Tirzepatide suppresses palatable food intake by selectively reducing preference for fat in rodents

Glucagon-Like Peptide 1 and Taste Perception: From Molecular Mechanisms to Potential Clinical Implications

(2021) Mojca Jensterle et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The glucose-dependent insulinotropic polypeptide (GIP) regulates body weight and food intake via CNS-GIPR signaling

(2021) Qian Zhang et al.   Cell Metabolism

GIP Receptor Agonism Attenuates GLP-1 Receptor Agonist Induced Nausea and Emesis in Preclinical Models

(2021) Tito Borner et al.   DIABETES

Macronutrient intake, appetite, food preferences and exocrine pancreas function after treatment with short‐ and long‐acting glucagon‐like peptide‐1 receptor agonists in type 2 diabetes

(2021) Daniel R. Quast et al.   DIABETES OBESITY & METABOLISM

Efficacy and safety of a novel dual GIP and GLP-1 receptor agonist tirzepatide in patients with type 2 diabetes (SURPASS-1): a double-blind, randomised, phase 3 trial

(2021) Julio Rosenstock et al.   LANCET

Tirzepatide versus Semaglutide Once Weekly in Patients with Type 2 Diabetes

(2021) Juan P. Frías et al.   NEW ENGLAND JOURNAL OF MEDICINE

Effects of Tirzepatide, a Dual GIP and GLP-1 RA, on Lipid and Metabolite Profiles in Subjects With Type 2 Diabetes

(2021) Valentina Pirro et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Effect of liraglutide on food consumption, appetite sensations and eating behaviours in overweight people with type 1 diabetes

(2020) Marie‐Christine Dubé et al.   DIABETES OBESITY & METABOLISM

How May GIP Enhance the Therapeutic Efficacy of GLP-1?

(2020) Ricardo J. Samms et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Glucagon-like peptide-1 receptor co-agonists for treating metabolic disease

(2020) Laurie L. Baggio et al.   Molecular Metabolism

Stressing the importance of choice: Validity of a preclinical free‐choice high‐caloric diet paradigm to model behavioural, physiological and molecular adaptations during human diet‐induced obesity and metabolic dysfunction

(2019) Margo Slomp et al.   JOURNAL OF NEUROENDOCRINOLOGY

Glucose-Dependent Insulinotropic Polypeptide Receptor-Expressing Cells in the Hypothalamus Regulate Food Intake

(2019) Alice E. Adriaenssens et al.   Cell Metabolism

Glucagon-like peptide 1 (GLP-1)

(2019) T.D. Müller et al.   Molecular Metabolism

Metabolic and gut microbiome changes following GLP-1 or dual GLP-1/GLP-2 receptor agonist treatment in diet-induced obese mice

(2019) Mette Simone Aae Madsen et al.   Scientific Reports

Mechanisms of Action and Therapeutic Application of Glucagon-like Peptide-1

(2018) Daniel J. Drucker   Cell Metabolism

Glucagon-like peptide-1 receptor activation in the ventral tegmental area attenuates cocaine seeking in rats

(2018) Nicole S. Hernandez et al.   NEUROPSYCHOPHARMACOLOGY

Optimized GIP analogs promote body weight lowering in mice through GIPR agonism not antagonism

(2018) Piotr A. Mroz et al.   Molecular Metabolism

LY3298176, a novel dual GIP and GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus: From discovery to clinical proof of concept

(2018) Tamer Coskun et al.   Molecular Metabolism

Liraglutide suppression of caloric intake competes with the intake-promoting effects of a palatable cafeteria diet, but does not impact food or macronutrient selection.

(2017) Kellie M. Hyde et al.   PHYSIOLOGY & BEHAVIOR

GLP-1 and weight loss: unraveling the diverse neural circuitry

(2016) Scott E. Kanoski et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

The Hypothalamic Glucagon-Like Peptide 1 Receptor Is Sufficient but Not Necessary for the Regulation of Energy Balance and Glucose Homeostasis in Mice

(2016) Melissa A. Burmeister et al.   DIABETES

The food intake-suppressive effects of glucagon-like peptide-1 receptor signaling in the ventral tegmental area are mediated by AMPA/kainate receptors

(2013) Elizabeth G. Mietlicki-Baase et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

High-fat diet changes the temporal profile of GLP-1 receptor-mediated hypophagia in rats

(2013) Joram D. Mul et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Alteration of sweet taste in high-fat diet induced obese rats after 4 weeks treatment with exenatide

(2013) Xiao-juan Zhang et al.   PEPTIDES

Unimolecular Dual Incretins Maximize Metabolic Benefits in Rodents, Monkeys, and Humans

(2013) B. Finan et al.   Science Translational Medicine

Effects of liraglutide and sibutramine on food intake, palatability, body weight and glucose tolerance in the gubra DIO-rats

(2012) Gitte Hansen et al.   ACTA PHARMACOLOGICA SINICA

Lipid-mediated release of GLP-1 by mouse taste buds from circumvallate papillae: putative involvement of GPR120 and impact on taste sensitivity

(2012) Céline Martin et al.   JOURNAL OF LIPID RESEARCH

The Glucagon-Like Peptide 1 (GLP-1) Analogue, Exendin-4, Decreases the Rewarding Value of Food: A New Role for Mesolimbic GLP-1 Receptors

(2012) S. L. Dickson et al.   JOURNAL OF NEUROSCIENCE

GIP-Overexpressing Mice Demonstrate Reduced Diet-Induced Obesity and Steatosis, and Improved Glucose Homeostasis

(2012) Su-Jin Kim et al.   PLoS One

Food reward, hyperphagia, and obesity

(2011) Hans-Rudolf Berthoud et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Peripheral and Central GLP-1 Receptor Populations Mediate the Anorectic Effects of Peripherally Administered GLP-1 Receptor Agonists, Liraglutide and Exendin-4

(2011) Scott E. Kanoski et al.   ENDOCRINOLOGY

GLP-1 Neurons in the Nucleus of the Solitary Tract Project Directly to the Ventral Tegmental Area and Nucleus Accumbens to Control for Food Intake

(2011) Amber L. Alhadeff et al.   ENDOCRINOLOGY

The relationship between dietary energy density and energy intake

(2009) Barbara J. Rolls   PHYSIOLOGY & BEHAVIOR