Melatonin prevents diabetes‐induced nephropathy by modulating the AMPK/SIRT1 axis: Focus on autophagy and mitochondrial dysfunction

FeTMPyP a peroxynitrite decomposition catalyst ameliorated functional and behavioral deficits in chronic constriction injury induced neuropathic pain in rats

(2022) Prashanth Komirishetty et al.   FREE RADICAL RESEARCH

Renoprotective potential of myo‐inositol on diabetic kidney disease: Focus on the role of the PINK1/Parkin pathway and mitophagy receptors

(2022) Bhoomika Sherkhane et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Empagliflozin Regulates the AdipoR1/p-AMPK/p-ACC Pathway to Alleviate Lipid Deposition in Diabetic Nephropathy

(2021) Zhiqin Zhang et al.   Diabetes Metabolic Syndrome and Obesity-Targets and Therapy

Efficacy and safety of finerenone in patients with chronic kidney disease and type 2 diabetes by GLP‐1RA treatment: A subgroup analysis from the FIDELIO‐DKD trial

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Probucol attenuates NF-κB/NLRP3 signalling and augments Nrf-2 mediated antioxidant defence in nerve injury induced neuropathic pain

(2021) Kalyani Derangula et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Telmisartan attenuates diabetic nephropathy by mitigating oxidative stress and inflammation, and upregulating Nrf2/HO-1 signaling in diabetic rats

(2021) Samar A. Antar et al.   LIFE SCIENCES

Folic acid and melatonin mitigate diabetic nephropathy in rats via inhibition of oxidative stress

(2020) Hossam Ebaid et al.   Nutrition & Metabolism

The Role of PGC-1α and Mitochondrial Biogenesis in Kidney Diseases

(2020) Miguel Fontecha-Barriuso et al.   Biomolecules

An updated overview of diabetic nephropathy: Diagnosis, prognosis, treatment goals and latest guidelines

(2020) Nicholas M. Selby et al.   DIABETES OBESITY & METABOLISM

SirT3 activates AMPK-related mitochondrial biogenesis and ameliorates sepsis-induced myocardial injury

(2020) Ting Xin et al.   Aging-US

SIRT1 Activation by Polydatin Alleviates Oxidative Damage and Elevates Mitochondrial Biogenesis in Experimental Diabetic Neuropathy

(2020) Preethi Bheereddy et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

p53/microRNA-214/ULK1 axis impairs renal tubular autophagy in diabetic kidney disease

(2020) Zhengwei Ma et al.   JOURNAL OF CLINICAL INVESTIGATION

Genetic or Pharmacologic Nrf2 Activation Increases Proteinuria in Chronic Kidney Disease in Mice

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Reducing NADPH Synthesis Counteracts Diabetic Nephropathy through Restoration of AMPK Activity in Type 1 Diabetic Rats

(2020) Xiao Wei et al.   Cell Reports

AMPK signalling: Implications for podocyte biology in diabetic nephropathy

(2019) Maria Szrejder et al.   BIOLOGY OF THE CELL

Obacunone attenuates high glucose-induced oxidative damage in NRK-52E cells by inhibiting the activity of GSK-3β

(2019) Jie Zhou et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Hierarchical activation of compartmentalized pools of AMPK depends on severity of nutrient or energy stress

(2019) Yue Zong et al.   CELL RESEARCH

WITHDRAWN: Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: results from the International Diabetes Federation Diabetes Atlas, 9th edition

(2019) Pouya Saeedi et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Metformin alleviates oxidative stress and enhances autophagy in diabetic kidney disease via AMPK/SIRT1-FoxO1 pathway

(2019) Huiwen Ren et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

SIRT1 as a Therapeutic Target in Diabetic Complications

(2018) Justyna Strycharz et al.   CURRENT MEDICINAL CHEMISTRY

Sirt1: A Guardian of the Development of Diabetic Retinopathy

(2018) Manish Mishra et al.   DIABETES

Diabetic nephropathy: Is there a role for oxidative stress?

(2018) Manpreet K. Sagoo et al.   FREE RADICAL BIOLOGY AND MEDICINE

Sirtuins in Renal Health and Disease

(2018) Marina Morigi et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Targeting AMPK in Diabetes and Diabetic Complications: Energy homeostasis, Autophagy and Mitochondrial health

(2018) Y. V. Madhavi et al.   CURRENT MEDICINAL CHEMISTRY

Circadian rhythm and melatonin in the treatment of depression

(2018) Senthil Kumaran Satyanarayanan et al.   CURRENT PHARMACEUTICAL DESIGN

Melatonin attenuates myocardial ischemia reperfusion injury via improving mitochondrial fusion/mitophagy and activating the AMPK-OPA1 signaling pathways

(2018) Ying Zhang et al.   JOURNAL OF PINEAL RESEARCH

Salidroside stimulates the Sirt1/PGC-1α axis and ameliorates diabetic nephropathy in mice

(2018) Haiyan Xue et al.   PHYTOMEDICINE

Regulation of selective autophagy: the p62/SQSTM1 paradigm

(2017) Trond Lamark et al.   Essays in Biochemistry

High glucose stimulates cell proliferation and Collagen IV production in rat mesangial cells through inhibiting AMPK-KATP signaling

(2017) Bei Zhang et al.   INTERNATIONAL UROLOGY AND NEPHROLOGY

Isoliquiritigenin reduces oxidative damage and alleviates mitochondrial impairment by SIRT1 activation in experimental diabetic neuropathy

(2017) Veera Ganesh Yerra et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Adiponectin attenuates high glucose-induced apoptosis through the AMPK/p38 MAPK signaling pathway in NRK-52E cells

(2017) Yuanyuan Wang et al.   PLoS One

Ror2 signaling regulates Golgi structure and transport through IFT20 for tumor invasiveness

(2017) Michiru Nishita et al.   Scientific Reports

Atrasentan Reduces Albuminuria by Restoring the Glomerular Endothelial Glycocalyx Barrier in Diabetic Nephropathy

(2016) Margien G.S. Boels et al.   DIABETES

Lipid droplet–mediated ER homeostasis regulates autophagy and cell survival during starvation

(2016) Ariadna P. Velázquez et al.   JOURNAL OF CELL BIOLOGY

Melatonin as an antioxidant: under promises but over delivers

(2016) Russel J. Reiter et al.   JOURNAL OF PINEAL RESEARCH

Selenium levels and Glutathione peroxidase activity in the plasma of patients with type II diabetes mellitus

(2016) Raquel González de Vega et al.   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

Adenosine Monophosphate-Activated Protein Kinase Abates Hyperglycaemia-Induced Neuronal Injury in Experimental Models of Diabetic Neuropathy: Effects on Mitochondrial Biogenesis, Autophagy and Neuroinflammation

(2016) Veera Ganesh Yerra et al.   MOLECULAR NEUROBIOLOGY

Valproate attenuates the proteinuria, podocyte and renal injury by facilitating autophagy and inactivation of NF-κB/iNOS signaling in diabetic rat

(2015) Sabbir Khan et al.   BIOCHIMIE

Impaired Podocyte Autophagy Exacerbates Proteinuria in Diabetic Nephropathy

(2015) Atsuko Tagawa et al.   DIABETES

AMPK-Dependent Phosphorylation of GAPDH Triggers Sirt1 Activation and Is Necessary for Autophagy upon Glucose Starvation

(2015) Chunmei Chang et al.   MOLECULAR CELL

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(2015) Alejo Efeyan et al.   NATURE

Glomerular and Tubular Function in the Diabetic Kidney

(2014) Roland C. Blantz et al.   ADVANCES IN CHRONIC KIDNEY DISEASE

Sequential Actions of SIRT1-RELB-SIRT3 Coordinate Nuclear-Mitochondrial Communication during Immunometabolic Adaptation to Acute Inflammation and Sepsis

(2014) Tie Fu Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Renal histologic changes and the outcome in patients with diabetic nephropathy

(2014) Y. An et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Metabolomics Reveals Signature of Mitochondrial Dysfunction in Diabetic Kidney Disease

(2013) K. Sharma et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

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(2013) Daniel Fineberg et al.   Nature Reviews Endocrinology

Autophagy: Emerging Therapeutic Target for Diabetic Nephropathy

(2013) Shinji Kume et al.   SEMINARS IN NEPHROLOGY

The Role of Autophagy in the Pathogenesis of Diabetic Nephropathy

(2013) Kosuke Yamahara et al.   Journal of Diabetes Research

Potential therapeutic effects of the simultaneous targeting of the Nrf2 and NF-κB pathways in diabetic neuropathy

(2013) Veera Ganesh Yerra et al.   Redox Biology

Canonical and non-canonical autophagy: variations on a common theme of self-eating?

(2011) Patrice Codogno et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Oxidative Stress and Diabetic Complications

(2010) Ferdinando Giacco et al.   CIRCULATION RESEARCH

Autophagy: cellular and molecular mechanisms

(2010) Danielle Glick et al.   JOURNAL OF PATHOLOGY

The pathogenesis of diabetic nephropathy

(2008) Suma Dronavalli et al.   Nature clinical practice. Endocrinology & metabolism