Shp2 Deficiency Impairs the Inflammatory Response AgainstHaemophilus influenzaeby Regulating Macrophage Polarization

Eosinophil differentiation in the bone marrow is promoted by protein tyrosine phosphatase SHP2

(2016) L-x Xia et al.   Cell Death & Disease

SH2 Domain-Containing Protein Tyrosine Phosphatase 2 and Focal Adhesion Kinase Protein Interactions Regulate Pulmonary Endothelium Barrier Function

(2015) Havovi Chichger et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Calcium Restores the Macrophage Response to NontypeableHaemophilus influenzaein Chronic Obstructive Pulmonary Disease

(2015) Karin A. Provost et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Shp-2 contributes to anti-RSV activity in human pulmonary alveolar epithelial cells by interfering with the IFN-α-induced Jak/Stat1 pathway

(2015) Saisai Wang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Inhibition of SHP2-mediated dephosphorylation of Ras suppresses oncogenesis

(2015) Severa Bunda et al.   Nature Communications

Macrophage heterogeneity in tissues: phenotypic diversity and functions

(2014) Siamon Gordon et al.   IMMUNOLOGICAL REVIEWS

SHP2 Positively Regulates TGFβ1-induced Epithelial-Mesenchymal Transition Modulated by Its Novel Interacting Protein Hook1

(2014) Shuomin Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Macrophage Polarization in Bacterial Infections

(2014) M. Benoit et al.   JOURNAL OF IMMUNOLOGY

Myeloid-Specific Disruption of Tyrosine Phosphatase Shp2 Promotes Alternative Activation of Macrophages and Predisposes Mice to Pulmonary Fibrosis

(2014) Bo Tao et al.   JOURNAL OF IMMUNOLOGY

MiR-127 Modulates Macrophage Polarization and Promotes Lung Inflammation and Injury by Activating the JNK Pathway

(2014) Hangjie Ying et al.   JOURNAL OF IMMUNOLOGY

Impaired innate immune alveolar macrophage response and the predilection for COPD exacerbations

(2014) Charles S Berenson et al.   THORAX

Akt1-Mediated Regulation of Macrophage Polarization in a Murine Model of Staphylococcus aureus Pulmonary Infection

(2013) Feng Xu et al.   JOURNAL OF INFECTIOUS DISEASES

Phagocytic Dysfunction of Human Alveolar Macrophages and Severity of Chronic Obstructive Pulmonary Disease

(2013) Charles S. Berenson et al.   JOURNAL OF INFECTIOUS DISEASES

Loss of Shp2 in alveoli epithelia induces deregulated surfactant homeostasis, resulting in spontaneous pulmonary fibrosis

(2012) Xue Zhang et al.   FASEB JOURNAL

Shp2 Plays an Important Role in Acute Cigarette Smoke-Mediated Lung Inflammation

(2012) F.-f. Li et al.   JOURNAL OF IMMUNOLOGY

NR4A1 (Nur77) Deletion Polarizes Macrophages Toward an Inflammatory Phenotype and Increases Atherosclerosis

(2011) Richard N. Hanna et al.   CIRCULATION RESEARCH

Potentiation ofHelicobacter pyloriCagA Protein Virulence through Homodimerization

(2011) Lisa Nagase et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Krüppel-like factor 4 regulates macrophage polarization

(2011) Xudong Liao et al.   JOURNAL OF CLINICAL INVESTIGATION

Protein Tyrosine Phosphatase SHP-2 Is Positively Involved in Platelet-Derived Growth Factor–Signaling in Vascular Neointima Formation via the Reactive Oxygen Species–Related Pathway

(2011) Kyung-Jong Won et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Activation of Epidermal Growth Factor Receptor Is Required for NTHi-Induced NF-κB-Dependent Inflammation

(2011) Xiangbin Xu et al.   PLoS One

Targeting Nrf2 Signaling Improves Bacterial Clearance by Alveolar Macrophages in Patients with COPD and in a Mouse Model

(2011) C. J. Harvey et al.   Science Translational Medicine

Alternative Activation of Macrophages: Mechanism and Functions

(2010) Siamon Gordon et al.   IMMUNITY

CC Chemokine Ligand 3 Overcomes the Bacteriocidal and Phagocytic Defect of Macrophages and Hastens Recovery from Experimental Otitis Media in TNF-/- Mice

(2010) A. Leichtle et al.   JOURNAL OF IMMUNOLOGY

Vinpocetine inhibits NF- B-dependent inflammation via an IKK-dependent but PDE-independent mechanism

(2010) K.-I. Jeon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protein tyrosine phosphatases in glioma biology

(2009) Anna C. Navis et al.   ACTA NEUROPATHOLOGICA

Role of protein tyrosine phosphatase SHP2 in barrier function of pulmonary endothelium

(2009) K. L. Grinnell et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Tolerance and M2 (alternative) macrophage polarization are related processes orchestrated by p50 nuclear factor  B

(2009) C. Porta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Myeloid Differentiation Primary Response Gene 88 Is Required for the Resolution of Otitis Media

(2008) Michelle Hernandez et al.   JOURNAL OF INFECTIOUS DISEASES

Infection in the Pathogenesis and Course of Chronic Obstructive Pulmonary Disease

(2008) Sanjay Sethi et al.   NEW ENGLAND JOURNAL OF MEDICINE