A novel multi-class classification model for schizophrenia, bipolar disorder and healthy controls using comprehensive transcriptomic data

Molecular Mechanism for the Allosteric Inhibition of the Human Serotonin Transporter by Antidepressant Escitalopram

(2022) Weiwei Xue et al.   ACS Chemical Neuroscience

POSREG: proteomic signature discovered by simultaneously optimizing its reproducibility and generalizability

(2022) Fengcheng Li et al.   BRIEFINGS IN BIOINFORMATICS

PFmulDL: a novel strategy enabling multi-class and multi-label protein function annotation by integrating diverse deep learning methods

(2022) Weiqi Xia et al.   COMPUTERS IN BIOLOGY AND MEDICINE

Association Between Bipolar Disorder or Schizophrenia and Oral Anticoagulation Use in Danish Adults With Incident or Prevalent Atrial Fibrillation

(2021) Morten Fenger-Grøn et al.   JAMA Network Open

A pilot study indicating the dysregulation of the complement and coagulation cascades in treated schizophrenia and bipolar disorder patients

(2021) Elisa Castañeda Santa Cruz et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Optimization of metabolomic data processing using NOREVA

(2021) Jianbo Fu et al.   Nature Protocols

VARIDT 2.0: structural variability of drug transporter

(2021) Tingting Fu et al.   NUCLEIC ACIDS RESEARCH

NOREVA: enhanced normalization and evaluation of time-course and multi-class metabolomic data

(2020) Qingxia Yang et al.   NUCLEIC ACIDS RESEARCH

So you think you can PLS-DA?

(2020) Daniel Ruiz-Perez et al.   BMC BIOINFORMATICS

An innovative metabolomic approach for golden rums classification combining ultra-high performance liquid chromatography-Orbitrap mass spectrometry and chemometric strategies

(2019) José Raul Belmonte Sánchez et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Identification of Pre-symptomatic Gene Signatures That Predict Resilience to Cognitive Decline in the Genetically Diverse AD-BXD Model

(2019) Sarah M. Neuner et al.   Frontiers in Genetics

Proteomic and transcriptomic analysis to unravel the influence of high temperature on banana fruit during postharvest storage

(2019) Taotao Li et al.   FUNCTIONAL & INTEGRATIVE GENOMICS

Identification of the gene signature reflecting schizophrenia’s etiology by constructing artificial intelligence‐based method of enhanced reproducibility

(2019) Qing‐Xia Yang et al.   CNS Neuroscience & Therapeutics

Transcriptome association studies of neuropsychiatric traits in African Americans implicate PRMT7 in schizophrenia

(2019) Peter N. Fiorica et al.   PeerJ

A novel bioinformatics approach to identify the consistently well-performing normalization strategy for current metabolomic studies

(2019) Qingxia Yang et al.   BRIEFINGS IN BIOINFORMATICS

Diurnal rhythms in gene expression in the prefrontal cortex in schizophrenia

(2019) Marianne L. Seney et al.   Nature Communications

Neuropeptides and oligopeptidases in schizophrenia

(2019) Benjamín Rodríguez et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Partial least squares-discriminant analysis (PLS-DA) for classification of high-dimensional (HD) data: a review of contemporary practice strategies and knowledge gaps

(2018) Loong Chuen Lee et al.   ANALYST

Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

(2018) Douglas M. Ruderfer et al.   CELL

Abdominal Vagal Afferents Modulate the Brain Transcriptome and Behaviors Relevant to Schizophrenia

(2018) Melanie Klarer et al.   JOURNAL OF NEUROSCIENCE

Inflammasome signalling in brain function and neurodegenerative disease

(2018) Michael T. Heneka et al.   NATURE REVIEWS NEUROSCIENCE

Inference of cell type content from human brain transcriptomic datasets illuminates the effects of age, manner of death, dissection, and psychiatric diagnosis

(2018) Megan Hastings Hagenauer et al.   PLoS One

Transcriptome-wide isoform-level dysregulation in ASD, schizophrenia, and bipolar disorder

(2018) Michael J. Gandal et al.   SCIENCE

Mapping the Heterogeneous Phenotype of Schizophrenia and Bipolar Disorder Using Normative Models

(2018) Thomas Wolfers et al.   JAMA Psychiatry

Immunomodulatory effects of antipsychotic treatment on gene expression in first-episode psychosis

(2018) Outi Mantere et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Clinical trials, progression-speed differentiating features and swiftness rule of the innovative targets of first-in-class drugs

(2018) Ying Hong Li et al.   BRIEFINGS IN BIOINFORMATICS

Neuronal regulation of type 2 innate lymphoid cells via neuromedin U

(2017) Vânia Cardoso et al.   NATURE

Genetic insights into the neurodevelopmental origins of schizophrenia

(2017) Rebecca Birnbaum et al.   NATURE REVIEWS NEUROSCIENCE

The cell cycle-related genes as biomarkers for schizophrenia

(2016) Satoshi Okazaki et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Evaluation of association of common variants in HTR1A and HTR5A with schizophrenia and executive function

(2016) Fanglin Guan et al.   Scientific Reports

Etiologic, Phenomenologic, and Endophenotypic Overlap of Schizophrenia and Bipolar Disorder

(2015) Godfrey D. Pearlson   Annual Review of Clinical Psychology

Copy Number Variable MicroRNAs in Schizophrenia and Their Neurodevelopmental Gene Targets

(2015) William Warnica et al.   BIOLOGICAL PSYCHIATRY

Neuromedin U: A Multifunctional Neuropeptide with Pleiotropic Roles

(2015) V. G. Martinez et al.   CLINICAL CHEMISTRY

Polygenic risk scores for schizophrenia and bipolar disorder predict creativity

(2015) Robert A Power et al.   NATURE NEUROSCIENCE

Innate immune response is differentially dysregulated between bipolar disease and schizophrenia

(2015) Angelica de Baumont et al.   SCHIZOPHRENIA RESEARCH

Pathway-based analysis for genome-wide association study data of bipolar disorder provides new insights for genetic study

(2015) Suhua Chang et al.   Protein & Cell

STEP Levels Are Unchanged in Pre-Frontal Cortex and Associative Striatum in Post-Mortem Human Brain Samples from Subjects with Schizophrenia, Bipolar Disorder and Major Depressive Disorder

(2015) Thomas A. Lanz et al.   PLoS One

cytoHubba: identifying hub objects and sub-networks from complex interactome

(2014) Chia-Hao Chin et al.   BMC Systems Biology

Programming tools: Adventures with R

(2014) Sylvia Tippmann   NATURE

APOE and APOC1 gene polymorphisms are associated with cognitive impairment progression in Chinese patients with late-onset Alzheimer′s disease

(2014) Wandong Zhang et al.   Neural Regeneration Research

STRING v10: protein–protein interaction networks, integrated over the tree of life

(2014) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Meta-analysis of gene coexpression networks in the post-mortem prefrontal cortex of patients with schizophrenia and unaffected controls

(2013) Meeta Mistry et al.   BMC NEUROSCIENCE

Polygenic dissection of diagnosis and clinical dimensions of bipolar disorder and schizophrenia

(2013) D M Ruderfer et al.   MOLECULAR PSYCHIATRY

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

(2013) S Hong Lee et al.   NATURE GENETICS

Can structural MRI aid in clinical classification? A machine learning study in two independent samples of patients with schizophrenia, bipolar disorder and healthy subjects

(2013) Hugo G. Schnack et al.   NEUROIMAGE

Searching joint association signals in CATIE schizophrenia genome-wide association studies through a refined integrative network approach

(2012) Peilin Jia et al.   BMC GENOMICS

A combined analysis of microarray gene expression studies of the human prefrontal cortex identifies genes implicated in schizophrenia

(2012) Josué Pérez-Santiago et al.   JOURNAL OF PSYCHIATRIC RESEARCH

A Critical Assessment of Feature Selection Methods for Biomarker Discovery in Clinical Proteomics

(2012) Christin Christin et al.   MOLECULAR & CELLULAR PROTEOMICS

Genome-wide expression profiling of schizophrenia using a large combined cohort

(2012) M Mistry et al.   MOLECULAR PSYCHIATRY

LIBSVM

(2012) Chih-Chung Chang et al.   ACM Transactions on Intelligent Systems and Technology

Sparse PLS discriminant analysis: biologically relevant feature selection and graphical displays for multiclass problems

(2011) Kim-Anh Lê Cao et al.   BMC BIOINFORMATICS

Imprinted DLK1-DIO3 region of 14q32 defines a schizophrenia-associated miRNA signature in peripheral blood mononuclear cells

(2011) E Gardiner et al.   MOLECULAR PSYCHIATRY

Abnormal Activity of the MAPK- and cAMP-Associated Signaling Pathways in Frontal Cortical Areas in Postmortem Brain in Schizophrenia

(2011) Adam J Funk et al.   NEUROPSYCHOPHARMACOLOGY

SNP-based analysis of neuroactive ligand–receptor interaction pathways implicates PGE2 as a novel mediator of antipsychotic treatment response: Data from the CATIE study

(2011) Daniel E. Adkins et al.   SCHIZOPHRENIA RESEARCH

Genome-wide association study of major depressive disorder: new results, meta-analysis and lessons learned

(2010) N R Wray et al.   MOLECULAR PSYCHIATRY

Case-control association study of 65 candidate genes revealed a possible association of a SNP of HTR5A to be a factor susceptible to bipolar disease in Bulgarian population

(2009) Adelina Yosifova et al.   JOURNAL OF AFFECTIVE DISORDERS

Common genetic determinants of schizophrenia and bipolar disorder in Swedish families: a population-based study

(2009) Paul Lichtenstein et al.   LANCET

Common polygenic variation contributes to risk of schizophrenia and bipolar disorder

(2009) Shaun M. Purcell et al.   NATURE

Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: the SzGene database

(2008) Nicole C Allen et al.   NATURE GENETICS