PX478-loaded silk fibroin nanoparticles reverse multidrug resistance by inhibiting the hypoxia-inducible factor

Oral nanotherapeutics based on Antheraea pernyi silk fibroin for synergistic treatment of ulcerative colitis

(2022) Ya Ma et al.   BIOMATERIALS

Carbon nano-onion-mediated dual targeting of P-selectin and P-glycoprotein to overcome cancer drug resistance

(2021) Hai Wang et al.   Nature Communications

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2021) Hyuna Sung et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Therapeutic strategies to overcome taxane resistance in cancer

(2021) Tuyelee Das et al.   DRUG RESISTANCE UPDATES

Folic acid-functionalized tea polyphenol as a tumor-targeting nano-drug delivery system

(2021) Di Chuan et al.   MATERIALS & DESIGN

Phenylboronic Acid Modification Augments the Lysosome Escape and Antitumor Efficacy of a Cylindrical Polymer Brush-Based Prodrug

(2021) Ruonan Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Improvement of conventional anti-cancer drugs as new tools against multidrug resistant tumors

(2020) Sabrina Dallavalle et al.   DRUG RESISTANCE UPDATES

Tumor microenvironment-activatable Fe-doxorubicin preloaded amorphous CaCO3 nanoformulation triggers ferroptosis in target tumor cells

(2020) Chen-Cheng Xue et al.   Science Advances

Surface modified silk fibroin nanoparticles for improved delivery of doxorubicin: Development, characterization, in-vitro studies

(2020) Vikas Pandey et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Folic acid functionalized starch encapsulated green synthesized copper oxide nanoparticles for targeted drug delivery in breast cancer therapy

(2020) Mariadoss Arokia Vijaya Anand et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

HIF Inhibitors: Status of Current Clinical Development

(2019) Jaleh Fallah et al.   Current Oncology Reports

Multi-bioresponsive silk fibroin-based nanoparticles with on-demand cytoplasmic drug release capacity for CD44-targeted alleviation of ulcerative colitis

(2019) Shuangquan Gou et al.   BIOMATERIALS

Tyrosine kinase inhibitors enhanced the efficacy of conventional chemotherapeutic agent in multidrug resistant cancer cells

(2018) Shaocong Wu et al.   Molecular Cancer

Hierarchically stimuli-responsive nanovectors for improved tumor penetration and programed tumor therapy

(2018) Junjie Liu et al.   Nanoscale

Nonviral gene editing via CRISPR/Cas9 delivery by membrane-disruptive and endosomolytic helical polypeptide

(2018) Hong-Xia Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tumor Oxygenation and Hypoxia Inducible Factor-1 Functional Inhibition via a Reactive Oxygen Species Responsive Nanoplatform for Enhancing Radiation Therapy and Abscopal Effects

(2018) Lingtong Meng et al.   ACS Nano

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Therapeutic targeting of hypoxia and hypoxia-inducible factors in cancer

(2016) Caroline Wigerup et al.   PHARMACOLOGY & THERAPEUTICS

Target Specific Delivery of Anticancer Drug in Silk Fibroin Based 3D Distribution Model of Bone–Breast Cancer Cells

(2015) Bano Subia et al.   ACS Applied Materials & Interfaces

Targeting the folate receptor: diagnostic and therapeutic approaches to personalize cancer treatments

(2015) J. A. Ledermann et al.   ANNALS OF ONCOLOGY

Reactive oxygen species and glutathione dual redox-responsive micelles for selective cytotoxicity of cancer

(2015) Yi-Ting Chiang et al.   BIOMATERIALS

Silk Fibroin-Based Nanoparticles for Drug Delivery

(2015) Zheng Zhao et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Development, Maintenance, and Reversal of Multiple Drug Resistance: At the Crossroads of TFPI1, ABC Transporters, and HIF1

(2015) Terra Arnason et al.   Cancers

A pH-sensitive gene delivery system based on folic acid-PEG-chitosan – PAMAM-plasmid DNA complexes for cancer cell targeting

(2013) Mingyue Wang et al.   BIOMATERIALS

Reactive and Bioactive Cationic α-Helical Polypeptide Template for Nonviral Gene Delivery

(2011) Nathan P. Gabrielson et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A novel approach to cancer therapy using PX-478 as a HIF-1α inhibitor

(2011) Kyeong Lee et al.   ARCHIVES OF PHARMACAL RESEARCH

Ionic polypeptides with unusual helical stability

(2011) Hua Lu et al.   Nature Communications

Biomaterials from Ultrasonication-Induced Silk Fibroin−Hyaluronic Acid Hydrogels

(2010) Xiao Hu et al.   BIOMACROMOLECULES

ABC Efflux Pump-Based Resistance to Chemotherapy Drugs

(2009) Paul D. W. Eckford et al.   CHEMICAL REVIEWS

Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding

(2009) S. G. Aller et al.   SCIENCE