Engineering of Isogenic Cells Deficient for MR1 with a CRISPR/Cas9 Lentiviral System: Tools To Study Microbial Antigen Processing and Presentation to Human MR1-Restricted T Cells

Diversity of T Cells Restricted by the MHC Class I-Related Molecule MR1 Facilitates Differential Antigen Recognition

(2016) Nicholas A. Gherardin et al.   IMMUNITY

The T cell antigen receptor: the Swiss army knife of the immune system

(2015) M. Attaf et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

MR1 presentation of vitamin B-based metabolite ligands

(2015) Hamish EG McWilliam et al.   CURRENT OPINION IN IMMUNOLOGY

Mucosal-associated invariant T cell alterations in obese and type 2 diabetic patients

(2015) Isabelle Magalhaes et al.   JOURNAL OF CLINICAL INVESTIGATION

T Cell Cross-Reactivity between a Highly Immunogenic EBV Epitope and a Self-Peptide Naturally Presented by HLA-B*18:01+Cells

(2015) Melissa J. Rist et al.   JOURNAL OF IMMUNOLOGY

In Vitro and In Vivo Analysis of the Gram-Negative Bacteria–Derived Riboflavin Precursor Derivatives Activating Mouse MAIT Cells

(2015) Claire Soudais et al.   JOURNAL OF IMMUNOLOGY

In vivo genome editing using Staphylococcus aureus Cas9

(2015) F. Ann Ran et al.   NATURE

MR1-restricted MAIT cells display ligand discrimination and pathogen selectivity through distinct T cell receptor usage

(2014) Marielle C. Gold et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The IL-17A-Producing CD8 + T-Cell Population in Psoriatic Lesional Skin Comprises Mucosa-Associated Invariant T Cells and Conventional T Cells

(2014) Marcel B.M. Teunissen et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

T-cell activation by transitory neo-antigens derived from distinct microbial pathways

(2014) Alexandra J. Corbett et al.   NATURE

Improving CRISPR-Cas nuclease specificity using truncated guide RNAs

(2014) Yanfang Fu et al.   NATURE BIOTECHNOLOGY

CRISPR-Cas systems for editing, regulating and targeting genomes

(2014) Jeffry D Sander et al.   NATURE BIOTECHNOLOGY

Cas9 as a versatile tool for engineering biology

(2013) Prashant Mali et al.   NATURE METHODS

MAIT cells are critical for optimal mucosal immune responses during in vivo pulmonary bacterial infection

(2013) A. Meierovics et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RNA-Guided Human Genome Engineering via Cas9

(2013) P. Mali et al.   SCIENCE

Multiplex Genome Engineering Using CRISPR/Cas Systems

(2013) L. Cong et al.   SCIENCE

MAIT Cells Detect and Efficiently Lyse Bacterially-Infected Epithelial Cells

(2013) Lionel Le Bourhis et al.   PLoS Pathogens

Polyclonal Mucosa-Associated Invariant T Cells Have Unique Innate Functions in Bacterial Infection

(2012) Wei-Jen Chua et al.   INFECTION AND IMMUNITY

Abrogation of Src Homology Region 2 Domain-Containing Phosphatase 1 in Tumor-Specific T Cells Improves Efficacy of Adoptive Immunotherapy by Enhancing the Effector Function and Accumulation of Short-Lived Effector T Cells In Vivo

(2012) I. M. Stromnes et al.   JOURNAL OF IMMUNOLOGY

Human thymic MR1-restricted MAIT cells are innate pathogen-reactive effectors that adapt following thymic egress

(2012) M C Gold et al.   Mucosal Immunology

MR1 presents microbial vitamin B metabolites to MAIT cells

(2012) Lars Kjer-Nielsen et al.   NATURE

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

(2012) M. Jinek et al.   SCIENCE

Innate signals overcome acquired TCR signaling pathway regulation and govern the fate of human CD161hi CD8 + semi-invariant T cells

(2011) C. J. Turtle et al.   BLOOD

Mucosal-associated invariant T cells regulate Th1 response in multiple sclerosis

(2011) Yusei Miyazaki et al.   INTERNATIONAL IMMUNOLOGY

A robust, high-throughput assay to determine the phagocytic activity of clinical antibody samples

(2010) Margaret E. Ackerman et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Antimicrobial activity of mucosal-associated invariant T cells

(2010) Lionel Le Bourhis et al.   NATURE IMMUNOLOGY

Human Mucosal Associated Invariant T Cells Detect Bacterially Infected Cells

(2010) Marielle C. Gold et al.   PLOS BIOLOGY

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS