Article
Chemistry, Multidisciplinary
Anindita Dewan, Manashi Sarmah, Prantika Bhattacharjee, Pankaj Bharali, Ashim J. Thakur, Utpal Bora
Summary: This study reports the design, synthesis, and application of naturally occurring cellulose from agro waste pomegranate peel as a novel support for active biogenic Pd nanoparticles for Suzuki-Miyaura and Sonogashira cross-coupling reactions at room temperature. The cellulose matrix enables well dispersion of Pd nanoparticles over the support to generate Pd@cellulose, exhibiting excellent catalytic activity and recyclability under ligand-free mild reaction conditions. The synthesized cellulose nanofibers and Pd-anchored heterogeneous nanofibers were characterized through various analytical techniques.
SUSTAINABLE CHEMISTRY AND PHARMACY
(2021)
Editorial Material
Chemistry, Multidisciplinary
Soji Shimizu
Summary: Porphyrin analogues have attracted intensive investigations due to their rich coordination chemistry and unique optical and electrochemical properties. Among them, subporphyrins, especially the boron-free ones, have long been awaited. Recently, Kim, Osuka, and Song successfully synthesized a boron-free subporphyrin by introducing an exocyclic double bond at the meso-position and subsequent reduction to obtain macrocyclic conjugation. This seminal work will significantly facilitate studies on coordination chemistry and applications in materials science, as the availability of free base porphyrins is crucial for the development of porphyrin chemistry.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Polymer Science
Ryota Iwamori, Ryota Sato, Junpei Kuwabara, Takaki Kanbara
Summary: Nonstoichiometric polyaddition was achieved through Co-catalyzed hydroarylation of diyne monomers with excess 1-(2-pyrimidinyl)pyrrole. The 2-pyrimidinyl substituent acted as a directing group, facilitating intramolecular catalyst transfer and yielding poly(arylenevinylene)s with alkyne terminals and high molecular weight.
Article
Chemistry, Multidisciplinary
Miki B. Kurosawa, Kenta Kato, Kei Muto, Junichiro Yamaguchi
Summary: A deoxygenative transformation method was developed for the synthesis of multiply arylated alkanes from various diarylketones. The method involves a phospha-Brook rearrangement of diarylketones by reacting with diphenylphosphine oxide, followed by palladium-catalyzed cross-couplings or a Friedel-Crafts type alkylation. The method also enables the one-pot conversion from arylcarboxylic acids to diarylmethanes and tetraarylethanes, as well as the synthesis of tetraarylmethane and triphenylethane using sequential coupling reactions.
Article
Chemistry, Multidisciplinary
Angus Olding, Curtis C. Ho, Allan J. Canty, Nigel T. Lucas, James Horne, Alex C. Bissember
Summary: This study reports the synthesis of a family of unprecedented arylpalladium(II) boronates that are kinetically stable at ambient temperature, and their chemical competence in a Suzuki-Miyaura reaction was demonstrated.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Chemistry, Physical
Mahsa Niakan, Majid Masteri-Farahani, Sabah Karimi, Hemayat Shekaari
Summary: The synthesis of biphenyls through the Suzuki-Miyaura coupling reaction remains a challenge in green chemistry. In this study, a heterogeneous Pd catalyst was successfully synthesized using a green approach, allowing for the production of biphenyls in deep eutectic solvents. By incorporating cellulose into the catalyst structure, the catalytic activity was enhanced, leading to high yields of the desired products.
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Article
Chemistry, Physical
Zeinab Ahmadvand, Mehdi Bayat
Summary: This research aims to establish a more suitable reaction pathway and cross-coupling mechanism for the formation of certain derivatives of quinoxaline and benzofuran by comparing the mechanisms of Suzuki-Miyaura and Hiyama cross-coupling reactions. The findings suggest that the Pd-NHC type complex approach is more desirable for the development of regioselective compounds in competition between different types of cross-coupling reactions.
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Review
Chemistry, Multidisciplinary
Francisco G. Blanco, Natalia Hernandez, Virginia Rivero-Buceta, Beatriz Maestro, Jesus M. Sanz, Aranzazu Mato, Ana M. Hernandez-Arriaga, M. Auxiliadora Prieto
Summary: Bacterial biopolymers are naturally occurring materials that can be produced from renewable sources and have diverse chemical structures. They have gained substantial interest in the biomedical field, particularly bacterial cellulose, polyhydroxyalkanoates, and gamma-polyglutamic acid, which are suitable for nanoscale biomedical applications due to their versatility and unique properties. Their production processes can be sustainable and their properties can be further enhanced for biomedical nanomaterial applications through chemical and biotechnological approaches.
Article
Chemistry, Physical
Poonam Nagendra Singh, Mohamed Gamal Mohamed, Swetha V. Chaganti, Santosh U. Sharma, Moshin Ejaz, Jyh-Tsung Lee, Shiao-Wei Kuo
Summary: Three PDI-based CMPs, Py-Ph-Pery, TPE-Ph-Pery, and TPA-Ph-Pery CMPs, were successfully synthesized through a Suzuki-Miyaura coupling reaction. The CMPs exhibited moderate thermal stability and excellent capacitive properties, with Py-Ph-Pery CMP showing a high capacitance of 300 F g(-1) and exceptional cycle stability over 5000 cycles. These findings highlight the potential of these CMPs for reliable and durable energy storage applications.
ACS APPLIED ENERGY MATERIALS
(2023)
Review
Chemistry, Multidisciplinary
Anna-Carin C. Carlsson, Staffan Karlsson, Rachel H. Munday, Matthew R. . Tatton
Summary: Atropisomerism is a stereochemical phenomenon exhibited by molecules with a rotationally restricted sigma bond. Atropisomers exist as a dynamic mixture and can be interconverted without breaking and reforming bonds. They are frequent targets in medicinal chemistry projects due to their axial chirality and unique 3D structures. However, selecting a single atropisomer presents problems such as interconversion and separation challenges. Chromatography, enzymatic or chiral catalysts can be used for separation, but each method has limitations. This Account discusses the successes, failures, and challenges of developing methods for resolution and synthesis of atropisomeric drug candidates.
ACCOUNTS OF CHEMICAL RESEARCH
(2022)
Article
Chemistry, Organic
Peng Lei, Yibo Wang, Caixia Zhang, Yuge Hu, Juntao Feng, Zhiqing Ma, Xili Liu, Roman Szostak, Michal Szostak
Summary: In this study, the Sonogashira cross-coupling of aryl ammonium salts was successfully catalyzed by [Pd(NHC)(3-CF3-An)Cl2]. The catalyst exhibited broad scope and excellent C-N activation selectivity. The replacement of pyridine with aniline as an ancillary ligand in the Pd(II)-NHC complex was proven to be highly effective in stabilizing the catalyst.
Article
Biochemistry & Molecular Biology
Vitor A. S. Almodovar, Augusto C. Tome
Summary: This article presents a convenient two-step synthesis of various DPP dyes from Pigment Red 254, showing large Stokes shifts and high fluorescence quantum yields, which are important properties for their potential use in technical and biological applications.
Article
Chemistry, Multidisciplinary
Hongwei Lin, Huan Yao, Xiyue Gao, Li Zhang, Qionglin Luo, Yuejun Ouyang, Bailin Xiang, Shasha Liu, Dexuan Xiang
Summary: This study presents a novel hypercrosslinked polymer catalyst with high efficiency, cost-effectiveness, and recyclability, characterized by various physicochemical methods. The results demonstrate excellent catalytic performance and stability of the catalyst, showing promising potential for practical applications.
Article
Engineering, Chemical
Hande Barkan-Ozturk, Angelika Menner, Alexander Bismarck, Robert T. Woodward
Summary: Porous polymers with organophosphorus functionalities were synthesized using particle and surfactant stabilized emulsion templates followed by low-cost hypercrosslinking strategies. The resulting polyHIPEs displayed high surface areas and phosphorus concentrations, and showed excellent catalytic performance in a Suzuki-Miyaura coupling reaction. The coarse powder form of the polyHIPEs allowed for easy catalyst recovery and reuse.
CHEMICAL ENGINEERING SCIENCE
(2022)
Article
Chemistry, Applied
Mostafa Ahmed, Mohammed G. Kotp, Tharwat Hassan Mansoure, Rong-Ho Lee, Shiao-Wei Kuo, Ahmed F. M. EL-Mahdy
Summary: In this study, carbazoletethered conjugated microporous polymers were synthesized and showed improved electrochemical capacitance, along with excellent thermal stability and high surface area. These CMPs have potential applications as high-performance supercapacitors in energy storage systems.
MICROPOROUS AND MESOPOROUS MATERIALS
(2022)
Article
Polymer Science
Khaled Beyaz, Carlos Vaca-Garcia, Emeline Vedrenne, Nabila Haddadine, Ahmed Benaboura, Sophie Thiebaud-Roux
INTERNATIONAL JOURNAL OF POLYMER ANALYSIS AND CHARACTERIZATION
(2019)
Article
Chemistry, Multidisciplinary
Pascale de Caro, Matthieu Bandres, Martine Urrutigoity, Christine Cecutti, Sophie Thiebaud-Roux
FRONTIERS IN CHEMISTRY
(2019)
Article
Engineering, Chemical
Ivonne Rodriguez-Donis, Vincent Gerbaud, Sophie Lavoine, Michel Meyer, Sophie Thiebaud-Roux, Alice Dupouyet
CHEMICAL ENGINEERING RESEARCH & DESIGN
(2019)
Article
Chemistry, Multidisciplinary
Clement Giry, David Bertrand, Christine Cecutti, Clarisse Brossard, Ella Moreau, Sophie Thiebaud-Roux, Carlos Vaca-Garcia, Emeline Vedrenne
Review
Chemistry, Medicinal
Gnaore Yoh Toussaint Douhore, Koffi Barthelemy Attioua, Yaya Soro, Faustin Aka Kabran, Landry Claude Ahmont Kablan, Marc Vedrenne, Celine Mathieu, Carlos Vaca-Garcia
Article
Chemistry, Applied
Simon Duthen, Cecile Levasseur-Garcia, Didier Kleiber, Frederic Violleau, Carlos Vaca-Garcia, Satoru Tsuchikawa, Christine Delgado Raynaud, Jean Dayde
Summary: Gelatin, a natural biopolymer obtained from fibrous collagen, is widely used in various industries. Near-infrared (NIR) spectroscopy can accurately and rapidly analyze the moisture content, gel strength, and viscosity of gelatin, providing a competitive advantage. The technique achieved good predictive accuracy for these parameters, with potential applications in industrial conditions.
FOOD HYDROCOLLOIDS
(2021)
Article
Materials Science, Multidisciplinary
Philippe Evon, Laurent Labonne, Elio Padoan, Carlos Vaca-Garcia, Enzo Montoneri, Valter Boero, Michele Negre
Summary: Research indicates that composite pellets made from sunflower protein concentrate, biopolymers, and urea are an effective and eco-friendly controlled-release fertilizer. The biopolymers contribute to increased surface hardness, control of ammonia production, and release of organic nitrogen. This fertilizer is able to supply organic carbon and major nutrients to soil and plants efficiently.
Article
Green & Sustainable Science & Technology
Graeme Rapp, Victor Garcia-Montoto, Brice Bouyssiere, Sophie Thiebaud-Roux, Alejandro Montoya, Richard Trethowan, Peter Pratt, Kevin Mozet, Jean-Francois Portha, Lucie Coniglio
Summary: This study evaluated the dry-purification of biofuel and biolubricants derived from Indian mustard using various natural mineral and organic adsorbents, finding the optimal procedure to remove impurities and meet basic biofuel specifications. The potential of a biorefinery system focused on Indian mustard in contributing to a green circular economy was highlighted, emphasizing the benefits for both farmers and consumers in terms of energy security, healthy food security, job opportunities, and reduced environmental impact.
JOURNAL OF CLEANER PRODUCTION
(2021)
Article
Materials Science, Multidisciplinary
Elio Padoan, Enzo Montoneri, Giorgio Bordiglia, Valter Boero, Marco Ginepro, Philippe Evon, Carlos Vaca-Garcia, Giancarlo Fascella, Michele Negre
Summary: This study addresses environmental problems related to biowaste management, the chemical industry, and agriculture. The results demonstrate that controlled release fertilizers (CRFs) made with a new biopolymer (BP) can mitigate nitrate accumulation in plants and yield high biomass production of safe crops.
Article
Chemistry, Physical
Jing Wang, Ivonne Rodriguez-Donis, Sophie Thiebaud-Roux, Olzhas A. Ibraikulov, Nicolas Leclerc, Patrick Leveque, Vincent Gerbaud, Markus Kohlstaedt, Thomas Heiser
Summary: A new methodology involving prediction of molecular properties and reverse design is proposed for a more efficient and less empirical selection of green and bio-sourced solvents to replace toxic solvents in solution-processed organic photovoltaic devices, resulting in similar or superior photovoltaic performances.
MOLECULAR SYSTEMS DESIGN & ENGINEERING
(2022)
Review
Engineering, Chemical
Mohamad Nehmeh, Ivonne Rodriguez-Donis, Alexandre Cavaco-Soares, Philippe Evon, Vincent Gerbaud, Sophie Thiebaud-Roux
Summary: Edible oil extraction is a significant field that utilizes solvent-assisted extraction to obtain oil and valuable by-products rich in proteins, fibers, minerals, and secondary metabolites. This research reviews the current status of oilseeds, the refining process, alternative solvents, and unconventional processes. These biologically active compounds are essential raw materials for various industries.
Review
Green & Sustainable Science & Technology
Gabriela Espadas-Aldana, Claire Vialle, Jean-Pierre Belaud, Carlos Vaca-Garcia, Caroline Sablayrolles
SUSTAINABLE PRODUCTION AND CONSUMPTION
(2019)
Review
Chemistry, Applied
Xingran Kou, Dongdong Su, Fei Pan, Xiwei Xu, Qingran Meng, Qinfei Ke
Summary: This review provides a systematic discussion of the application of molecular dynamics (MD) simulations in aroma compounds (ACs)/cyclodextrins (CDs) inclusion complexes (ICs). It covers the establishment of the simulation process, parameter selection, model evaluation, and various application cases, summarizing the major achievements and challenges of this method.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Haoyu Yu, Quanbin Zhang, Ammad Ahmad Farooqi, Jing Wang, Yang Yue, Lihua Geng, Ning Wu
Summary: Brown algae are rich in fucoidan, which has been found to have anti-cancer and anti-metastasis effects. Fucoidan inhibits tumor cell growth, proliferation, and metastasis, and also promotes immune responses in the tumor microenvironment.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Liang Dong, Yanan Li, Hailin Cong, Bing Yu, Youqing Shen
Summary: Gene therapy is a revolutionary treatment that requires suitable vectors for protecting and releasing exogenous nucleic acids in target cells. Chitosan, as a non-viral vector, has gained attention due to its good biocompatibility and ability to load large amounts of nucleic acids. This paper summarizes the potential of chitosan and its derivatives as gene delivery vector materials, discusses factors influencing transfection efficiency, performance evaluation, ways to optimize infectious efficiency, and current research development directions. It also provides an outlook on the future prospects of chitosan.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ana Iglesias-Mejuto, Beatriz Magarinos, Tania Ferreira-Goncalves, Ricardo Starbird-Perez, Carmen Alvarez-Lorenzo, Catarina Pinto Reis, Ines Ardao, Carlos A. Garcia-Gonzalez
Summary: This study developed a novel processing strategy to manufacture drug-loaded and personalized aerogels with nanostructures. The aerogels demonstrated bioactivity and antimicrobial effects, promoting bone regeneration and preventing infections in bone tissue engineering.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Zhenxu Shi, Dimei Yang, Yan Zhou, Xinyu Chen, Lin Gan, Jin Huang
Summary: This study proposes a micro-assembly method to improve the photoluminescent properties of crystalline cellulose nanocrystals (CNCs) by organizing them within a sub-micrometer-sized metal-organic framework and coating with TiO2. The TiO2 coating prevents CNC assembly breakdown and allows information to be revealed using screenprinted labels for anti-counterfeiting purposes.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Xuejiao Liu, Bin Fu, Jierong Chen, Zhenyu Sun, Dongdong Zheng, Zhonghua Li, Bing Gu, Ying Zhang, Haojie Lu
Summary: Liver disease is a major cause of global mortality, and identifying biomarkers for diagnosing its progression is crucial for improving outcomes. Targeted mass spectrometry is a powerful tool for verifying biomarker candidates and clinical applications, particularly for glycoproteins translation. However, the limitation of analyzing only one sample per run has become apparent. In this study, a high-throughput intact N-glycopeptides quantification strategy was developed, allowing the validation of 20 samples per run with an average analysis time of 3 minutes per sample. The strategy was applied in a cohort of 461 serum samples and identified a panel of 10 IgG N-glycopeptides that have strong clinical utility in evaluating the severity of liver disease.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Qian Wang, Hao Jiang, Hongli Zhang, Weiqiao Lu, Xiao Wang, Wenfeng Xu, Jia Li, Youjing Lv, Guoyun Li, Chao Cai, Guangli Yu
Summary: This study proposes a novel strategy of antibody-beta-glucan conjugates (AGC) to enhance the antitumor immune response to immune checkpoint blockade (ICB) therapy. AGC demonstrated powerful tumor suppression and promoted interaction between tumor cells and dendritic cells (DCs), thereby enhancing immunotherapeutic benefits.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Chaeyeon Lee, Sojeong Lee, Sang Wook Kang
Summary: The study aims to enhance the properties of porous membranes by addressing the limitations associated with phase separation. By using cellulose acetate and citric acid, the researchers were able to fabricate membranes with improved mechanical strength and thermal stability. The cross-linking effect of citric acid resulted in a more uniform pore structure and higher porosity.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Tejaswini Kolipaka, Giriraj Pandey, Noella Abraham, Dadi A. Srinivasarao, Rajeev Singh Raghuvanshi, P. S. Rajinikanth, Vidya Tickoo, Saurabh Srivastava
Summary: This review focuses on the design and application of polysaccharide-based hydrogel wound dressings, highlighting aspects such as biocompatibility, biodegradability, drug entrapment, moisturizing ability, swelling, and mechanical properties. Additionally, various crosslinking methods and recent developments in stimuli-responsive hydrogels are discussed.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Anqi Xu, Nan Zhang, Shixing Su, Hongyu Shi, Daoqiang Lu, Xifeng Li, Xin Zhang, Xin Feng, Zhuohua Wen, Gengwu Ma, Mengshi Huang, Chi Huang, Yuqi Hu, Hao Yuan, Qinwen Liu, Daogang Guan, Jun Wang, Chuanzhi Duan
Summary: The study presents a one-pot radical polymerization method to fabricate a hydrogel with adhesive properties, which can effectively treat bacterial-infected diabetic wounds and accelerate wound healing.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Montarop Yamabhai, Munthipha Khamphio, Thae Thae Min, Chai Noy Soem, Nguyen Cao Cuong, Waheni Rizki Aprilia, Krisanai Luesukprasert, Karsidete Teeranitayatarn, Atthaphon Maneedaeng, Tina R. Tuveng, Silje B. Lorentzen, Simen Antonsen, Paiboon Jitprasertwong, Vincent G. H. Eijsink
Summary: The study investigates the bioconversion of chitosan into soluble anti-inflammatory chitosan oligosaccharides (CHOS) using an enzyme. The results show that the generated CHOS have anti-inflammatory activity, but the magnitude of the activity depends on the substrate and production process. Different methods of dissolving chitosan also affect the properties of CHOS. The study highlights the importance of quality assurance in CHOS preparations.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Wen Cao, Jiangping Wu, Xinya Zhao, Zixu Li, Jie Yu, Taili Shao, Xuefeng Hou, Lutan Zhou, Chunfei Wang, Guodong Wang, Jun Han
Summary: In this study, a water-soluble polysaccharide (PLP1) was successfully isolated and purified from Pueraria lobata. It was found that PLP1 was composed of specific glycosidic units and exhibited a better free radical-scavenging ability. Moreover, PLP1 effectively protected the liver against acute alcoholic liver disease (ALD) in mice.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ya Su, Yaqian Liu, Xueyan Hu, Yueqi Lu, Jinyuan Zhang, Wenbo Jin, Wang Liu, Yan Shu, Yuen Yee Cheng, Wenfang Li, Yi Nie, Bo Pan, Kedong Song
Summary: A 3D printed scaffold based on carbon dots-curcumin nano-drug release has been developed for drug delivery after breast cancer surgery. The scaffold showed effective inhibition of tumor growth, antibacterial activity, and promotion of wound healing, making it a promising approach for preventing tumor recurrence.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ekaterina Sokolova, Diane Jouanneau, Antonin Chevenier, Murielle Jam, Nathalie Desban, Pierre Colas, Elizabeth Ficko-Blean, Gurvan Michel
Summary: Carrageenans, a compound synthesized in red algae, have various biological properties and are valuable in the pharmaceutical and cosmetic industries. Their fine structure affects wound healing, oxidative processes, hemostasis, and inflammation. Enzymatic modification of carrageenans produces oligosaccharides that bind to natural human serum antibodies and specific antibodies, showing potential for therapeutic applications.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Yan Shi, Miao Yu, Kaijin Qiu, Tiantian Kong, Chunjing Guo, Wenxue Zhang, Daquan Chen, Ming Kong
Summary: In this study, functionalized transfersomes were developed to co-deliver doxorubicin and 1MT towards primary tumors and tumor draining lymph nodes via transdermal administration using microneedles. The results showed that the nano-complexed microneedles exhibited a stronger suppression in tumor growth compared to the intravenous group.
CARBOHYDRATE POLYMERS
(2024)
