Class-Switch Recombination in the Absence of the IgH 3′ Regulatory Region

Sequential activation and distinct functions for distal and proximal modules within the IgH 3′ regulatory region

(2016) Armand Garot et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Redundant function of DNA ligase 1 and 3 in alternative end-joining during immunoglobulin class switch recombination

(2016) Shahnaz Masani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deciphering the importance of the palindromic architecture of the immunoglobulin heavy-chain 3’ regulatory region

(2016) Alexis Saintamand et al.   Nature Communications

The SAGA Deubiquitination Module Promotes DNA Repair and Class Switch Recombination through ATM and DNAPK-Mediated γH2AX Formation

(2016) Shaliny Ramachandran et al.   Cell Reports

Non-coding RNA Generated following Lariat Debranching Mediates Targeting of AID to DNA

(2015) Simin Zheng et al.   CELL

AID targeting: old mysteries and new challenges

(2015) Vivek Chandra et al.   TRENDS IN IMMUNOLOGY

Spt5 accumulation at variable genes distinguishes somatic hypermutation in germinal center B cells from ex vivo–activated cells

(2014) Robert W. Maul et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Targeting Of Somatic Hypermutation By immunoglobulin Enhancer And Enhancer-Like Sequences

(2014) Jean-Marie Buerstedde et al.   PLOS BIOLOGY

The IgH 3′ regulatory region controls somatic hypermutation in germinal center B cells

(2013) Pauline Rouaud et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Alternative End-Joining and Classical Nonhomologous End-Joining Pathways Repair Different Types of Double-Strand Breaks during Class-Switch Recombination

(2013) E. M. Cortizas et al.   JOURNAL OF IMMUNOLOGY

RNA-Guided Human Genome Engineering via Cas9

(2013) P. Mali et al.   SCIENCE

AID-Driven Deletion Causes Immunoglobulin Heavy Chain Locus Suicide Recombination in B Cells

(2012) S. Peron et al.   SCIENCE

Enhancement of Antibody Class-Switch Recombination by the Cumulative Activity of Four Separate Elements

(2011) W. A. Dunnick et al.   JOURNAL OF IMMUNOLOGY

Overlapping activation-induced cytidine deaminase hotspot motifs in Ig class-switch recombination

(2011) L. Han et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genomic deletion of the whole IgH 3' regulatory region (hs3a, hs1,2, hs3b, and hs4) dramatically affects class switch recombination and Ig secretion to all isotypes

(2010) C. Vincent-Fabert et al.   BLOOD

Attracting AID to targets of somatic hypermutation

(2010) Atsushi Tanaka et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Switch recombination and somatic hypermutation are controlled by the heavy chain 3′ enhancer region

(2009) Wesley A. Dunnick et al.   JOURNAL OF EXPERIMENTAL MEDICINE