20(S)-Protopanaxadiol Inhibits Angiotensin II-Induced Epithelial- Mesenchymal Transition by Downregulating SIRT1

The role of angiotensin II in cancer metastasis: Potential of renin-angiotensin system blockade as a treatment for cancer metastasis

(2018) Shin Ishikane et al.   BIOCHEMICAL PHARMACOLOGY

Cancer statistics, 2018

(2018) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Ginsenoside Rg3 sensitizes hypoxic lung cancer cells to cisplatin via blocking of NF-κB mediated epithelial–mesenchymal transition and stemness

(2018) Jingjing Wang et al.   CANCER LETTERS

20(S)-protopanaxadiol (PPD) alleviates scopolamine-induced memory impairment via regulation of cholinergic and antioxidant systems, and expression of Egr-1, c-Fos and c-Jun in mice

(2018) Cong Lu et al.   CHEMICO-BIOLOGICAL INTERACTIONS

20(S)-Protopanaxadiol-Induced Apoptosis in MCF-7 Breast Cancer Cell Line through the Inhibition of PI3K/AKT/mTOR Signaling Pathway

(2018) Hong Zhang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Ginsenoside Derivative 20(S )-Protopanaxadiol Inhibits Solar Ultraviolet Light-Induced Matrix Metalloproteinase-1 Expression

(2017) Seungmin Han et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Ginsenoside Rg3 induces ginsenoside Rb1-comparable cardioprotective effects independent of reducing blood pressure in spontaneously hypertensive rats

(2017) Yichuan Jiang et al.   Experimental and Therapeutic Medicine

Prognostic and clinicopathological significance of SIRT1 expression in NSCLC: a meta-analysis

(2017) Yifei Chen et al.   Oncotarget

Cancer statistics in China, 2015

(2016) Wanqing Chen et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Daxx inhibits hypoxia-induced lung cancer cell metastasis by suppressing the HIF-1α/HDAC1/Slug axis

(2016) Ching-Wen Lin et al.   Nature Communications

Celecoxib and sulindac inhibit TGF-β1-induced epithelial-mesenchymal transition and suppress lung cancer migration and invasion via downregulation of sirtuin 1

(2016) Byong-Ki Cha et al.   Oncotarget

Diverse Roles of SIRT1 in Cancer Biology and Lipid Metabolism

(2015) Glenn Simmons et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Ginsenoside Rg3 inhibits epithelial-mesenchymal transition (EMT) and invasion of lung cancer by down-regulating FUT4

(2015) Lili Tian et al.   Oncotarget

Overexpression of SIRT1 promotes metastasis through epithelial-mesenchymal transition in hepatocellular carcinoma

(2015) Chong Hao et al.   BMC CANCER

Blockade of the renin–angiotensin system inhibits growth of colorectal cancer liver metastases in the regenerating liver

(2014) Shir Lin Koh et al.   CLINICAL & EXPERIMENTAL METASTASIS

Ang II-AT1R Increases Cell Migration Through PI3K/AKT and NF-κB Pathways in Breast Cancer

(2014) Yanbin Zhao et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Widespread FRA1-Dependent Control of Mesenchymal Transdifferentiation Programs in Colorectal Cancer Cells

(2014) Jeannine Diesch et al.   PLoS One

20(S)-Protopanaxadiol Triggers Mitochondrial-Mediated Apoptosis in Human Lung Adenocarcinoma A549 Cells via Inhibiting the PI3K/Akt Signaling Pathway

(2013) Yun-Long Zhang et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

MiR-204 down regulates SIRT1 and reverts SIRT1-induced epithelial-mesenchymal transition, anoikis resistance and invasion in gastric cancer cells

(2013) Lihua Zhang et al.   BMC CANCER

Expression of SIRT1 and cortactin is associated with progression of non-small cell lung cancer

(2013) Sang Jae Noh et al.   PATHOLOGY RESEARCH AND PRACTICE

Epithelial–mesenchymal transition in lung development and disease: does it exist and is it important?

(2013) Domokos Bartis et al.   THORAX

Angiotensin II type 1 receptor antagonists inhibit cell proliferation and angiogenesis in breast cancer

(2012) Xuesong Chen et al.   CANCER LETTERS

Angiotensin II enhances epithelial-to-mesenchymal transition through the interaction between activated hepatic stellate cells and the stromal cell-derived factor-1/CXCR4 axis in intrahepatic cholangiocarcinoma

(2012) KOICHI OKAMOTO et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Loss of SIRT1 histone deacetylase expression associates with tumour progression in colorectal adenocarcinoma

(2012) Si-Hyong Jang et al.   JOURNAL OF CLINICAL PATHOLOGY

Angiotensin II Facilitates Breast Cancer Cell Migration and Metastasis

(2012) Sylvie Rodrigues-Ferreira et al.   PLoS One

Chemical Diversity of Panax ginseng, Panax quinquifolium, and Panax notoginseng

(2012) Dong-Hyun Kim   Journal of Ginseng Research

TGF /TNF -Mediated Epithelial-Mesenchymal Transition Generates Breast Cancer Stem Cells with a Claudin-Low Phenotype

(2011) M. K. Asiedu et al.   CANCER RESEARCH

Angiotensin Peptides and Lung Cancer

(2011) P. E. Gallagher et al.   CURRENT CANCER DRUG TARGETS

IL-6 Promotes Head and Neck Tumor Metastasis by Inducing Epithelial-Mesenchymal Transition via the JAK-STAT3-SNAIL Signaling Pathway

(2011) A. Yadav et al.   MOLECULAR CANCER RESEARCH

Overexpression of ACE2 produces antitumor effects via inhibition of angiogenesis and tumor cell invasion in vivo and in vitro

(2011) Huanying Wan   ONCOLOGY REPORTS

Captopril as a Potential Inhibitor of Lung Tumor Growth and Metastasis

(2009) Samir Attoub et al.   Annals of the New York Academy of Sciences

In Vitro and in Vivo Anticancer Effects of American Ginseng Berry: Exploring Representative Compounds

(2009) Jing-Tian Xie et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Devil and angel in the renin–angiotensin system: ACE–angiotensin II–AT1 receptor axis vs. ACE2–angiotensin-(1–7)–Mas receptor axis

(2009) Masaru Iwai et al.   HYPERTENSION RESEARCH

Biomarkers for epithelial-mesenchymal transitions

(2009) Michael Zeisberg et al.   JOURNAL OF CLINICAL INVESTIGATION

SirT1-null mice develop tumors at normal rates but are poorly protected by resveratrol

(2009) G Boily et al.   ONCOGENE

Experimental therapy of prostate cancer with novel natural product anti-cancer ginsenosides

(2008) Wei Wang et al.   PROSTATE