CD36-Mediated Uptake of Surfactant Lipids by Human Macrophages Promotes Intracellular Growth ofMycobacterium tuberculosis

Design and synthesis of novel anti-tuberculosis agents from the celecoxib pharmacophore

(2015) Santosh B. Salunke et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Characterization of Host and Microbial Determinants in Individuals with Latent Tuberculosis Infection Using a Human Granuloma Model

(2015) Evelyn Guirado et al.   mBio

Novel Inhibitors of Cholesterol Degradation in Mycobacterium tuberculosis Reveal How the Bacterium’s Metabolism Is Constrained by the Intracellular Environment

(2015) Brian C. VanderVen et al.   PLoS Pathogens

Pulmonary Surfactant Protein A Regulates TLR Expression and Activity in Human Macrophages

(2014) L. N. Henning et al.   JOURNAL OF IMMUNOLOGY

In Vivo Characterization of Alveolar and Interstitial Lung Macrophages in Rhesus Macaques: Implications for Understanding Lung Disease in Humans

(2014) Y. Cai et al.   JOURNAL OF IMMUNOLOGY

Protective or Deleterious Role of Scavenger Receptors SR-A and CD36 on Host Resistance to Staphylococcus aureus Depends on the Site of Infection

(2014) Charlène Blanchet et al.   PLoS One

Macrophage immunoregulatory pathways in tuberculosis

(2014) Murugesan V.S. Rajaram et al.   SEMINARS IN IMMUNOLOGY

Global Adaptation to a Lipid Environment Triggers the Dormancy-Related Phenotype of Mycobacterium tuberculosis

(2014) J. G. Rodriguez et al.   mBio

IntracellularMycobacterium tuberculosisExploits Host-derived Fatty Acids to Limit Metabolic Stress

(2013) Wonsik Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Scavenger Receptor CD36 Downmodulates the Early Inflammatory Response while Enhancing Bacterial Phagocytosis during Pneumococcal Pneumonia

(2013) O. Sharif et al.   JOURNAL OF IMMUNOLOGY

Pulmonary surfactant protein A and surfactant lipids upregulate IRAK-M, a negative regulator of TLR-mediated inflammation in human macrophages

(2012) Huy A. Nguyen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Cholesterol Catabolism by Mycobacterium tuberculosis Requires Transcriptional and Metabolic Adaptations

(2012) Jennifer E. Griffin et al.   CHEMISTRY & BIOLOGY

Uptake and Accumulation of Oxidized Low-Density Lipoprotein during Mycobacterium tuberculosis Infection in Guinea Pigs

(2012) Gopinath S. Palanisamy et al.   PLoS One

Cholesterol Is Not an Essential Source of Nutrition for Mycobacterium tuberculosis during Infection

(2011) X. Yang et al.   JOURNAL OF BACTERIOLOGY

Human Lung Hydrolases Delineate Mycobacterium tuberculosis-Macrophage Interactions and the Capacity To Control Infection

(2011) J. Arcos et al.   JOURNAL OF IMMUNOLOGY

Mycobacterium tuberculosis lipomannan blocks TNF biosynthesis by regulating macrophage MAPK-activated protein kinase 2 (MK2) and microRNA miR-125b

(2011) M. V. S. Rajaram et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mycobacterium tuberculosis Uses Host Triacylglycerol to Accumulate Lipid Droplets and Acquires a Dormancy-Like Phenotype in Lipid-Loaded Macrophages

(2011) Jaiyanth Daniel et al.   PLoS Pathogens

CD36 deficiency attenuates experimental mycobacterial infection

(2010) Michael Hawkes et al.   BMC INFECTIOUS DISEASES

Caseation of human tuberculosis granulomas correlates with elevated host lipid metabolism

(2010) Mi-Jeong Kim et al.   EMBO Molecular Medicine

Partial Redundancy of the Pattern Recognition Receptors, Scavenger Receptors, and C-Type Lectins for the Long-Term Control of Mycobacterium tuberculosis Infection

(2010) N. Court et al.   JOURNAL OF IMMUNOLOGY

Mycobacterium tuberculosis Activates Human Macrophage Peroxisome Proliferator-Activated Receptor   Linking Mannose Receptor Recognition to Regulation of Immune Responses

(2010) M. V. S. Rajaram et al.   JOURNAL OF IMMUNOLOGY

Targeted PPARγ deficiency in alveolar macrophages disrupts surfactant catabolism

(2010) Anna D. Baker et al.   JOURNAL OF LIPID RESEARCH

Membrane Fatty Acid Transporters as Regulators of Lipid Metabolism: Implications for Metabolic Disease

(2010) Jan F. C. Glatz et al.   PHYSIOLOGICAL REVIEWS

Optimisation of Bioluminescent Reporters for Use with Mycobacteria

(2010) Nuria Andreu et al.   PLoS One

Lung environment determines unique phenotype of alveolar macrophages

(2009) Amanda M. Guth et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

A Thiolase of Mycobacterium tuberculosis Is Required for Virulence and Production of Androstenedione and Androstadienedione from Cholesterol

(2009) N. M. Nesbitt et al.   INFECTION AND IMMUNITY

CD36 and TLR Interactions in Inflammation and Phagocytosis: Implications for Malaria

(2009) L. K. Erdman et al.   JOURNAL OF IMMUNOLOGY

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

(2009) Cameron R Stewart et al.   NATURE IMMUNOLOGY

Tumor Necrosis Factor Blockers Influence Macrophage Responses toMycobacterium tuberculosis

(2008) James Harris et al.   JOURNAL OF INFECTIOUS DISEASES

Mycobacterial persistence requires the utilization of host cholesterol

(2008) A. K. Pandey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Foamy Macrophages from Tuberculous Patients' Granulomas Constitute a Nutrient-Rich Reservoir for M. tuberculosis Persistence

(2008) Pascale Peyron et al.   PLoS Pathogens