Recent advances of smart AIEgens for photoacoustic imaging and phototherapy

Recent advances in aggregation-induced emission luminogens in photoacoustic imaging

(2022) Pei Li et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Bioorthogonal Coordination Polymer Nanoparticles with Aggregation‐Induced Emission for Deep Tumor‐Penetrating Radio‐ and Radiodynamic Therapy

(2021) Jingjing Liu et al.   ADVANCED MATERIALS

Photoacoustic Imaging and Photothermal Therapy of Semiconducting Polymer Nanoparticles: Signal Amplification and Second Near‐Infrared Construction

(2021) Xu Zhen et al.   Small

Multifunctional Organic Fluorescent Probe with Aggregation-Induced Emission Characteristics: Ultrafast Tumor Monitoring, Two-Photon Imaging, and Image-Guide Photodynamic Therapy

(2021) Haijun Ma et al.   ACS Applied Materials & Interfaces

Recent Advances in Polymeric Nanoparticles for Enhanced Fluorescence and Photoacoustic Imaging

(2021) Sing Yee Ong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Two-Photon Near-Infrared AIE Luminogens as Multifunctional Gene Carriers for Cancer Theranostics

(2021) Fang Tang et al.   ACS Applied Materials & Interfaces

A Diradicaloid Small Molecular Nanotheranostic with Strong Near-Infrared Absorbance for Effective Cancer Photoacoustic Imaging and Photothermal Therapy

(2021) Xiaozhen Li et al.   ACS Applied Materials & Interfaces

One-for-All Phototheranostic Agent Based on Aggregation-Induced Emission Characteristics for Multimodal Imaging-Guided Synergistic Photodynamic/Photothermal Cancer Therapy

(2021) Luqi Liu et al.   ACS Applied Materials & Interfaces

Pillar[5]arene‐Modified Gold Nanorods as Nanocarriers for Multi‐Modal Imaging‐Guided Synergistic Photodynamic‐Photothermal Therapy

(2021) Nan Song et al.   ADVANCED FUNCTIONAL MATERIALS

Photoactivated nanomotors via aggregation induced emission for enhanced phototherapy

(2021) Shoupeng Cao et al.   Nature Communications

Organic Semiconducting Macromolecular Dyes for NIR‐II Photoacoustic Imaging and Photothermal Therapy

(2021) Chao Yin et al.   ADVANCED FUNCTIONAL MATERIALS

One-for-all phototheranostics: Single component AIE dots as multi-modality theranostic agent for fluorescence-photoacoustic imaging-guided synergistic cancer therapy

(2021) Haifei Wen et al.   BIOMATERIALS

Aza-BODIPY based probe for photoacoustic imaging of ONOO− in vivo

(2021) Danghui Ma et al.   CHINESE CHEMICAL LETTERS

Sensitive Mechanofluorochromic Carbon Dot‐Based AIEgens: Promising Reporting Components for Self‐Sensing Plastics

(2021) Min Ge et al.   Advanced Optical Materials

Multifunctional AIE iridium (III) photosensitizer nanoparticles for two-photon-activated imaging and mitochondria targeting photodynamic therapy

(2021) Xuzi Cai et al.   JOURNAL OF NANOBIOTECHNOLOGY

Enzyme‐Mediated Intracellular Polymerization of AIEgens for Light‐Up Tumor Localization and Theranostics

(2021) Guobin Qi et al.   ADVANCED MATERIALS

Donor/π‐Bridge Manipulation for Constructing a Stable NIR‐II Aggregation‐Induced Emission Luminogen with Balanced Phototheranostic Performance**

(2021) Dingyuan Yan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Mitochondria‐targeted AIEgen Labelled with 18 F for Breast Cancer Cell Imaging and Therapy

(2021) Kaiwu Yu et al.   Chemistry-An Asian Journal

Aggregation-Induced Fluorogens in Bio-Detection, Tumor Imaging, and Therapy: A Review

(2021) Yekkuni L. Balachandran et al.   CCS Chemistry

Molecular Engineered Squaraine Nanoprobe for NIR-II/Photoacoustic Imaging and Photothermal Therapy of Metastatic Breast Cancer

(2020) Defan Yao et al.   ACS Applied Materials & Interfaces

Supramolecular Phthalocyanine Assemblies for Improved Photoacoustic Imaging and Photothermal Therapy

(2020) Xingshu Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Three-Pronged Attack by Homologous Far-Red/NIR AIEgens to Achieve "1+1+1>3" Synergistic Enhanced Photodynamic Therapy

(2020) Wenhan Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

AIEgens Conjugation Improves the Photothermal Efficacy and Near-Infrared Imaging of Heptamethine Cyanine IR-780

(2020) Xiujie Zhao et al.   ACS Applied Materials & Interfaces

Ultrasmall Semiconducting Polymer Dots with Rapid Clearance for Second Near‐Infrared Photoacoustic Imaging and Photothermal Cancer Therapy

(2020) Xiaoju Men et al.   ADVANCED FUNCTIONAL MATERIALS

Constructing Adaptive Photosensitizers via Supramolecular Modification Based on Pillararene Host–Guest Interactions

(2020) Li Shao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Less is more: Silver-AIE core@shell nanoparticles for multimodality cancer imaging and synergistic therapy

(2020) Xuewen He et al.   BIOMATERIALS

An All‐Round Athlete on the Track of Phototheranostics: Subtly Regulating the Balance between Radiative and Nonradiative Decays for Multimodal Imaging‐Guided Synergistic Therapy

(2020) Zhijun Zhang et al.   ADVANCED MATERIALS

Aggregation‐Induced Emission Luminogens Married to 2D Black Phosphorus Nanosheets for Highly Efficient Multimodal Theranostics

(2020) Jiachang Huang et al.   ADVANCED MATERIALS

NIR‐II AIEgens: A Win‐Win Integration towards Bioapplications

(2020) Wenhan Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Clinical development and potential of photothermal and photodynamic therapies for cancer

(2020) Xingshu Li et al.   Nature Reviews Clinical Oncology

AIEgen-coupled upconversion nanoparticles eradicate solid tumors through dual-mode ROS activation

(2020) Duo Mao et al.   Science Advances

Zwitterionic AIEgens: Rational Molecular Design for NIR‐II Fluorescence Imaging‐Guided Synergistic Phototherapy

(2020) Wei Zhu et al.   ADVANCED FUNCTIONAL MATERIALS

HClO‐Activated Fluorescence and Photosensitization from an AIE Nanoprobe for Image‐Guided Bacterial Ablation in Phagocytes

(2020) Min Wu et al.   ADVANCED MATERIALS

Seeking brightness from nature: sustainable carbon dots-based AIEgens with tunable emission wavelength from natural rosin

(2020) Min Ge et al.   CHEMICAL ENGINEERING JOURNAL

Multifunctional FeS2 theranostic nanoparticles for photothermal-enhanced chemodynamic/photodynamic cancer therapy and photoacoustic imaging

(2020) Shuting Xiao et al.   CHEMICAL ENGINEERING JOURNAL

Lesson from Nature: Biomimetic Self-Assembling Phthalocyanines for High-Efficient Photothermal Therapy within the Biological Transparent Window

(2019) Hong-Guang Jin et al.   ACS Applied Materials & Interfaces

Highly efficient photothermal nanoagent achieved by harvesting energy via excited-state intramolecular motion within nanoparticles

(2019) Zheng Zhao et al.   Nature Communications

Molecular Motion in Aggregates: Manipulating TICT for Boosting Photothermal Theranostics

(2019) Shunjie Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Boosting Non-Radiative Decay to Do Useful Work: Development of a Multi-Modality Theranostic System from an AIEgen

(2019) Dong Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

All‐in‐One Phototheranostics: Single Laser Triggers NIR‐II Fluorescence/Photoacoustic Imaging Guided Photothermal/Photodynamic/Chemo Combination Therapy

(2019) Qi Wang et al.   ADVANCED FUNCTIONAL MATERIALS

High‐Resolution 3D NIR‐II Photoacoustic Imaging of Cerebral and Tumor Vasculatures Using Conjugated Polymer Nanoparticles as Contrast Agent

(2019) Bing Guo et al.   ADVANCED MATERIALS

Specific Targeting, Imaging, and Ablation of Tumor-Associated Macrophages by Theranostic Mannose–AIEgen Conjugates

(2019) Xiaoying Gao et al.   ANALYTICAL CHEMISTRY

Multifunctional Two-Photon AIE Luminogens for Highly Mitochondria-Specific Bioimaging and Efficient Photodynamic Therapy

(2019) Weihua Zhuang et al.   ACS Applied Materials & Interfaces

Semiconducting Nanocomposite with AIEgen‐Triggered Enhanced Photoluminescence and Photodegradation for Dual‐Modality Tumor Imaging and Therapy

(2019) Yawen Li et al.   ADVANCED FUNCTIONAL MATERIALS

Sandwich-Structured Upconversion Nanoprobes Coated with a Thin Silica Layer for Mitochondria-Targeted Cooperative Photodynamic Therapy for Solid Malignant Tumors

(2019) Xinyue Song et al.   ANALYTICAL CHEMISTRY

AIEgens in cell-based multiplex fluorescence imaging

(2019) Yabin Zhou et al.   Science China-Chemistry

Mitochondria‐Targeted Polydopamine Nanocomposite with AIE Photosensitizer for Image‐Guided Photodynamic and Photothermal Tumor Ablation

(2019) Yuzhi Chen et al.   Small

Albumin tailoring fluorescence and photothermal conversion effect of near-infrared-II fluorophore with aggregation-induced emission characteristics

(2019) Shuai Gao et al.   Nature Communications

Precise Molecular Engineering of Photosensitizers with Aggregation‐Induced Emission over 800 nm for Photodynamic Therapy

(2019) Wenbo Wu et al.   ADVANCED FUNCTIONAL MATERIALS

Surfactant‐Stripped Micelles for NIR‐II Photoacoustic Imaging through 12 cm of Breast Tissue and Whole Human Breasts

(2019) Upendra Chitgupi et al.   ADVANCED MATERIALS

Rational Design of a Multifunctional Molecular Dye with Single Dose and Laser for Efficiency NIR-II Fluorescence/Photoacoustic Imaging Guided Photothermal Therapy

(2019) Ruiping Zhang et al.   ANALYTICAL CHEMISTRY

Nitric Oxide-Activated “Dual-Key–One-Lock” Nanoprobe for in Vivo Molecular Imaging and High-Specificity Cancer Therapy

(2019) Lili Teng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Supramolecular Nanodiscs Self‐Assembled from Non‐Ionic Heptamethine Cyanine for Imaging‐Guided Cancer Photothermal Therapy

(2019) Xueluer Mu et al.   ADVANCED MATERIALS

Visualization and In Situ Ablation of Intracellular Bacterial Pathogens through Metabolic Labeling

(2019) Fang Hu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Stereotactic Photodynamic Therapy Using a Two‐Photon AIE Photosensitizer

(2019) Xiaojing He et al.   Small

Construction of biocompatible bovine serum albumin nanoparticles composed of nano graphene oxide and AIEgen for dual-mode phototherapy bacteriostatic and bacterial tracking

(2019) Yongxin Zhang et al.   JOURNAL OF NANOBIOTECHNOLOGY

Boosting Fluorescence-Photoacoustic-Raman Properties in One Fluorophore for Precise Cancer Surgery

(2019) Ji Qi et al.   Chem

Nanoaggregate Probe for Breast Cancer Metastasis through Multispectral Optoacoustic Tomography and Aggregation-Induced NIR-I/II Fluorescence Imaging

(2019) Juan Ouyang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Radiolabeling nanomaterials for multimodality imaging: New insights into nuclear medicine and cancer diagnosis

(2019) Jianxian Ge et al.   BIOMATERIALS

Photophysical Tuning of N-Oxide-Based Probes Enables Ratiometric Photoacoustic Imaging of Tumor Hypoxia

(2018) Hailey J. Knox et al.   ACS Chemical Biology

Bright Aggregation-Induced-Emission Dots for Targeted Synergetic NIR-II Fluorescence and NIR-I Photoacoustic Imaging of Orthotopic Brain Tumors

(2018) Zonghai Sheng et al.   ADVANCED MATERIALS

Nanomaterials for Cancer Precision Medicine

(2018) Yilong Wang et al.   ADVANCED MATERIALS

Two-dimensional tellurium nanosheets for photoacoustic imaging-guided photodynamic therapy

(2018) Yan Lin et al.   CHEMICAL COMMUNICATIONS

Light-driven transformable optical agent with adaptive functions for boosting cancer surgery outcomes

(2018) Ji Qi et al.   Nature Communications

2D transition metal dichalcogenide nanosheets for photo/thermo-based tumor imaging and therapy

(2018) Hang Chen et al.   Nanoscale Horizons

Gold Nanorod Photothermal Therapy Alters Cell Junctions and Actin Network in Inhibiting Cancer Cell Collective Migration

(2018) Yue Wu et al.   ACS Nano

Photosensitizers with Aggregation-Induced Emission: Materials and Biomedical Applications

(2018) Fang Hu et al.   ADVANCED MATERIALS

Self-Propelled Nanomotors for Thermomechanically Percolating Cell Membranes

(2018) Mingjun Xuan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Biodegradable hypocrellin derivative nanovesicle as a near-infrared light-driven theranostic for dually photoactive cancer imaging and therapy

(2018) Xiuli Zheng et al.   BIOMATERIALS

Photothermal therapy and photoacoustic imaging via nanotheranostics in fighting cancer

(2018) Yijing Liu et al.   CHEMICAL SOCIETY REVIEWS

Near-Infrared Photoactivatable Nitric Oxide Donors with Integrated Photoacoustic Monitoring

(2018) Effie Y. Zhou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Activatable probes for diagnosing and positioning liver injury and metastatic tumors by multispectral optoacoustic tomography

(2018) Yinglong Wu et al.   Nature Communications

Theranostics based on AIEgens

(2018) Dong Wang et al.   Theranostics

Single-Molecular Near-Infrared-II Theranostic Systems: Ultrastable Aggregation-Induced Emission Nanoparticles for Long-Term Tracing and Efficient Photothermal Therapy

(2018) Nuernisha Alifu et al.   ACS Nano

A Water-Soluble, NIR-Absorbing Quaterrylenediimide Chromophore for Photoacoustic Imaging and Efficient Photothermal Cancer Therapy

(2018) Chang Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Far‐Red/Near‐Infrared Emissive (1,3‐Dimethyl)barbituric Acid‐Based AIEgens for High‐Contrast Detection of Metastatic Tumors in Lung

(2018) Heqi Gao et al.   Chemistry-An Asian Journal

The self-assembly of Cu-In-S quantum dots with aggregation-induced emission into 3D network triggered by cation and its application as a novel metal-enhanced fluorescent nanosensor for detecting Zn (Ⅱ)

(2018) Mingyao Mou et al.   SENSORS AND ACTUATORS B-CHEMICAL

AIE Luminogens for Bioimaging and Theranostics: From Organelles to Animals

(2017) Jun Qian et al.   Chem

Phthalocyanines as medicinal photosensitizers: Developments in the last five years

(2017) Xingshu Li et al.   COORDINATION CHEMISTRY REVIEWS

Recent Development of Chemosensors Based on Cyanine Platforms

(2016) Wen Sun et al.   CHEMICAL REVIEWS

Water-soluble perylenediimides: design concepts and biological applications

(2016) Mengmeng Sun et al.   CHEMICAL SOCIETY REVIEWS

Multifunctional AIEgens for Future Theranostics

(2016) Guangxue Feng et al.   Small

Plasmonic Vesicles of Amphiphilic Nanocrystals: Optically Active Multifunctional Platform for Cancer Diagnosis and Therapy

(2015) Jibin Song et al.   ACCOUNTS OF CHEMICAL RESEARCH

Gold Nanomaterials at Work in Biomedicine

(2015) Xuan Yang et al.   CHEMICAL REVIEWS

Diketopyrrolopyrrole: brilliant red pigment dye-based fluorescent probes and their applications

(2015) Matinder Kaur et al.   CHEMICAL SOCIETY REVIEWS

Combination delivery of Adjudin and Doxorubicin via integrating drug conjugation and nanocarrier approaches for the treatment of drug-resistant cancer cells

(2015) Xu Li et al.   Journal of Materials Chemistry B

Aptamer–conjugated graphene oxide–gold nanocomposites for targeted chemo-photothermal therapy of cancer cells

(2015) Xinhuan Wang et al.   Journal of Materials Chemistry B

Fine-tuning the LSPR response of gold nanorod–polyaniline core–shell nanoparticles with high photothermal efficiency for cancer cell ablation

(2015) Hui Hou et al.   Journal of Materials Chemistry B

Perylene-Diimide-Based Nanoparticles as Highly Efficient Photoacoustic Agents for Deep Brain Tumor Imaging in Living Mice

(2014) Quli Fan et al.   ADVANCED MATERIALS

Noncovalent interaction-assisted polymeric micelles for controlled drug delivery

(2014) Jianxun Ding et al.   CHEMICAL COMMUNICATIONS

AIE macromolecules: syntheses, structures and functionalities

(2014) Rongrong Hu et al.   CHEMICAL SOCIETY REVIEWS

Semiconducting polymer nanoparticles as photoacoustic molecular imaging probes in living mice

(2014) Kanyi Pu et al.   Nature Nanotechnology

Magnetic nanoparticles as contrast agents in the diagnosis and treatment of cancer

(2013) Juan Gallo et al.   CHEMICAL SOCIETY REVIEWS

Multimodal Imaging Guided Photothermal Therapy using Functionalized Graphene Nanosheets Anchored with Magnetic Nanoparticles

(2012) Kai Yang et al.   ADVANCED MATERIALS

Photoacoustic Tomography: In Vivo Imaging from Organelles to Organs

(2012) L. V. Wang et al.   SCIENCE

Aggregation-induced emission

(2011) Yuning Hong et al.   CHEMICAL SOCIETY REVIEWS

Biomedical photoacoustic imaging

(2011) P. Beard   Interface Focus