Tolerogenic Phenotype of IFN-γ–Induced IDO+Dendritic Cells Is Maintained via an Autocrine IDO–Kynurenine/AhR–IDO Loop

Regulatory Rebound in IL-12–Treated Tumors Is Driven by Uncommitted Peripheral Regulatory T Cells

(2015) Qingsheng Li et al.   JOURNAL OF IMMUNOLOGY

Constitutive IDO expression in human cancer is sustained by an autocrine signaling loop involving IL-6, STAT3 and the AHR

(2015) Ulrike M. Litzenburger et al.   Oncotarget

IDO2 is critical for IDO1-mediated T-cell regulation and exerts a non-redundant function in inflammation

(2014) Richard Metz et al.   INTERNATIONAL IMMUNOLOGY

Cutting Edge: Autocrine TGF-  Sustains Default Tolerogenesis by IDO-Competent Dendritic Cells

(2014) M. L. Belladonna et al.   JOURNAL OF IMMUNOLOGY

Aryl hydrocarbon receptor control of a disease tolerance defence pathway

(2014) Alban Bessede et al.   NATURE

Regulation of Expression and Function of IDO in Human Dendritic Cells

(2012) A. Heitger   CURRENT MEDICINAL CHEMISTRY

Indoleamine 2,3-Dioxygenase and Dendritic Cell Tolerogenicity

(2012) Jamie L Harden et al.   IMMUNOLOGICAL INVESTIGATIONS

Nitric oxide short-circuits interleukin-12-mediated tumor regression

(2011) Nejat K. Egilmez et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Dichotomous Effects of IFN-  on Dendritic Cell Function Determine the Extent of IL-12-Driven Antitumor T Cell Immunity

(2011) J. L. Harden et al.   JOURNAL OF IMMUNOLOGY

Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells

(2011) Maria T Pallotta et al.   NATURE IMMUNOLOGY

An Interaction between Kynurenine and the Aryl Hydrocarbon Receptor Can Generate Regulatory T Cells

(2010) J. D. Mezrich et al.   JOURNAL OF IMMUNOLOGY

Aryl hydrocarbon receptor negatively regulates dendritic cell immunogenicity via a kynurenine-dependent mechanism

(2010) N. T. Nguyen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Central Role of IFN -Indoleamine 2,3-Dioxygenase Axis in Regulation of Interleukin-12-Mediated Antitumor Immunity

(2009) T. Gu et al.   CANCER RESEARCH

Aryl hydrocarbon receptor signaling mediates expression of indoleamine 2,3-dioxygenase

(2008) Christoph F.A. Vogel et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS