Etomoxir, a carnitine palmitoyltransferase 1 inhibitor, combined with temozolomide reduces stemness and invasiveness in patient-derived glioblastoma tumorspheres
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Title
Etomoxir, a carnitine palmitoyltransferase 1 inhibitor, combined with temozolomide reduces stemness and invasiveness in patient-derived glioblastoma tumorspheres
Authors
Keywords
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Journal
Cancer Cell International
Volume 22, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2022-10-11
DOI
10.1186/s12935-022-02731-7
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Note: Only part of the references are listed.- Fatty acid β-oxidation promotes breast cancer stemness and metastasis via the miRNA-328-3p-CPT1A pathway
- (2021) Feng Zeng et al. CANCER GENE THERAPY
- The 2021 WHO Classification of Tumors of the Central Nervous System: a summary
- (2021) David N Louis et al. NEURO-ONCOLOGY
- A novel biguanide (IM1761065) inhibits bioenergetics of glioblastoma tumorspheres
- (2021) Tae Hoon Roh et al. JOURNAL OF NEURO-ONCOLOGY
- High ATP Production Fuels Cancer Drug Resistance and Metastasis: Implications for Mitochondrial ATP Depletion Therapy
- (2021) Marco Fiorillo et al. Frontiers in Oncology
- Enhanced fatty acid oxidation provides glioblastoma cells metabolic plasticity to accommodate to its dynamic nutrient microenvironment
- (2020) Shiva Kant et al. Cell Death & Disease
- Combined effects of niclosamide and temozolomide against human glioblastoma tumorspheres
- (2020) Hyeong-Cheol Oh et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- Single-cell RNA-seq reveals that glioblastoma recapitulates a normal neurodevelopmental hierarchy
- (2020) Charles P. Couturier et al. Nature Communications
- The Role of Mitochondrial Fat Oxidation in Cancer Cell Proliferation and Survival
- (2020) Matheus Pinto De Oliveira et al. Cells
- L-Carnitine Mediated Tumor Cell Protection and Poor Patient Survival Associated with OCTN2 Overexpression in Glioblastoma Multiforme
- (2019) Matthias A. Fink et al. CLINICAL CANCER RESEARCH
- Combined treatment with 2′-hydroxycinnamaldehyde and temozolomide suppresses glioblastoma tumorspheres by decreasing stemness and invasiveness
- (2019) Hyewon Jeong et al. JOURNAL OF NEURO-ONCOLOGY
- 20(S)-Protopanaxadiol Inhibits Angiotensin II-Induced Epithelial- Mesenchymal Transition by Downregulating SIRT1
- (2019) Yuchen Wang et al. Frontiers in Pharmacology
- Fatty acid oxidation inhibitor etomoxir suppresses tumor progression and induces cell cycle arrest via PPARγ-mediated pathway in bladder cancer
- (2019) Songtao Cheng et al. CLINICAL SCIENCE
- JAK/STAT3-Regulated Fatty Acid β-Oxidation Is Critical for Breast Cancer Stem Cell Self-Renewal and Chemoresistance
- (2018) Tianyi Wang et al. Cell Metabolism
- CPT1A-mediated fatty acid oxidation promotes colorectal cancer cell metastasis by inhibiting anoikis
- (2018) Ying-nan Wang et al. ONCOGENE
- Activation of G protein-coupled estrogen receptor signaling inhibits melanoma and improves response to immune checkpoint blockade
- (2018) Christopher A Natale et al. eLife
- Human glioblastoma arises from subventricular zone cells with low-level driver mutations
- (2018) Joo Ho Lee et al. NATURE
- Metabolic shifts in residual breast cancer drive tumor recurrence
- (2017) Kristina M. Havas et al. JOURNAL OF CLINICAL INVESTIGATION
- Long-term outcomes of concomitant chemoradiotherapy with temozolomide for newly diagnosed glioblastoma patients
- (2017) Tae Hoon Roh et al. MEDICINE
- The clinical value of patient-derived glioblastoma tumorspheres in predicting treatment response
- (2017) Quintino Giorgio D’Alessandris et al. NEURO-ONCOLOGY
- Regulation of bioenergetics through dual inhibition of aldehyde dehydrogenase and mitochondrial complex I suppresses glioblastoma tumorspheres
- (2017) Junseong Park et al. NEURO-ONCOLOGY
- Smad inhibitor induces CSC differentiation for effective chemosensitization in cyclin D1- and TGF-β/Smad-regulated liver cancer stem cell-like cells
- (2017) Wei Xia et al. Oncotarget
- Hallmarks of cancer stem cell metabolism
- (2016) Patricia Sancho et al. BRITISH JOURNAL OF CANCER
- Inhibition of fatty acid oxidation as a therapy for MYC-overexpressing triple-negative breast cancer
- (2016) Roman Camarda et al. NATURE MEDICINE
- Fatty acid oxidation is required for the respiration and proliferation of malignant glioma cells
- (2016) Hua Lin et al. NEURO-ONCOLOGY
- The Warburg Effect: How Does it Benefit Cancer Cells?
- (2016) Maria V. Liberti et al. TRENDS IN BIOCHEMICAL SCIENCES
- Inhibiting stemness and invasive properties of glioblastoma tumorsphere by combined treatment with temozolomide and a newly designed biguanide (HL156A)
- (2016) Junjeong Choi et al. Oncotarget
- Targeting ALDH1A1 by disulfiram/copper complex inhibits non-small cell lung cancer recurrence driven by ALDH-positive cancer stem cells
- (2016) Xinwei Liu et al. Oncotarget
- Fundamentals of cancer metabolism
- (2016) R. J. DeBerardinis et al. Science Advances
- The DNA damage/repair cascade in glioblastoma cell lines after chemotherapeutic agent treatment
- (2015) LAURA ANNOVAZZI et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Metabolic pathways promoting cancer cell survival and growth
- (2015) Lindsey K. Boroughs et al. NATURE CELL BIOLOGY
- Lipid Catabolism via CPT1 as a Therapeutic Target for Prostate Cancer
- (2014) I. R. Schlaepfer et al. MOLECULAR CANCER THERAPEUTICS
- Metabolic targets for cancer therapy
- (2013) Lorenzo Galluzzi et al. NATURE REVIEWS DRUG DISCOVERY
- Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate
- (2012) Patrick S. Ward et al. CANCER CELL
- Isolation of glioma cancer stem cells in relation to histological grades in glioma specimens
- (2012) Byung Ho Kong et al. CHILDS NERVOUS SYSTEM
- Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks
- (2012) Cole Trapnell et al. Nature Protocols
- Ensembl 2013
- (2012) Paul Flicek et al. NUCLEIC ACIDS RESEARCH
- Inhibition of fatty acid oxidation by etomoxir impairs NADPH production and increases reactive oxygen species resulting in ATP depletion and cell death in human glioblastoma cells
- (2010) Lisa S. Pike et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Pharmacologic inhibition of fatty acid oxidation sensitizes human leukemia cells to apoptosis induction
- (2009) Ismael Samudio et al. JOURNAL OF CLINICAL INVESTIGATION
- Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
- (2009) M. G. Vander Heiden et al. SCIENCE
- Minireview: Adenosine 5′-Monophosphate-Activated Protein Kinase Regulation of Fatty Acid Oxidation in Skeletal Muscle
- (2008) Megan E. Osler et al. ENDOCRINOLOGY
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