Tapinarof for the treatment of psoriasis

One-year safety and efficacy of tapinarof cream for the treatment of plaque psoriasis: Results from the PSOARING 3 trial

(2022) Bruce Strober et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

The mode of action of tapinarof may not solely depend on the activation of cutaneous AHR signaling but also on its antimicrobial activity

(2021) Thomas Haarmann-Stemmann et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Interleukin-17 and Interleukin-23: A Narrative Review of Mechanisms of Action in Psoriasis and Associated Comorbidities

(2021) Alan Menter et al.   Dermatology and Therapy

Psoriasis

(2021) Christopher E M Griffiths et al.   LANCET

Anti-Inflammatory and Pro-Differentiating Properties of the Aryl Hydrocarbon Receptor Ligands NPD-0614-13 and NPD-0614-24: Potential Therapeutic Benefits in Psoriasis

(2021) Giorgia Cardinali et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Tapinarof cream 1% once daily and benvitimod 1% twice daily are 2 distinct topical medications

(2021) Linda Stein Gold et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Reply to: Tapinarof cream 1% once daily and benvitimod 1% twice daily are two distinct topical medications

(2021) Joy Assaf et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Phase 3 Trials of Tapinarof Cream for Plaque Psoriasis

(2021) Mark G. Lebwohl et al.   NEW ENGLAND JOURNAL OF MEDICINE

Role of AHR Ligands in Skin Homeostasis and Cutaneous Inflammation

(2021) Nieves Fernández-Gallego et al.   Cells

A novel topical treatment for plaque psoriasis: Benvitimod/tapinarof

(2021) Jianzhong Zhang et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Bacterial Autoimmune Drug Metabolism Transforms an Immunomodulator into Structurally and Functionally Divergent Antibiotics

(2020) Hyun Bong Park et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Phase IIb, Randomized Clinical Trial of Tapinarof Cream for the Treatment of Plaque Psoriasis: Secondary Efficacy and Patient-Reported Outcomes

(2020) Linda Stein Gold et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Tapinarof in the treatment of psoriasis: A review of the unique mechanism of action of a novel therapeutic aryl hydrocarbon receptor–modulating agent

(2020) Robert Bissonnette et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Aryl Hydrocarbon Receptor in Atopic Dermatitis and Psoriasis

(2019) Masutaka Furue et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Aryl Hydrocarbon Receptor in Cutaneous Vascular Endothelial Cells Restricts Psoriasis Development by Negatively Regulating Neutrophil Recruitment

(2019) Zhenlai Zhu et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

In situ bio-distribution and residency of a topical anti-inflammatory using fluorescence lifetime imaging microscopy

(2018) A. Alex et al.   BRITISH JOURNAL OF DERMATOLOGY

Aryl hydrocarbon receptor (AhR) a possible target for the treatment of skin disease

(2018) Maddalena Napolitano et al.   MEDICAL HYPOTHESES

How to improve adherence to treatment in patients with mild-to-moderate psoriasis

(2018) Stefano Piaserico et al.   GIORNALE ITALIANO DI DERMATOLOGIA E VENEREOLOGIA

A Phase 2, Randomized Dose-Finding Study of Tapinarof (GSK2894512 Cream) for the Treatment of Plaque Psoriasis

(2018) Kevin Robbins et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Tapinarof Is a Natural AhR Agonist that Resolves Skin Inflammation in Mice and Humans

(2017) Susan H. Smith et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Psoriasis

(2016) Jacqueline E. Greb et al.   Nature Reviews Disease Primers

The Janus-Faced Role of Aryl Hydrocarbon Receptor Signaling in the Skin: Consequences for Prevention and Treatment of Skin Disorders

(2015) Thomas Haarmann-Stemmann et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Activation of the Aryl Hydrocarbon Receptor Dampens the Severity of Inflammatory Skin Conditions

(2014) Paola Di Meglio et al.   IMMUNITY

AHR: Making the Keratinocytes Thick Skinned

(2014) Marco Colonna   IMMUNITY

Adherence to topical treatment in psoriasis: a systematic literature review

(2012) S. Devaux et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY