Sema3e/Plexin D1 Modulates Immunological Synapse and Migration of Thymocytes by Rap1 Inhibition

CCR4 promotes medullary entry and thymocyte–dendritic cell interactions required for central tolerance

(2015) Zicheng Hu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Detection of Rare Antigen-Presenting Cells through T Cell-Intrinsic Meandering Motility, Mediated by Myo1g

(2014) Audrey Gérard et al.   CELL

An image-based RNAi screen identifies SH3BP1 as a key effector of Semaphorin 3E–PlexinD1 signaling

(2014) Aleksandra Tata et al.   JOURNAL OF CELL BIOLOGY

Stable Interactions and Sustained TCR Signaling Characterize Thymocyte–Thymocyte Interactions that Support Negative Selection

(2014) Heather J. Melichar et al.   JOURNAL OF IMMUNOLOGY

 PIX RhoGEF Supports Positive Selection by Restraining Migration and Promoting Arrest of Thymocytes

(2014) M. Korthals et al.   JOURNAL OF IMMUNOLOGY

Quantitative and temporal requirements revealed for Zap70 catalytic activity during T cell development

(2014) Byron B Au-Yeung et al.   NATURE IMMUNOLOGY

Distinct phases in the positive selection of CD8+ T cells distinguished by intrathymic migration and T-cell receptor signaling patterns

(2014) J. O. Ross et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic dissection of plexin signaling in vivo

(2014) Thomas Worzfeld et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dendritic Cells Regulate High-Speed Interstitial T Cell Migration in the Lymph Node via LFA-1/ICAM-1

(2013) T. Katakai et al.   JOURNAL OF IMMUNOLOGY

Antigen-Specific Suppression and Immunological Synapse Formation by Regulatory T Cells Require the Mst1 Kinase

(2013) Takashi Tomiyama et al.   PLoS One

Dynamic control of  1 integrin adhesion by the plexinD1-sema3E axis

(2013) Y. I. Choi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct Temporal Patterns of T Cell Receptor Signaling During Positive Versus Negative Selection in Situ

(2013) H. J. Melichar et al.   Science Signaling

Generalized Lévy walks and the role of chemokines in migration of effector CD8+ T cells

(2012) Tajie H. Harris et al.   NATURE

Plexin-B2 and Plexin-D1 in Dendritic Cells: Expression and IL-12/IL-23p40 Production

(2012) Eda K. Holl et al.   PLoS One

Plexins Are GTPase-Activating Proteins for Rap and Are Activated by Induced Dimerization

(2012) Y. Wang et al.   Science Signaling

Mst1 regulates integrin-dependent thymocyte trafficking and antigen recognition in the thymus

(2012) Yoshihiro Ueda et al.   Nature Communications

Rap1A regulates generation of T regulatory cells via LFA-1-dependent and LFA-1-independent mechanisms

(2010) Lequn Li et al.   CELLULAR IMMUNOLOGY

Semaphorin 3E Initiates Antiangiogenic Signaling through Plexin D1 by Regulating Arf6 and R-Ras

(2010) A. Sakurai et al.   MOLECULAR AND CELLULAR BIOLOGY

Regulation of thymocyte positive selection and motility by GIT2

(2010) Hyewon Phee et al.   NATURE IMMUNOLOGY

Functional Anatomy of T Cell Activation and Synapse Formation

(2009) David R. Fooksman et al.   Annual Review of Immunology

Rap1 controls lymphocyte adhesion cascade and interstitial migration within lymph nodes in RAPL-dependent and -independent manners

(2009) Y. Ebisuno et al.   BLOOD

Plexin-B1 is a GTPase activating protein for M-Ras, remodelling dendrite morphology

(2009) Yasuhiro Saito et al.   EMBO REPORTS

Differential Contribution of Chemotaxis and Substrate Restriction to Segregation of Immature and Mature Thymocytes

(2009) Lauren I. Richie Ehrlich et al.   IMMUNITY

Different Requirement for Rnd GTPases of R-Ras GAP Activity of Plexin-C1 and Plexin-D1

(2009) Kanami Uesugi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Specificity of sensory–motor connections encoded by Sema3e–Plxnd1 recognition

(2009) Eline Pecho-Vrieseling et al.   NATURE

Regulation of conformer-specific activation of the integrin LFA-1 by a chemokine-triggered Rho signaling module

(2009) Matteo Bolomini-Vittori et al.   NATURE IMMUNOLOGY

The impact of negative selection on thymocyte migration in the medulla

(2009) Marie Le Borgne et al.   NATURE IMMUNOLOGY

PlexinD1 Glycoprotein Controls Migration of Positively Selected Thymocytes into the Medulla

(2008) Young I. Choi et al.   IMMUNITY