TLR-Activated Gap Junction Channels Protect Mice against Bacterial Infection through Extracellular UDP Release

DAMPs as mediators of sterile inflammation in aging-related pathologies

(2015) Noa Feldman et al.   AGEING RESEARCH REVIEWS

Extracellular ATP induces the rapid release of HIV-1 from virus containing compartments of human macrophages

(2015) Francesca Graziano et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ATP-Gated Ionotropic P2X7 Receptor Controls Follicular T Helper Cell Numbers in Peyer’s Patches to Promote Host-Microbiota Mutualism

(2014) Michele Proietti et al.   IMMUNITY

Atractylenolide I inhibits lipopolysaccharide-induced inflammatory responses via mitogen-activated protein kinase pathways in RAW264.7 cells

(2014) Guangquan Ji et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Toll-Like Receptor-Triggered Calcium Mobilization Protects Mice against Bacterial Infection through Extracellular ATP Release

(2014) Hua Ren et al.   INFECTION AND IMMUNITY

Extracellular UDP and P2Y6Function as a Danger Signal To Protect Mice from Vesicular Stomatitis Virus Infection through an Increase in IFN-β Production

(2014) Ruimei Li et al.   JOURNAL OF IMMUNOLOGY

Sessile alveolar macrophages communicate with alveolar epithelium to modulate immunity

(2014) Kristin Westphalen et al.   NATURE

Nucleotide signalling during inflammation

(2014) Marco Idzko et al.   NATURE

P2Y6 Receptor Potentiates Pro-Inflammatory Responses in Macrophages and Exhibits Differential Roles in Atherosclerotic Lesion Development

(2014) Ricardo A. Garcia et al.   PLoS One

Pulmonary Infection with Hypervirulent Mycobacteria Reveals a Crucial Role for the P2X7 Receptor in Aggressive Forms of Tuberculosis

(2014) Eduardo P. Amaral et al.   PLoS Pathogens

RAGE and TLRs: Relatives, friends or neighbours?

(2013) Zaridatul Aini Ibrahim et al.   MOLECULAR IMMUNOLOGY

Autocrine Regulation of Macrophage Activation via Exocytosis of ATP and Activation of P2Y11 Receptor

(2013) Hayato Sakaki et al.   PLoS One

Activation of neuronal P2X7 receptor–pannexin-1 mediates death of enteric neurons during colitis

(2012) Brian D Gulbransen et al.   NATURE MEDICINE

The P2X7 receptor–pannexin-1 complex decreases muscarinic acetylcholine receptor–mediated seizure susceptibility in mice

(2011) Ji-Eun Kim et al.   JOURNAL OF CLINICAL INVESTIGATION

Uridine 5'-Diphosphate Induces Chemokine Expression in Microglia and Astrocytes through Activation of the P2Y6 Receptor

(2011) B. Kim et al.   JOURNAL OF IMMUNOLOGY

P2Y6 Agonist Uridine 5'-Diphosphate Promotes Host Defense against Bacterial Infection via Monocyte Chemoattractant Protein-1-Mediated Monocytes/Macrophages Recruitment

(2011) Z. Zhang et al.   JOURNAL OF IMMUNOLOGY

Pannexin-1 hemichannel-mediated ATP release together with P2X1 and P2X4 receptors regulate T-cell activation at the immune synapse

(2010) T. Woehrle et al.   BLOOD

Pannexin 1 channels mediate ‘find-me’ signal release and membrane permeability during apoptosis

(2010) Faraaz B. Chekeni et al.   NATURE

Concomitant activation of P2Y2and P2Y6receptors on monocytes is required for TLR1/2-induced neutrophil migration by regulating IL-8 secretion

(2009) Fethia Ben Yebdri et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance

(2009) Michael R. Elliott et al.   NATURE

Modulation of Brain Hemichannels and Gap Junction Channels by Pro-Inflammatory Agents and Their Possible Role in Neurodegeneration

(2008) Juan A. Orellana et al.   ANTIOXIDANTS & REDOX SIGNALING

An efficient culture method for generating large quantities of mature mouse splenic macrophages

(2008) Attiya Alatery et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Sequential control of Toll-like receptor–dependent responses by IRAK1 and IRAK2

(2008) Tatsukata Kawagoe et al.   NATURE IMMUNOLOGY

Purinergic Control of T Cell Activation by ATP Released Through Pannexin-1 Hemichannels

(2008) U. Schenk et al.   Science Signaling