Stressing the importance of choice: Validity of a preclinical free‐choice high‐caloric diet paradigm to model behavioural, physiological and molecular adaptations during human diet‐induced obesity and metabolic dysfunction

Impact of Free-Choice Diets High in Fat and Different Sugars on Metabolic Outcome and Anxiety-Like Behavior in Rats

(2019) Fiona Peris-Sampedro et al.   Obesity

The effects of overnight nutrient intake on hypothalamic inflammation in a free-choice diet-induced obesity rat model

(2018) Evita Belegri et al.   APPETITE

Source of dietary sucrose influences development of leptin resistance in male and female rats

(2018) Ruth B. S. Harris   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Is leptin resistance the cause or the consequence of diet-induced obesity?

(2018) Kathy C. G. de Git et al.   INTERNATIONAL JOURNAL OF OBESITY

Leptin and the maintenance of elevated body weight

(2018) Warren W. Pan et al.   NATURE REVIEWS NEUROSCIENCE

Signalling from the periphery to the brain that regulates energy homeostasis

(2018) Ki-Suk Kim et al.   NATURE REVIEWS NEUROSCIENCE

A Free-Choice High-Fat High-Sugar Diet Alters Day–Night Per2 Gene Expression in Reward-Related Brain Areas in Rats

(2018) Aurea Susana Blancas-Velazquez et al.   Frontiers in Endocrinology

Genetic identification of leptin neural circuits in energy and glucose homeostases

(2018) Jie Xu et al.   NATURE

Development of leptin resistance in sucrose drinking rats is associated with consuming carbohydrate-containing solutions and not calorie-free sweet solution

(2018) Ruth B.S. Harris   APPETITE

One-week exposure to a free-choice high-fat high-sugar diet does not disrupt blood–brain barrier permeability in fed or overnight fasted rats

(2017) M. Rijnsburger et al.   NUTRITIONAL NEUROSCIENCE

Fructose Consumption, Lipogenesis, and Non-Alcoholic Fatty Liver Disease

(2017) et al.   Nutrients

Effects of Fat and Sugar, Either Consumed or Infused toward the Brain, on Hypothalamic ER Stress Markers

(2017) Evita Belegri et al.   Frontiers in Neuroscience

Effect of high-fat diets on mood and learning performance in adolescent mice

(2016) Danila Del Rio et al.   BEHAVIOURAL BRAIN RESEARCH

Trends in Obesity Prevalence Among Children and Adolescents in the United States, 1988-1994 Through 2013-2014

(2016) Cynthia L. Ogden et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Differential effects of hypercaloric choice diets on insulin sensitivity in rats

(2016) Charlene Diepenbroek et al.   JOURNAL OF ENDOCRINOLOGY

In vivo and in vitro evidence that chronic activation of the hexosamine biosynthetic pathway interferes with leptin-dependent STAT3 phosphorylation

(2015) Arthur D. Zimmerman et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Leptin resistance in diet-induced obesity: the role of hypothalamic inflammation

(2015) K. C. G. de Git et al.   Obesity Reviews

Hexosamine biosynthetic pathway activity in leptin resistant sucrose-drinking rats

(2015) Ruth B.S. Harris et al.   PHYSIOLOGY & BEHAVIOR

Enhanced flavor–nutrient conditioning in obese rats on a high-fat, high-carbohydrate choice diet

(2015) Hallie S. Wald et al.   PHYSIOLOGY & BEHAVIOR

Immobility in the forced swim test is adaptive and does not reflect depression

(2015) Marc L. Molendijk et al.   PSYCHONEUROENDOCRINOLOGY

Maltodextrin can produce similar metabolic and cognitive effects to those of sucrose in the rat☆

(2014) Michael D. Kendig et al.   APPETITE

Timing of fat and liquid sugar intake alters substrate oxidation and food efficiency in male Wistar rats

(2014) Johanneke E. Oosterman et al.   CHRONOBIOLOGY INTERNATIONAL

Hypercaloric diets with increased meal frequency, but not meal size, increase intrahepatic triglycerides: A randomized controlled trial

(2014) Karin E. Koopman et al.   HEPATOLOGY

Prevalence of Childhood and Adult Obesity in the United States, 2011-2012

(2014) Cynthia L. Ogden et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Neuropeptide Y and Leptin Sensitivity is Dependent on Diet Composition

(2014) J. K. van den Heuvel et al.   JOURNAL OF NEUROENDOCRINOLOGY

Differential Modulation of Arcuate Nucleus and Mesolimbic Gene Expression Levels by Central Leptin in Rats on Short-Term High-Fat High-Sugar Diet

(2014) José K. van den Heuvel et al.   PLoS One

Chronic variable stress improves glucose tolerance in rats with sucrose-induced prediabetes

(2014) Amy E.B. Packard et al.   PSYCHONEUROENDOCRINOLOGY

Trends in sugar-sweetened beverage consumption among youth and adults in the United States: 1999–2010

(2013) Brian K Kit et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

High-fat diet acutely affects circadian organisation and eating behavior

(2013) Julie S. Pendergast et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

The snacking rat as model of human obesity: effects of a free-choice high-fat high-sugar diet on meal patterns

(2013) S E la Fleur et al.   INTERNATIONAL JOURNAL OF OBESITY

Altered Feeding Patterns in Rats Exposed to a Palatable Cafeteria Diet: Increased Snacking and Its Implications for Development of Obesity

(2013) Sarah I. Martire et al.   PLoS One

Metabolic disturbances connecting obesity and depression

(2013) Cecile Hryhorczuk et al.   Frontiers in Neuroscience

Changes in glucose tolerance and leptin responsiveness of rats offered a choice of lard, sucrose, and chow

(2012) Ruth B. S. Harris et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Time-Restricted Feeding without Reducing Caloric Intake Prevents Metabolic Diseases in Mice Fed a High-Fat Diet

(2012) Megumi Hatori et al.   Cell Metabolism

Diet-induced obesity promotes depressive-like behaviour that is associated with neural adaptations in brain reward circuitry

(2012) S Sharma et al.   INTERNATIONAL JOURNAL OF OBESITY

Adaptations in brain reward circuitry underlie palatable food cravings and anxiety induced by high-fat diet withdrawal

(2012) S Sharma et al.   INTERNATIONAL JOURNAL OF OBESITY

High fat/carbohydrate ratio but not total energy intake induces lower striatal dopamine D2/3 receptor availability in diet-induced obesity

(2012) E van de Giessen et al.   INTERNATIONAL JOURNAL OF OBESITY

Free-Choice and No-Choice High-Fat Diets Affect Striatal Dopamine D2/3 Receptor Availability, Caloric Intake, and Adiposity

(2012) Elsmarieke van de Giessen et al.   Obesity

Dietary Obesity Caused by a Specific Circadian Eating Pattern

(2011) Niloofar Hariri et al.   CHRONOBIOLOGY INTERNATIONAL

Impaired CNS Leptin Action Is Implicated in Depression Associated with Obesity

(2011) Nobuko Yamada et al.   ENDOCRINOLOGY

An overview on how components of the melanocortin system respond to different high energy diets

(2011) José K. van den Heuvel et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

High-fat diet selectively protects against the effects of chronic social stress in the mouse

(2011) B.C. Finger et al.   NEUROSCIENCE

Differential effects of chow and purified diet on the consumption of sucrose solution and lard and the development of obesity

(2011) John W. Apolzan et al.   PHYSIOLOGY & BEHAVIOR

The temporal impact of chronic intermittent psychosocial stress on high-fat diet-induced alterations in body weight

(2011) Beate C. Finger et al.   PSYCHONEUROENDOCRINOLOGY

Diet-induced obesity blunts the behavioural effects of ghrelin: studies in a mouse-progressive ratio task

(2011) Beate C. Finger et al.   PSYCHOPHARMACOLOGY

Lower striatal dopamine D2/3 receptor availability in obese compared with non-obese subjects

(2011) Barbara A de Weijer et al.   EJNMMI Research

Snacking is associated with reduced risk of overweight and reduced abdominal obesity in adolescents: National Health and Nutrition Examination Survey (NHANES) 1999–2004

(2010) Debra R Keast et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Overweight, Obesity, and Depression

(2010) Floriana S. Luppino et al.   ARCHIVES OF GENERAL PSYCHIATRY

Circadian disruption and metabolic disease: Findings from animal models

(2010) Deanna Marie Arble et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

A free-choice high-fat high-sugar diet induces glucose intolerance and insulin unresponsiveness to a glucose load not explained by obesity

(2010) S E la Fleur et al.   INTERNATIONAL JOURNAL OF OBESITY

Rodent Models for Metabolic Syndrome Research

(2010) Sunil K. Panchal et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

High-fat diet-induced obesity in animal models

(2010) Niloofar Hariri et al.   NUTRITION RESEARCH REVIEWS

Will Work for Snack Food: The Association of BMI and Snack Reinforcement

(2010) Janneke C.A.H. Giesen et al.   Obesity

Wheel running eliminates high-fat preference and enhances leptin signaling in the ventral tegmental area

(2010) P.J. Scarpace et al.   PHYSIOLOGY & BEHAVIOR

Pleasurable behaviors reduce stress via brain reward pathways

(2010) Y. M. Ulrich-Lai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The economic impact of obesity in the United States

(2010) Ross Hammond et al.   Diabetes Metabolic Syndrome and Obesity-Targets and Therapy

A free-choice high-fat high-sugar diet induces changes in arcuate neuropeptide expression that support hyperphagia

(2009) S E la Fleur et al.   INTERNATIONAL JOURNAL OF OBESITY

Palatable cafeteria diet ameliorates anxiety and depression-like symptoms following an adverse early environment

(2009) Jayanthi Maniam et al.   PSYCHONEUROENDOCRINOLOGY

Withdrawal from free-choice high-fat high-sugar diet induces craving only in obesity-prone animals

(2009) Chris Pickering et al.   PSYCHOPHARMACOLOGY

How emotions affect eating: A five-way model

(2007) Michael Macht   APPETITE