Lipid nanoparticle-encapsulated VEGFa siRNA facilitates cartilage formation by suppressing angiogenesis

Exosomes derived from hypoxia preconditioned mesenchymal stem cells laden in a silk hydrogel promote cartilage regeneration via the miR-205-5p/PTEN/AKT pathway

(2022) Kai Shen et al.   Acta Biomaterialia

Hydrogel composite scaffolds achieve recruitment and chondrogenesis in cartilage tissue engineering applications

(2022) Bo Huang et al.   JOURNAL OF NANOBIOTECHNOLOGY

Evaluation of CD49f as a novel surface marker to identify functional adipose‐derived mesenchymal stem cell subset

(2021) Kangkang Zha et al.   CELL PROLIFERATION

The role of HIF proteins in maintaining the metabolic health of the intervertebral disc

(2021) Elizabeth S. Silagi et al.   Nature Reviews Rheumatology

Lactate Consumption via Cascaded Enzymes Combined VEGF siRNA for Synergistic Anti‐Proliferation and Anti‐Angiogenesis Therapy of Tumors

(2021) Yan Tang et al.   Advanced Healthcare Materials

Hypoxia Inducible Factor-1α Is a Regulator of Autophagy in Osteoarthritic Chondrocytes

(2021) Junren Lu et al.   Cartilage

Difference in the lipid nanoparticle technology employed in three approved siRNA (Patisiran) and mRNA (COVID-19 vaccine) drugs

(2021) Yuta Suzuki et al.   Drug Metabolism and Pharmacokinetics

Hypoxia-Conditioned Mesenchymal Stem Cells in Tissue Regeneration Application

(2021) Yanmeng Yang et al.   Tissue Engineering Part B-Reviews

Hypoxia induces DOT1L in articular cartilage to protect against osteoarthritis

(2021) Astrid De Roover et al.   JCI Insight

Lipid availability determines fate of skeletal progenitor cells via SOX9

(2020) Nick van Gastel et al.   NATURE

Recent advances in siRNA delivery mediated by lipid-based nanoparticles

(2020) Sei Yonezawa et al.   ADVANCED DRUG DELIVERY REVIEWS

Cyclopropenium Nanoparticles and Gene Transfection in Cells

(2020) Noam Y. Steinman et al.   Pharmaceutics

Experimental approach to nasal septal cartilage regeneration with adipose tissue‐derived stem cells and decellularized porcine septal cartilage

(2020) Constanze Kuhlmann et al.   XENOTRANSPLANTATION

3D bioprinting of a biomimetic meniscal scaffold for application in tissue engineering

(2020) Zhou Jian et al.   Bioactive Materials

Hypoxia impacts human MSC response to substrate stiffness during chondrogenic differentiation

(2019) Daniel A. Foyt et al.   Acta Biomaterialia

Hypoxia mimicking hydrogels to regulate the fate of transplanted stem cells

(2019) Binulal N. Sathy et al.   Acta Biomaterialia

Strategies, design, and chemistry in siRNA delivery systems

(2019) Yizhou Dong et al.   ADVANCED DRUG DELIVERY REVIEWS

siRNA therapeutics: a clinical reality

(2019) Phei Er Saw et al.   Science China-Life Sciences

Intensified Stiffness and Photodynamic Provocation in a Collagen‐Based Composite Hydrogel Drive Chondrogenesis

(2019) Li Zheng et al.   Advanced Science

Implications of Angiogenesis Involvement in Arthritis

(2018) Iona MacDonald et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Overview on natural hydrophilic polysaccharide polymers in drug delivery

(2018) Fatemeh Abedini et al.   POLYMERS FOR ADVANCED TECHNOLOGIES

Design of synthetic materials for intracellular delivery of RNAs: From siRNA-mediated gene silencing to CRISPR/Cas gene editing

(2018) Jason B. Miller et al.   Nano Research

Chasing Chimeras – The elusive stable chondrogenic phenotype

(2018) Valeria Graceffa et al.   BIOMATERIALS

Effect of the nanoformulation of siRNA-lipid assemblies on their cellular uptake and immune stimulation

(2017) Kohei Kubota et al.   International Journal of Nanomedicine

Prospects of siRNA applications in regenerative medicine

(2017) Fatemeh Mottaghitalab et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Advances in the delivery of RNA therapeutics: from concept to clinical reality

(2017) James C. Kaczmarek et al.   Genome Medicine

Interaction of HIF1α and β-catenin inhibits matrix metalloproteinase 13 expression and prevents cartilage damage in mice

(2016) Wafa Bouaziz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mesenchymal stem cells and immunomodulation: current status and future prospects

(2016) F Gao et al.   Cell Death & Disease

Spontaneous In Vivo Chondrogenesis of Bone Marrow-Derived Mesenchymal Progenitor Cells by Blocking Vascular Endothelial Growth Factor Signaling

(2016) Anna Marsano et al.   Stem Cells Translational Medicine

Synthesis, properties, and biomedical applications of gelatin methacryloyl (GelMA) hydrogels

(2015) Kan Yue et al.   BIOMATERIALS

Silk fibroin nanoparticle as a novel drug delivery system

(2015) Fatemeh Mottaghitalab et al.   JOURNAL OF CONTROLLED RELEASE

Cartilage Regeneration in the Head and Neck Area

(2015) Mieke M. Pleumeekers et al.   PLASTIC AND RECONSTRUCTIVE SURGERY

Modulated release from liposomes entrapped in chitosan/gelatin hydrogels

(2014) Bogdan C. Ciobanu et al.   Materials Science & Engineering C-Materials for Biological Applications

The effect of hypoxia on the chondrogenic differentiation of co-cultured articular chondrocytes and mesenchymal stem cells in scaffolds

(2013) Ville V. Meretoja et al.   BIOMATERIALS

Chondrogenesis of adipose stem cells in a porous PLGA scaffold impregnated with plasmid DNA containing SOX trio (SOX-5,-6 and -9) genes

(2011) Gun-Il Im et al.   BIOMATERIALS

Target specific tumor treatment by VEGF siRNA complexed with reducible polyethyleneimine–hyaluronic acid conjugate

(2010) Kitae Park et al.   BIOMATERIALS

A SiRNA Targeting Vascular Endothelial Growth Factor-A Inhibiting Experimental Corneal Neovascularization

(2010) Lei Zuo et al.   CURRENT EYE RESEARCH

Microfluidic Synthesis of Nanomaterials

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