL OF PATHOLOGY

Streptococcus pneumoniae-induced regulation of cyclooxygenase-2 in human lung tissue

(2012) Kolja V. Szymanski et al.   EUROPEAN RESPIRATORY JOURNAL

TLR9- and Src-dependent expression of Krueppel-like factor 4 controls interleukin-10 expression in pneumonia

(2012) Janine Zahlten et al.   EUROPEAN RESPIRATORY JOURNAL

Identifying Functional MicroRNAs in Macrophages with Polarized Phenotypes

(2012) Joel W. Graff et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA-146a negatively regulates PTGS2 expression induced by Helicobacter pylori in human gastric epithelial cells

(2012) Zhen Liu et al.   JOURNAL OF GASTROENTEROLOGY

Earliest Innate Immune Responses Require Macrophage RelA during Pneumococcal Pneumonia

(2011) Lynnelle A. Pittet et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

The Acute Respiratory Distress Syndrome: Pathogenesis and Treatment

(2011) Michael A. Matthay et al.   Annual Review of Pathology-Mechanisms of Disease

Interleukin-1β Regulates CXCL8 Release and Influences Disease Outcome in Response to Streptococcus pneumoniae, Defining Intercellular Cooperation between Pulmonary Epithelial Cells and Macrophages

(2011) Helen M. Marriott et al.   INFECTION AND IMMUNITY

Morphine Inhibits Murine Dendritic Cell IL-23 Production by Modulating Toll-like Receptor 2 and Nod2 Signaling

(2011) Jinghua Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Critical Roles of ASC Inflammasomes in Caspase-1 Activation and Host Innate Resistance to Streptococcus pneumoniae Infection

(2011) R. Fang et al.   JOURNAL OF IMMUNOLOGY

Streptococcus pneumoniae DNA Initiates Type I Interferon Signaling in the Respiratory Tract

(2011) D. Parker et al.   mBio

Interferon-γ Production by Neutrophils during Bacterial Pneumonia in Mice

(2010) Mitsuhiro Yamada et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Pattern Recognition Receptors and Inflammation

(2010) Osamu Takeuchi et al.   CELL

Association of Serotype with Risk of Death Due to Pneumococcal Pneumonia: A Meta‐Analysis

(2010) Daniel M. Weinberger et al.   CLINICAL INFECTIOUS DISEASES

TLR2- and Nucleotide-Binding Oligomerization Domain 2-Dependent Kruppel-Like Factor 2 Expression Downregulates NF- B-Related Gene Expression

(2010) J. Zahlten et al.   JOURNAL OF IMMUNOLOGY

MicroRNA-124 promotes microglia quiescence and suppresses EAE by deactivating macrophages via the C/EBP-α–PU.1 pathway

(2010) Eugene D Ponomarev et al.   NATURE MEDICINE

Pneumolysin Activates the NLRP3 Inflammasome and Promotes Proinflammatory Cytokines Independently of TLR4

(2010) Edel A. McNeela et al.   PLoS Pathogens

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Myeloid RelA regulates pulmonary host defense networks

(2009) C. Hess et al.   EUROPEAN RESPIRATORY JOURNAL

Comparative gene expression profiling of post-natal and post-pneumonectomy lung growth

(2009) J-C. Wolff et al.   EUROPEAN RESPIRATORY JOURNAL

Burden of disease caused by Streptococcus pneumoniae in children younger than 5 years: global estimates

(2009) Katherine L O'Brien et al.   LANCET

Induction of microRNAs, mir-155, mir-222, mir-424 and mir-503, promotes monocytic differentiation through combinatorial regulation

(2009) A R R Forrest et al.   LEUKEMIA

miR-147, a microRNA that is induced upon Toll-like receptor stimulation, regulates murine macrophage inflammatory responses

(2009) G. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modulation of the Inflammatory Response toStreptococcus pneumoniaein a Model of Acute Lung Tissue Infection

(2008) Feng Xu et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Incidence, Etiology, Timing, and Risk Factors for Clinical Failure in Hospitalized Patients With Community-Acquired Pneumonia

(2008) Stefano Aliberti et al.   CHEST

Contribution of IL-1 to resistance to Streptococcus pneumoniae infection

(2008) D. Kafka et al.   INTERNATIONAL IMMUNOLOGY

Trends in antibacterial resistance among Streptococcus pneumoniae isolated in the USA: update from PROTEKT US Years 1–4

(2008) Stephen G Jenkins et al.   Annals of Clinical Microbiology and Antimicrobials