The ATM Kinase Restrains Joining of Both VDJ Signal and Coding Ends

Restoration of ATM Expression in DNA-PKcs–Deficient Cells Inhibits Signal End Joining

(2016) Jessica A. Neal et al.   JOURNAL OF IMMUNOLOGY

Heat Shock Factor 1: From Fire Chief to Crowd-Control Specialist

(2016) Catherine G. Triandafillou et al.   MOLECULAR CELL

Molecular Mechanism of V(D)J Recombination from Synaptic RAG1-RAG2 Complex Structures

(2015) Heng Ru et al.   CELL

Crystal structure of the V(D)J recombinase RAG1–RAG2

(2015) Min-Sung Kim et al.   NATURE

Role of RAG1 autoubiquitination in V(D)J recombination

(2015) Samarendra K. Singh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The DNA-dependent protein kinase: A multifunctional protein kinase with roles in DNA double strand break repair and mitosis

(2015) Nicholas Jette et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

An Autoregulatory Mechanism Imposes Allosteric Control on the V(D)J Recombinase by Histone H3 Methylation

(2015) Chao Lu et al.   Cell Reports

RAG2 mutants alter DSB repair pathway choice in vivo and illuminate the nature of ‘alternative NHEJ’

(2014) Vered Gigi et al.   NUCLEIC ACIDS RESEARCH

RAG2’s Acidic Hinge Restricts Repair-Pathway Choice and Promotes Genomic Stability

(2013) Marc A. Coussens et al.   Cell Reports

The Response to and Repair of RAG-Mediated DNA Double-Strand Breaks

(2012) Beth A. Helmink et al.   Annual Review of Immunology

Redundant and Nonredundant Functions of ATM and H2AX in    T-Lineage Lymphocytes

(2012) B. Yin et al.   JOURNAL OF IMMUNOLOGY

Real-time monitoring of RAG-catalyzed DNA cleavage unveils dynamic changes in coding end association with the coding end complex

(2012) Guannan Wang et al.   NUCLEIC ACIDS RESEARCH

Repair of Chromosomal RAG-Mediated DNA Breaks by Mutant RAG Proteins Lacking Phosphatidylinositol 3-Like Kinase Consensus Phosphorylation Sites

(2011) E. J. Gapud et al.   JOURNAL OF IMMUNOLOGY

The RAG2 C terminus suppresses genomic instability and lymphomagenesis

(2011) Ludovic Deriano et al.   NATURE

Multiple roles of ATM in monitoring and maintaining DNA integrity

(2010) Frederick A. Derheimer et al.   FEBS LETTERS

Requirement of ATM for Rapid p53 Phosphorylation at Ser46 without Ser/Thr-Gln Sequences

(2010) M. Kodama et al.   MOLECULAR AND CELLULAR BIOLOGY

Autoinhibition of DNA cleavage mediated by RAG1 and RAG2 is overcome by an epigenetic signal in V(D)J recombination

(2010) G. J. Grundy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MRN complex function in the repair of chromosomal Rag-mediated DNA double-strand breaks

(2009) Beth A. Helmink et al.   JOURNAL OF EXPERIMENTAL MEDICINE

H3K4me3 Stimulates the V(D)J RAG Complex for Both Nicking and Hairpinning in trans in Addition to Tethering in cis: Implications for Translocations

(2009) Noriko Shimazaki et al.   MOLECULAR CELL

ATM and p53 are essential in the cell-cycle containment of DNA breaks during V(D)J recombination in vivo

(2009) M E Dujka et al.   ONCOGENE

53BP1 facilitates long-range DNA end-joining during V(D)J recombination

(2008) Simone Difilippantonio et al.   NATURE

Complementary functions of ATM and H2AX in development and suppression of genomic instability

(2008) S. Zha et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA