Scutellarin alleviates lipopolysaccharide-provoked septic nephrotoxicity via attenuation of inflammatory and oxidative events and mitochondrial dysfunction

Mitochondrial Quality Control: A Pathophysiological Mechanism and Therapeutic Target for Stroke

(2022) Miaoxian Yang et al.   Frontiers in Molecular Neuroscience

Mitochondria-derived reactive oxygen species are involved in renal cell ferroptosis during lipopolysaccharide-induced acute kidney injury

(2022) Nan-Nan Liang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The pathological role of damaged organelles in renal tubular epithelial cells in the progression of acute kidney injury

(2022) Zixian Li et al.   Cell Death Discovery

Therapeutic effect of lycopene in lipopolysaccharide nephrotoxicity through alleviation of mitochondrial dysfunction, inflammation, and oxidative stress

(2022) Sepide Salari et al.   MOLECULAR BIOLOGY REPORTS

Scutellarin protects the kidney from ischemia/reperfusion injury by targeting Nrf2

(2022) Jie Dai et al.   NEPHROLOGY

Scutellarin attenuates doxorubicin-induced oxidative stress, DNA damage, mitochondrial dysfunction, apoptosis and autophagy in H9c2 cells, cardiac fibroblasts and HUVECs

(2022) Li Zhou et al.   TOXICOLOGY IN VITRO

Sulfated Galactofucan from Sargassum Thunbergii Attenuates Atherosclerosis by Suppressing Inflammation Via the TLR4/MyD88/NF-κB Signaling Pathway

(2022) Kefu Zhu et al.   CARDIOVASCULAR DRUGS AND THERAPY

Protective Activities of Scutellarin against Alcohol‐Induced Acute Kidney Injury

(2022) Qiankun Yang et al.   CHEMISTRY & BIODIVERSITY

Comparative effects of five polymethoxyflavones purified from Citrus tangerina on inflammation and cancer

(2022) Qiyang Chen et al.   Frontiers in Nutrition

Scutellarin ameliorates high glucose-induced vascular endothelial cells injury by activating PINK1/Parkin-mediated mitophagy

(2021) Junxiao Xi et al.   JOURNAL OF ETHNOPHARMACOLOGY

Protective role of scutellarin on LPS induced – Acute lung injury and regulation of apoptosis, oxidative stress and reduction of mitochondrial dysfunction

(2021) Daosheng Fan et al.   SAUDI JOURNAL OF BIOLOGICAL SCIENCES

Recent advances in the pharmacological management of sepsis-associated acute kidney injury

(2021) Kambiz Kalantari et al.   Expert Review of Clinical Pharmacology

Disulfiram attenuates lipopolysaccharide-induced acute kidney injury by suppressing oxidative stress and NLRP3 inflammasome activation in mice

(2021) Jie Huang et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

All‑trans retinoic acid promotes macrophage phagocytosis and decreases inflammation via inhibiting CD14/TLR4 in acute lung injury

(2021) Shuangxue Li et al.   Molecular Medicine Reports

Maresin 1 Attenuates Lipopolysaccharide-Induced Acute Kidney Injury via Inhibiting NOX4/ROS/NF-κB Pathway

(2021) Jiameng Li et al.   Frontiers in Pharmacology

Scutellarin Ameliorates Renal Injury via Increasing CCN1 Expression and Suppressing NLRP3 Inflammasome Activation in Hyperuricemic Mice

(2020) Guozheng Li et al.   Frontiers in Pharmacology

Scutellarin Exerts Hypoglycemic and Renal Protective Effects in db/db Mice via the Nrf2/HO-1 Signaling Pathway

(2019) Yange Liu et al.   Oxidative Medicine and Cellular Longevity

Renoprotective effect of scutellarin on cisplatin-induced renal injury in mice: Impact on inflammation, apoptosis, and autophagy

(2019) Chao-Yue Sun et al.   BIOMEDICINE & PHARMACOTHERAPY

S-allyl cysteine protects against lipopolysaccharide-induced acute kidney injury in the C57BL/6 mouse strain: Involvement of oxidative stress and inflammation

(2019) Mohammad-Reza Khajevand-Khazaei et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The effects of Hemiscorpius lepturus induced-acute kidney injury on PGC-1α gene expression: From induction to suppression in mice

(2019) Rana Dizaji et al.   TOXICON

Rutin, a quercetin glycoside, alleviates acute endotoxemic kidney injury in C57BL/6 mice via suppression of inflammation and up-regulation of antioxidants and SIRT1

(2018) Mohammad-Reza Khajevand-Khazaei et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Hydrogen Sulfide Attenuates LPS-Induced Acute Kidney Injury by Inhibiting Inflammation and Oxidative Stress

(2018) Yuhong Chen et al.   Oxidative Medicine and Cellular Longevity

The Nephroprotective Effect of MS-275 on Lipopolysaccharide (LPS)-Induced Acute Kidney Injury by Inhibiting Reactive Oxygen Species (ROS)-Oxidative Stress and Endoplasmic Reticulum Stress

(2018) Haiyue Zhang et al.   MEDICAL SCIENCE MONITOR

Hesperetin, a citrus flavonoid, attenuates testicular damage in diabetic rats via inhibition of oxidative stress, inflammation, and apoptosis

(2018) Alireza Samie et al.   LIFE SCIENCES

Effect of Scutellarin inhibits collagen-induced arthritis through TLR4/NF-κB-mediated inflammation

(2017) Laibo Zhang et al.   Molecular Medicine Reports

The Proteins from Sika deer antler as potential modulators on cisplatin-induced cytotoxicity in human embryonic kidney 293 cells

(2017) Huihai Yang et al.   NATURAL PRODUCT RESEARCH

The protective effects of Ribes diacanthum Pall on cisplatin-induced nephrotoxicity in mice

(2016) Akhtolkhyn Tilyek et al.   JOURNAL OF ETHNOPHARMACOLOGY

Scutellarin protects cardiomyocyte ischemia–reperfusion injury by reducing apoptosis and oxidative stress

(2016) Zhou Wang et al.   LIFE SCIENCES

Renoprotective approaches and strategies in acute kidney injury

(2016) Yuan Yang et al.   PHARMACOLOGY & THERAPEUTICS

CCR5 deficiency increased susceptibility to lipopolysaccharide-induced acute renal injury

(2015) Dong Hun Lee et al.   ARCHIVES OF TOXICOLOGY

Panaxadiol Saponin and Dexamethasone Improve Renal Function in Lipopolysaccharide-Induced Mouse Model of Acute Kidney Injury

(2015) Yan Chen et al.   PLoS One

Anti-Fibrosis Effect of Scutellarin via Inhibition of Endothelial–Mesenchymal Transition on Isoprenaline-Induced Myocardial Fibrosis in Rats

(2014) Hao Zhou et al.   MOLECULES

Animal models of acute renal failure

(2014) Amrit Pal Singh et al.   Pharmacological Reports

Measuring Myeloperoxidase Activity in Biological Samples

(2013) Benjamin Pulli et al.   PLoS One

A Unified Theory of Sepsis-Induced Acute Kidney Injury

(2013) Hernando Gomez et al.   SHOCK

Soy isoflavone attenuates brain mitochondrial oxidative stress induced by beta-amyloid peptides 1-42 injection in lateral cerebral ventricle

(2012) Juan Ding et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Endotoxin Uptake by S1 Proximal Tubular Segment Causes Oxidative Stress in the Downstream S2 Segment

(2011) R. Kalakeche et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Acute and subacute toxicological evaluation of scutellarin in rodents

(2011) Xiaorong Li et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Animal models of sepsis and sepsis-induced kidney injury

(2009) Kent Doi et al.   JOURNAL OF CLINICAL INVESTIGATION

Acute kidney injury in septic shock: clinical outcomes and impact of duration of hypotension prior to initiation of antimicrobial therapy

(2008) Sean M. Bagshaw et al.   INTENSIVE CARE MEDICINE