Gut Microbiota Regulates K/BxN Autoimmune Arthritis through Follicular Helper T but Not Th17 Cells

Of Mice and Men: Defining the Role of Interleukin 17 in Rheumatoid Arthritis

(2015) E. M. RUDERMAN   JOURNAL OF RHEUMATOLOGY

A Study to Evaluate the Safety, Tolerability, and Efficacy of Brodalumab in Subjects with Rheumatoid Arthritis and an Inadequate Response to Methotrexate

(2015) K. Pavelka et al.   JOURNAL OF RHEUMATOLOGY

The IL-23–IL-17 axis in inflammatory arthritis

(2015) Erik Lubberts   Nature Reviews Rheumatology

Follicular helper T cell-mediated mucosal barrier maintenance

(2014) Colleen J. Winstead   IMMUNOLOGY LETTERS

IL-17A Inhibits the Expansion of IL-17A-Producing T Cells in Mice through "Short-Loop" Inhibition via IL-17 Receptor

(2014) E. Smith et al.   JOURNAL OF IMMUNOLOGY

Development of Proteoglycan-Induced Arthritis Is Independent of IL-17

(2014) P. D. Doodes et al.   JOURNAL OF IMMUNOLOGY

One-year Efficacy and Safety Results of Secukinumab in Patients With Rheumatoid Arthritis: Phase II, Dose-finding, Double-blind, Randomized, Placebo-controlled Study

(2014) M. C. Genovese et al.   JOURNAL OF RHEUMATOLOGY

Endoscopic photoconversion reveals unexpectedly broad leukocyte trafficking to and from the gut

(2014) A. M. Morton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Phase II Randomized Study of Subcutaneous Ixekizumab, an Anti-Interleukin-17 Monoclonal Antibody, in Rheumatoid Arthritis Patients Who Were Naive to Biologic Agents or Had an Inadequate Response to Tumor Necrosis Factor Inhibitors

(2014) Mark C. Genovese et al.   Arthritis & Rheumatology

Gut-residing Microbes Alter the Host Susceptibility to Autoantibody-mediated Arthritis

(2014) Hyerim Lee et al.   Immune Network

SOCS3 Transactivation by PPAR  Prevents IL-17-Driven Cancer Growth

(2013) H. Berger et al.   CANCER RESEARCH

The Cellular Source and Target of IL-21 in K/BxN Autoimmune Arthritis

(2013) K. E. Block et al.   JOURNAL OF IMMUNOLOGY

Insights into the Role of Bcl6 in Follicular Th Cells Using a New Conditional Mutant Mouse Model

(2013) K. Hollister et al.   JOURNAL OF IMMUNOLOGY

IL-17RA Is Essential for Optimal Localization of Follicular Th Cells in the Germinal Center Light Zone To Promote Autoantibody-Producing B Cells

(2013) Y. Ding et al.   JOURNAL OF IMMUNOLOGY

Neutrophils Are Essential As A Source Of Il-17 In The Effector Phase Of Arthritis

(2013) Masaki Katayama et al.   PLoS One

IL-17 cytokines in immunity and inflammation

(2013) Wei Jin et al.   Emerging Microbes & Infections

Th17 cell-derived IL-17 is dispensable for B cell antibody production

(2012) Akiko Shibui et al.   CYTOKINE

Prostaglandin E2 Suppresses Antifungal Immunity by Inhibiting Interferon Regulatory Factor 4 Function and Interleukin-17 Expression in T Cells

(2012) Patricia A. Valdez et al.   IMMUNITY

Priming of Natural Killer Cells by Nonmucosal Mononuclear Phagocytes Requires Instructive Signals from Commensal Microbiota

(2012) Stephanie C. Ganal et al.   IMMUNITY

Lymphotoxin regulates commensal responses to enable diet-induced obesity

(2012) Vaibhav Upadhyay et al.   NATURE IMMUNOLOGY

Follicular Helper CD4 T Cells (TFH)

(2011) Shane Crotty   Annual Review of Immunology

The role of Th17 lymphocytes in the autoimmune and chronic inflammatory diseases

(2011) Giuseppe Murdaca et al.   Internal and Emergency Medicine

Fate mapping of IL-17-producing T cells in inflammatory responses

(2011) Keiji Hirota et al.   NATURE IMMUNOLOGY

IL-17RA Signaling Amplifies Antibody-Induced Arthritis

(2011) Christian D. Sadik et al.   PLoS One

Characterization of the KRN Cell Transfer Model of Rheumatoid Arthritis (KRN-CTM), a Chronic Yet Synchronized Version of the K/BxN Mouse

(2010) Timothy P. LaBranche et al.   AMERICAN JOURNAL OF PATHOLOGY

Gut-Residing Segmented Filamentous Bacteria Drive Autoimmune Arthritis via T Helper 17 Cells

(2010) Hsin-Jung Wu et al.   IMMUNITY

Recognition of peptidoglycan from the microbiota by Nod1 enhances systemic innate immunity

(2010) Thomas B Clarke et al.   NATURE MEDICINE

Proinflammatory T helper type 17 cells are effective B-cell helpers

(2010) M. Mitsdoerffer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria

(2009) Ivaylo I. Ivanov et al.   CELL

The Key Role of Segmented Filamentous Bacteria in the Coordinated Maturation of Gut Helper T Cell Responses

(2009) Valérie Gaboriau-Routhiau et al.   IMMUNITY

Th17 cells in autoimmune disease: changing the verdict

(2009) Stefan Haak et al.   Immunotherapy

IL-17A and IL-17F do not contribute vitally to autoimmune neuro-inflammation in mice

(2008) Stefan Haak et al.   JOURNAL OF CLINICAL INVESTIGATION