ERβ in CD4+T Cells Is Crucial for Ligand-Mediated Suppression of Central Nervous System Autoimmunity

Th17 cells transdifferentiate into regulatory T cells during resolution of inflammation

(2015) Nicola Gagliani et al.   NATURE

Loss of estrogen-mediated immunoprotection underlies female gender bias in experimental Crohn’s-like ileitis

(2014) W A Goodman et al.   Mucosal Immunology

Osteopontin expression by CD103−dendritic cells drives intestinal inflammation

(2014) Evangelia Kourepini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multiple functional therapeutic effects of the estrogen receptor β agonist indazole-Cl in a mouse model of multiple sclerosis

(2014) Spencer M. Moore et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Coexpression of CD49b and LAG-3 identifies human and mouse T regulatory type 1 cells

(2013) Nicola Gagliani et al.   NATURE MEDICINE

Estrogen receptor β ligand therapy activates PI3K/Akt/mTOR signaling in oligodendrocytes and promotes remyelination in a mouse model of multiple sclerosis

(2013) Shalini Kumar et al.   NEUROBIOLOGY OF DISEASE

Targeting estrogen receptor β in microglia and T cells to treat experimental autoimmune encephalomyelitis

(2013) Wan-fu Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Estrogen treatment prevents gray matter atrophy in experimental autoimmune encephalomyelitis

(2012) Allan J. MacKenzie-Graham et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Induction and molecular signature of pathogenic TH17 cells

(2012) Youjin Lee et al.   NATURE IMMUNOLOGY

An ADIOL-ERβ-CtBP Transrepression Pathway Negatively Regulates Microglia-Mediated Inflammation

(2011) Kaoru Saijo et al.   CELL

Notch Signaling Regulates Mouse and Human Th17 Differentiation

(2011) S. Keerthivasan et al.   JOURNAL OF IMMUNOLOGY

The role of estrogen receptor β (ERβ) in malignant diseases—A new potential target for antiproliferative drugs in prevention and treatment of cancer

(2010) Margaret Warner et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Generation of pathogenic TH17 cells in the absence of TGF-β signalling

(2010) Kamran Ghoreschi et al.   NATURE

The aryl hydrocarbon receptor interacts with c-Maf to promote the differentiation of type 1 regulatory T cells induced by IL-27

(2010) Lionel Apetoh et al.   NATURE IMMUNOLOGY

Activation of the aryl hydrocarbon receptor induces human type 1 regulatory T cell–like and Foxp3+ regulatory T cells

(2010) Roopali Gandhi et al.   NATURE IMMUNOLOGY

T helper type 1 and 17 cells determine efficacy of interferon-β in multiple sclerosis and experimental encephalomyelitis

(2010) Robert C Axtell et al.   NATURE MEDICINE

The nuclear receptor PPARγ selectively inhibits Th17 differentiation in a T cell–intrinsic fashion and suppresses CNS autoimmunity

(2009) Luisa Klotz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Additive effects of combination treatment with anti-inflammatory and neuroprotective agents in experimental autoimmune encephalomyelitis

(2009) Sienmi Du et al.   JOURNAL OF NEUROIMMUNOLOGY

Estrogen receptor β ligands: Recent advances and biomedical applications

(2009) Filippo Minutolo et al.   MEDICINAL RESEARCH REVIEWS

The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17–producing effector T helper cells in vivo

(2009) Mandy J McGeachy et al.   NATURE IMMUNOLOGY

The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins

(2008) Marc Veldhoen et al.   NATURE

IL-21 and TGF-β are required for differentiation of human TH17 cells

(2008) Li Yang et al.   NATURE

The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells

(2008) Aurelie T Bauquet et al.   NATURE IMMUNOLOGY

Interleukin-17 Production in Central Nervous System-Infiltrating T Cells and Glial Cells Is Associated with Active Disease in Multiple Sclerosis

(2007) John S. Tzartos et al.   AMERICAN JOURNAL OF PATHOLOGY