IL-17 cytokines in immunity and inflammation

The Human IL-17F/IL-17A Heterodimeric Cytokine Signals through the IL-17RA/IL-17RC Receptor Complex

(2014) J. F. Wright et al.   JOURNAL OF IMMUNOLOGY

IL-17A Produced by    T Cells Plays a Critical Role in Innate Immunity against Listeria monocytogenes Infection in the Liver

(2014) S. Hamada et al.   JOURNAL OF IMMUNOLOGY

Transcription of Il17 and Il17f Is Controlled by Conserved Noncoding Sequence 2

(2012) Xiaohu Wang et al.   IMMUNITY

Negative regulation of IL-17-mediated signaling and inflammation by the ubiquitin-specific protease USP25

(2012) Bo Zhong et al.   NATURE IMMUNOLOGY

Induction and molecular signature of pathogenic TH17 cells

(2012) Youjin Lee et al.   NATURE IMMUNOLOGY

Genetic controls of Th17 cell differentiation and plasticity

(2011) Chen Dong   EXPERIMENTAL AND MOLECULAR MEDICINE

Interleukin-17C Promotes Th17 Cell Responses and Autoimmune Disease via Interleukin-17 Receptor E

(2011) Seon Hee Chang et al.   IMMUNITY

Functional Specialization of Interleukin-17 Family Members

(2011) Yoichiro Iwakura et al.   IMMUNITY

IL-17RE is the functional receptor for IL-17C and mediates mucosal immunity to infection with intestinal pathogens

(2011) Xinyang Song et al.   NATURE IMMUNOLOGY

Fate mapping of IL-17-producing T cells in inflammatory responses

(2011) Keiji Hirota et al.   NATURE IMMUNOLOGY

IL-17C regulates the innate immune function of epithelial cells in an autocrine manner

(2011) Vladimir Ramirez-Carrozzi et al.   NATURE IMMUNOLOGY

The inducible kinase IKKi is required for IL-17-dependent signaling associated with neutrophilia and pulmonary inflammation

(2011) Katarzyna Bulek et al.   NATURE IMMUNOLOGY

Identification of an innate T helper type 17 response to intestinal bacterial pathogens

(2011) Kaoru Geddes et al.   NATURE MEDICINE

LY2439821, a humanized anti-interleukin-17 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: A phase I randomized, double-blind, placebo-controlled, proof-of-concept study

(2010) M. C. Genovese et al.   ARTHRITIS AND RHEUMATISM

Signaling of interleukin-17 family cytokines in immunity and inflammation

(2010) Seon Hee Chang et al.   CELLULAR SIGNALLING

IL-17 family member cytokines: Regulation and function in innate immunity

(2010) Joseph M. Reynolds et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Toll-like Receptor 2 Signaling in CD4+ T Lymphocytes Promotes T Helper 17 Responses and Regulates the Pathogenesis of Autoimmune Disease

(2010) Joseph M. Reynolds et al.   IMMUNITY

Dectin-2 Recognition of α-Mannans and Induction of Th17 Cell Differentiation Is Essential for Host Defense against Candida albicans

(2010) Shinobu Saijo et al.   IMMUNITY

IL-17 is essential for host defense against cutaneous Staphylococcus aureus infection in mice

(2010) John S. Cho et al.   JOURNAL OF CLINICAL INVESTIGATION

Effects of AIN457, a Fully Human Antibody to Interleukin-17A, on Psoriasis, Rheumatoid Arthritis, and Uveitis

(2010) W. Hueber et al.   Science Translational Medicine

Differential Roles of Interleukin-17A and -17F in Host Defense against Mucoepithelial Bacterial Infection and Allergic Responses

(2009) Harumichi Ishigame et al.   IMMUNITY

Interleukin-17-Producing γδ T Cells Selectively Expand in Response to Pathogen Products and Environmental Signals

(2009) Bruno Martin et al.   IMMUNITY

IL-23 Is Required for Protection against Systemic Infection with Listeria monocytogenes

(2009) K. D. Meeks et al.   JOURNAL OF IMMUNOLOGY

Regulation of inflammatory responses by IL-17F

(2008) Xuexian O. Yang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Impaired TH17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome

(2008) Joshua D. Milner et al.   NATURE

Simian immunodeficiency virus–induced mucosal interleukin-17 deficiency promotes Salmonella dissemination from the gut

(2008) Manuela Raffatellu et al.   NATURE MEDICINE

IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia

(2008) Shean J Aujla et al.   NATURE MEDICINE