The Cytokine Release Syndrome and/or the Proinflammatory Cytokines as Underlying Mechanisms of Downregulation of Drug Metabolism and Drug Transport: A Systematic Review of the Clinical Pharmacokinetics of Victim Drugs of this Drug–Disease Interaction Under Different Clinical Conditions

Clinical Pharmacokinetics of Triazoles in Pediatric Patients

(2021) Didi Bury et al.   CLINICAL PHARMACOKINETICS

Clinically Significant Drug Interactions Between Psychotropic Agents and Repurposed COVID-19 Therapies

(2021) Milo Gatti et al.   CNS DRUGS

The PRISMA 2020 statement: an updated guideline for reporting systematic reviews

(2021) Matthew J Page et al.   BMJ-British Medical Journal

Impact of Interferons and Biological Drug Inhibitors of IL-2 and IL-6 on Small-Molecule Drug Metabolism Through the Cytochrome P450 System

(2021) C. Michael White et al.   ANNALS OF PHARMACOTHERAPY

Impact of Inflammation on Cytochromes P450 Activity in Pediatrics: A Systematic Review

(2021) Camille Lenoir et al.   CLINICAL PHARMACOKINETICS

Tocilizumab in COVID-19: a meta-analysis, trial sequential analysis, and meta-regression of randomized-controlled trials

(2021) Timothy Arthur Chandos Snow et al.   INTENSIVE CARE MEDICINE

Inflammation Suppresses Patients’ Ability to Metabolize Cytochrome P450 Substrate Drugs

(2021) C. Michael White   ANNALS OF PHARMACOTHERAPY

Clinical and Molecular Perspectives on Inflammation‐Mediated Regulation of Drug Metabolism and Transport

(2021) Ann‐Cathrine Dalgård Dunvald et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Influence of Inflammation on Cytochromes P450 Activity in Adults: A Systematic Review of the Literature

(2021) Camille Lenoir et al.   Frontiers in Pharmacology

Around 3% of 1,300 Levels Were Elevated during Infections in a Retrospective Review of 131 Beijing Hospital In-Patients with More than 24,000 Days of Clozapine Treatment

(2020) Can-Jun Ruan et al.   PSYCHOTHERAPY AND PSYCHOSOMATICS

Pharmacokinetics of Lopinavir and Ritonavir in Patients Hospitalized With Coronavirus Disease 2019 (COVID-19)

(2020) Christian Schoergenhofer et al.   ANNALS OF INTERNAL MEDICINE

Evaluating Potential Disease‐Mediated Protein‐Drug Interactions in Patients With Moderate‐to‐Severe Plaque Psoriasis Receiving Subcutaneous Guselkumab

(2020) Yaowei Zhu et al.   CTS-Clinical and Translational Science

Systemic Lupus Erythematosus Activity Affects the Sinusoidal Uptake Transporter OATP1B1 Evaluated by the Pharmacokinetics of Atorvastatin

(2020) Roberta Natália Cestari et al.   CTS-Clinical and Translational Science

Rheumatoid arthritis downregulates the drug transporter OATP1B1: Fluvastatin as a probe

(2020) Juciene Aparecida Caris et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Lopinavir pharmacokinetics in COVID-19 patients

(2020) Matthieu Gregoire et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Comparative Population Pharmacokinetics of Darunavir in SARS-CoV-2 Patients vs. HIV Patients: The Role of Interleukin-6

(2020) Pier Giorgio Cojutti et al.   CLINICAL PHARMACOKINETICS

Optimization of voriconazole therapy for treatment of invasive aspergillosis: Pharmacogenomics and inflammatory status need to be evaluated

(2020) Elodie Gautier‐Veyret et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Impact of Acute Inflammation on Cytochromes P450 Activity Assessed by the Geneva Cocktail

(2020) Camille Lenoir et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Cytokine Storm

(2020) David C. Fajgenbaum et al.   NEW ENGLAND JOURNAL OF MEDICINE

Posaconazole trough concentrations are not influenced by inflammation: a prospective study

(2019) Anne-Grete Märtson et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Simulating the Impact of Elevated Levels of Interleukin-6 on the Pharmacokinetics of Various CYP450 Substrates in Patients with Neuromyelitis Optica or Neuromyelitis Optica Spectrum Disorders in Different Ethnic Populations

(2019) Krishna K. Machavaram et al.   AAPS Journal

Modulation of CYP450 activities in patients with type 2 diabetes

(2019) Sophie Gravel et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Tocilizumab for the treatment of chimeric antigen receptor T cell-induced cytokine release syndrome

(2019) Chelsea Kotch et al.   Expert Review of Clinical Immunology

Altered cytochrome 2E1 and 3A P450‐dependent drug metabolism in advanced ovarian cancer correlates to tumour‐associated inflammation

(2019) Sebastian Trousil et al.   BRITISH JOURNAL OF PHARMACOLOGY

Secukinumab Treatment Does Not Alter the Pharmacokinetics of the Cytochrome P450 3A4 Substrate Midazolam in Patients With Moderate to Severe Psoriasis

(2019) Gerard Bruin et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Effect of tildrakizumab (MK-3222), a high affinity, selective anti-IL23p19 monoclonal antibody, on cytochrome P450 metabolism in subjects with moderate to severe psoriasis

(2018) S. Khalilieh et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Evaluation of Potential Disease-Mediated Drug-Drug Interaction in Patients With Moderate-to-Severe Atopic Dermatitis Receiving Dupilumab

(2018) John D. Davis et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Disease-Associated Changes in Drug Transporters May Impact the Pharmacokinetics and/or Toxicity of Drugs: A White Paper From the International Transporter Consortium

(2018) Raymond Evers et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Disease-Drug Interactions in Inflammatory States via Effects on CYP-Mediated Drug Clearance

(2018) David E. Coutant et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Influence of Inflammation on the Pharmacokinetics of Perampanel

(2018) Yoshiaki Yamamoto et al.   THERAPEUTIC DRUG MONITORING

ASBMT Consensus Grading for Cytokine Release Syndrome and Neurological Toxicity Associated with Immune Effector Cells

(2018) Daniel W Lee et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Significant effect of infection and food intake on sirolimus pharmacokinetics and exposure in pediatric patients with acute lymphoblastic leukemia

(2018) Tomoyuki Mizuno et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Relationship Between the CYP2C19 Phenotype Using the Voriconazole-to-Voriconazole N-Oxide Plasma Concentration Ratio and Demographic and Clinical Characteristics of Japanese Patients With Different CYP2C19 Genotypes

(2017) Takenori Niioka et al.   THERAPEUTIC DRUG MONITORING

Development of a Physiologically Based Pharmacokinetic Model to Predict Disease-Mediated Therapeutic Protein–Drug Interactions: Modulation of Multiple Cytochrome P450 Enzymes by Interleukin-6

(2016) Xiling Jiang et al.   AAPS Journal

Inflammation and Organ Failure Severely Affect Midazolam Clearance in Critically Ill Children

(2016) Nienke J. Vet et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Longitudinal Analysis of the Effect of Inflammation on Voriconazole Trough Concentrations

(2016) M. A. Encalada Ventura et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Therapeutic protein-drug interaction assessment for daclizumab high-yield process in patients with multiple sclerosis using a cocktail approach

(2016) Jonathan Q. Tran et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Disease–Drug Interaction of Sarilumab and Simvastatin in Patients with Rheumatoid Arthritis

(2016) Eun Bong Lee et al.   CLINICAL PHARMACOKINETICS

Voriconazole metabolism is influenced by severe inflammation: a prospective study

(2016) Anette Veringa et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Influence of Inflammation on Voriconazole Metabolism

(2015) M. A. Encalada Ventura et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Impact of inflammation and concomitant glucocorticoid administration on plasma concentration of triazole antifungals in immunocompromised patients

(2015) Takafumi Naito et al.   CLINICA CHIMICA ACTA

Pharmacokinetics, Pharmacodynamics and Pharmacogenomics of Immunosuppressants in Allogeneic Haematopoietic Cell Transplantation: Part I

(2015) Jeannine S. McCune et al.   CLINICAL PHARMACOKINETICS

Evaluation of disease-mediated therapeutic protein-drug interactions between an anti-interleukin-6 monoclonal antibody (sirukumab) and cytochrome P450 activities in a phase 1 study in patients with rheumatoid arthritis using a cocktail approach

(2015) Yanli Zhuang et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Retrospective Pilot Study for Analysis of Antidepressant Serum Concentrations of Citalopram and Venlafaxine during Inflammation

(2015) G. Hefner et al.   PHARMACOPSYCHIATRY

Inflammation and psychotropic drugs: the relationship between C-reactive protein and antipsychotic drug levels

(2015) Gudrun Hefner et al.   PSYCHOPHARMACOLOGY

Inflammation Is Associated with Voriconazole Trough Concentrations

(2014) Marjolijn J. P. van Wanrooy et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A Physiologically Based Pharmacokinetic Modeling Approach to Predict Disease–Drug Interactions: Suppression of CYP3A by IL-6

(2013) K K Machavaram et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Effects of Interleukin 1β (IL-1β) and IL-1β/Interleukin 6 (IL-6) Combinations on Drug Metabolizing Enzymes in Human Hepatocyte Culture

(2012) Leslie J. Dickmann et al.   CURRENT DRUG METABOLISM

Disease–Drug–Drug Interaction Involving Tocilizumab and Simvastatin in Patients With Rheumatoid Arthritis

(2011) C Schmitt et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

The effect of inflammation on drug metabolism: a focus on pediatrics

(2011) Nienke J. Vet et al.   DRUG DISCOVERY TODAY

Effects of Interleukin-6 (IL-6) and an Anti-IL-6 Monoclonal Antibody on Drug-Metabolizing Enzymes in Human Hepatocyte Culture

(2011) L. J. Dickmann et al.   DRUG METABOLISM AND DISPOSITION

Inflammation: Planning for a Source of Pharmacokinetic/Pharmacodynamic Variability in Translational Studies

(2010) V D Schmith et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Pharmacokinetics of lidocaine and its metabolite in peridural anesthesia administered to pregnant women with gestational diabetes mellitus

(2008) Elaine Christine Dantas Moisés et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY