The disulfide catalyst QSOX1 maintains the colon mucosal barrier by regulating Golgi glycosyltransferases
Published 2022 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The disulfide catalyst
QSOX1
maintains the colon mucosal barrier by regulating Golgi glycosyltransferases
Authors
Keywords
-
Journal
EMBO JOURNAL
Volume -, Issue -, Pages -
Publisher
EMBO
Online
2022-10-17
DOI
10.15252/embj.2022111869
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Mucus sialylation determines intestinal host-commensal homeostasis
- (2022) Yikun Yao et al. CELL
- An intercrypt subpopulation of goblet cells is essential for colonic mucus barrier function
- (2021) Elisabeth E. L. Nyström et al. SCIENCE
- Aberrant Sialylation in Cancer: Biomarker and Potential Target for Therapeutic Intervention?
- (2021) Silvia Pietrobono et al. Cancers
- Assembly and organization of the N-terminal region of mucin MUC5AC: Indications for structural and functional distinction from MUC5B
- (2021) Jerome Carpenter et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mucins Dynamics in Physiological and Pathological Conditions
- (2021) Hassan Melhem et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Inhibition of fibroblast secreted QSOX1 perturbs extracellular matrix in the tumor microenvironment and decreases tumor growth and metastasis in murine cancer models
- (2020) Tal Feldman et al. Oncotarget
- Lgr5+ telocytes are a signaling source at the intestinal villus tip
- (2020) Keren Bahar Halpern et al. Nature Communications
- Structure and Electron-Transfer Pathway of the Human Methionine Sulfoxide Reductase MsrB3
- (2020) Gabriel Javitt et al. ANTIOXIDANTS & REDOX SIGNALING
- Disulfide Exchange in von Willebrand factor Dimerization in the Golgi
- (2020) Xianchi Dong et al. BLOOD
- Assembly Mechanism of Mucin and von Willebrand Factor Polymers
- (2020) Gabriel Javitt et al. CELL
- Wheat Germ Agglutinin as a Potential Therapeutic Agent for Leukemia
- (2019) Bradley Ryva et al. Frontiers in Oncology
- Intra- and Inter-cellular Rewiring of the Human Colon during Ulcerative Colitis
- (2019) Christopher S. Smillie et al. CELL
- Intestinal Gel-Forming Mucins Polymerize by Disulfide-Mediated Dimerization of D3 Domains
- (2019) Gabriel Javitt et al. JOURNAL OF MOLECULAR BIOLOGY
- A Golgi-associated redox switch regulates catalytic activation and cooperative functioning of ST6Gal-I with B4GalT-I
- (2019) Antti Hassinen et al. Redox Biology
- The C-terminal dimerization domain of the respiratory mucin MUC5B functions in mucin stability and intracellular packaging before secretion
- (2019) Caroline Ridley et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The MUC5B mucin polymer is dominated by repeating structural motifs and its topology is regulated by calcium and pH
- (2019) Gareth W. Hughes et al. Scientific Reports
- Structural and functional role of disulphide bonds and substrate binding residues of the human beta-galactoside alpha-2,3-sialyltransferase 1 (hST3Gal1)
- (2019) Maria Elena Ortiz-Soto et al. Scientific Reports
- Don’t sugarcoat it: How glycocalyx composition influences cancer progression
- (2019) Alexander Buffone et al. JOURNAL OF CELL BIOLOGY
- Hypoxia and Reactive Oxygen Species as Modulators of Endoplasmic Reticulum and Golgi Homeostasis
- (2018) Daniela Mennerich et al. ANTIOXIDANTS & REDOX SIGNALING
- QSOX1 , a novel actor of cardiac protection upon acute stress in mice
- (2018) Anais Caillard et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- A sticky end for gastrointestinal helminths; the role of the mucus barrier
- (2018) C. Sharpe et al. PARASITE IMMUNOLOGY
- High expression of QSOX1 is associated with tumor invasiveness and high grades groups in prostate cancer
- (2018) Jin A. Baek et al. PATHOLOGY RESEARCH AND PRACTICE
- Mucin gel assembly is controlled by a collective action of non-mucin proteins, disulfide bridges, Ca2+-mediated links, and hydrogen bonding
- (2018) Oliver W. Meldrum et al. Scientific Reports
- Mucins and Their Role in Shaping the Functions of Mucus Barriers
- (2018) C.E. Wagner et al. Annual Review of Cell and Developmental Biology
- Quiescin Sulfhydryl Oxidase 1 (QSOX1) Secreted by Lung Cancer Cells Promotes Cancer Metastasis
- (2018) Hye-Jin Sung et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Single-cell transcriptomics of 20 mouse organs creates a Tabula Muris
- (2018) et al. NATURE
- Dextran sodium sulfate colitis murine model: An indispensable tool for advancing our understanding of inflammatory bowel diseases pathogenesis
- (2017) Derrick D Eichele et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Interactions of Intestinal Bacteria with Components of the Intestinal Mucus
- (2017) Jean-Félix Sicard et al. Frontiers in Cellular and Infection Microbiology
- Next-Generation Beneficial Microbes: The Case of Akkermansia muciniphila
- (2017) Patrice D. Cani et al. Frontiers in Microbiology
- Mice lacking sialyltransferase ST3Gal-II develop late-onset obesity and insulin resistance
- (2016) Pablo HH Lopez et al. GLYCOBIOLOGY
- The Densely O-Glycosylated MUC2 Mucin Protects the Intestine and Provides Food for the Commensal Bacteria
- (2016) Liisa Arike et al. JOURNAL OF MOLECULAR BIOLOGY
- QSOX1 expression is associated with aggressive tumor features and reduced survival in breast carcinomas
- (2016) Gøril Knutsvik et al. MODERN PATHOLOGY
- Core 1– and 3–derived O-glycans collectively maintain the colonic mucus barrier and protect against spontaneous colitis in mice
- (2016) K Bergstrom et al. Mucosal Immunology
- Overcoming a species-specificity barrier in development of an inhibitory antibody targeting a modulator of tumor stroma
- (2016) Iris Grossman et al. PROTEIN ENGINEERING DESIGN & SELECTION
- von Willebrand factor is dimerized by protein disulfide isomerase
- (2015) Svenja Lippok et al. BLOOD
- Delivery of a mucin domain enriched in cysteine residues strengthens the intestinal mucous barrier
- (2015) Valérie Gouyer et al. Scientific Reports
- Gut microbiome composition and function in experimental colitis during active disease and treatment-induced remission
- (2014) Michelle G Rooks et al. ISME Journal
- The structure of human α-2,6-sialyltransferase reveals the binding mode of complex glycans
- (2013) Bernd Kuhn et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Enzymatic Basis forN-Glycan Sialylation
- (2013) Lu Meng et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- An Inhibitory Antibody Blocks the First Step in the Dithiol/Disulfide Relay Mechanism of the Enzyme QSOX1
- (2013) Iris Grossman et al. JOURNAL OF MOLECULAR BIOLOGY
- Muc5b is required for airway defence
- (2013) Michelle G. Roy et al. NATURE
- The gastrointestinal mucus system in health and disease
- (2013) Malin E. V. Johansson et al. Nature Reviews Gastroenterology & Hepatology
- Elevated Transcription of the Gene QSOX1 Encoding Quiescin Q6 Sulfhydryl Oxidase 1 in Breast Cancer
- (2013) Mikhail Soloviev et al. PLoS One
- A Secreted Disulfide Catalyst Controls Extracellular Matrix Composition and Function
- (2013) T. Ilani et al. SCIENCE
- Disulphide linkage in mouse ST6Gal-I: determination of linkage positions and mutant analysis
- (2011) Y. Hirano et al. JOURNAL OF BIOCHEMISTRY
- Phylogenetic and Functional Analysis of Histidine Residues Essential for pH-dependent Multimerization of von Willebrand Factor
- (2011) Luke T. Dang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Loss of intestinal core 1–derived O-glycans causes spontaneous colitis in mice
- (2011) Jianxin Fu et al. JOURNAL OF CLINICAL INVESTIGATION
- Disruption of Paneth and goblet cell homeostasis and increased endoplasmic reticulum stress in Agr2−/− mice
- (2009) Fang Zhao et al. DEVELOPMENTAL BIOLOGY
- Analysis of the Plasma Peptidome from Pancreas Cancer Patients Connects a Peptide in Plasma to Overexpression of the Parent Protein in Tumors
- (2009) Kwasi Antwi et al. JOURNAL OF PROTEOME RESEARCH
- Structural insight into mammalian sialyltransferases
- (2009) Francesco V Rao et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- The protein disulfide isomerase AGR2 is essential for production of intestinal mucus
- (2009) S.-W. Park et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Munc13-2−/−baseline secretion defect reveals source of oligomeric mucins in mouse airways
- (2008) Yunxiang Zhu et al. JOURNAL OF PHYSIOLOGY-LONDON
- Aberrant Mucin Assembly in Mice Causes Endoplasmic Reticulum Stress and Spontaneous Inflammation Resembling Ulcerative Colitis
- (2008) Chad K Heazlewood et al. PLOS MEDICINE
- The human PDI family: Versatility packed into a single fold
- (2007) Christian Appenzeller-Herzog et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now