The clinical application of mesenchymal stromal cells in hematopoietic stem cell transplantation

Quantitative Magnetic Particle Imaging Monitors the Transplantation, Biodistribution, and Clearance of Stem Cells In Vivo

(2016) Bo Zheng et al.   Theranostics

Immunomodulation Effects of Mesenchymal Stromal Cells on Acute Graft-versus-Host Disease after Hematopoietic Stem Cell Transplantation

(2015) Ke Zhao et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Characterization of bone marrow mesenchymal stromal cells in aplastic anaemia

(2015) Edita Hamzic et al.   BRITISH JOURNAL OF HAEMATOLOGY

Intravenous infusion of allogeneic mesenchymal stromal cells in refractory or relapsed aplastic anemia

(2015) Diego V. Clé et al.   CYTOTHERAPY

Umbilical Cord Mesenchymal Stromal Cell With Autologous Bone Marrow Cell Transplantation in Established Type 1 Diabetes: A Pilot Randomized Controlled Open-Label Clinical Study to Assess Safety and Impact on Insulin Secretion

(2015) Jinquan Cai et al.   DIABETES CARE

Clinical grade expansion of MSCs

(2015) C. Capelli et al.   IMMUNOLOGY LETTERS

Unrelated cord blood transplantation for adult patients with acute myeloid leukemia: higher incidence of acute graft-versus-host disease and lower survival in male patients transplanted with female unrelated cord blood—a report from Eurocord, the Acute Leukemia Working Party, and the Cord Blood Committee of the Cellular Therapy and Immunobiology Working Party of the European Group for Blood and Marrow Transplantation

(2015) Frédéric Baron et al.   Journal of Hematology & Oncology

Clinical significance of high-dose cytarabine added to cyclophosphamide/total-body irradiation in bone marrow or peripheral blood stem cell transplantation for myeloid malignancy

(2015) Yasuyuki Arai et al.   Journal of Hematology & Oncology

Non-myeloablative allogeneic hematopoietic cell transplantation following fludarabine plus 2 Gy TBI or ATG plus 8 Gy TLI: a phase II randomized study from the Belgian Hematological Society

(2015) Frédéric Baron et al.   Journal of Hematology & Oncology

Donor-specific anti-human leukocyte antigen antibodies were associated with primary graft failure after unmanipulated haploidentical blood and marrow transplantation: a prospective study with randomly assigned training and validation sets

(2015) Ying-Jun Chang et al.   Journal of Hematology & Oncology

Favorable outcome of haploidentical hematopoietic stem cell transplantation in Philadelphia chromosome-positive acute lymphoblastic leukemia: a multicenter study in Southwest China

(2015) Li Gao et al.   Journal of Hematology & Oncology

Coexpression of gene Oct4 and Nanog initiates stem cell characteristics in hepatocellular carcinoma and promotes epithelial-mesenchymal transition through activation of Stat3/Snail signaling

(2015) Xin Yin et al.   Journal of Hematology & Oncology

Biomarker profiling of steroid-resistant acute GVHD in patients after infusion of mesenchymal stromal cells

(2015) L C J te Boome et al.   LEUKEMIA

Targeted mutagenesis of zebrafish antithrombin III triggers disseminated intravascular coagulation and thrombosis, revealing insight into function

(2014) Y. Liu et al.   BLOOD

Leptin-Receptor-Expressing Mesenchymal Stromal Cells Represent the Main Source of Bone Formed by Adult Bone Marrow

(2014) Bo O. Zhou et al.   Cell Stem Cell

Post-transcriptional regulatory network of epithelial-to-mesenchymal and mesenchymal-to-epithelial transitions

(2014) Fei Guo et al.   Journal of Hematology & Oncology

Advances in understanding the cell types and approaches used for generating induced pluripotent stem cells

(2014) Jun Li et al.   Journal of Hematology & Oncology

The roles of mesenchymal stem cells in tumor inflammatory microenvironment

(2014) Zhao Sun et al.   Journal of Hematology & Oncology

Mesenchymal stromal cells infusions improve refractory chronic graft versus host disease through an increase of CD5+ regulatory B cells producing interleukin 10

(2014) Y Peng et al.   LEUKEMIA

Alteration of Naïve and Memory B-Cell Subset in Chronic Graft-Versus-Host Disease Patients After Treatment With Mesenchymal Stromal Cells

(2014) Yanwen Peng et al.   Stem Cells Translational Medicine

Cotransplantation of haploidentical hematopoietic and umbilical cord mesenchymal stem cells with a myeloablative regimen for refractory/relapsed hematologic malignancy

(2013) Yamei Wu et al.   ANNALS OF HEMATOLOGY

Mesenchymal Stem Cells versus Mesenchymal Stem Cells Combined with Cord Blood for Engraftment Failure after Autologous Hematopoietic Stem Cell Transplantation: A Pilot Prospective, Open-Label, Randomized Trial

(2013) Yi-Ying Xiong et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Allogeneic Human Mesenchymal Stem Cell Therapy (Remestemcel-L, Prochymal) as a Rescue Agent for Severe Refractory Acute Graft-versus-Host Disease in Pediatric Patients

(2013) Joanne Kurtzberg et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Co-transplantation of third-party umbilical cord blood-derived MSCs promotes engraftment in children undergoing unrelated umbilical cord blood transplantation

(2013) S H Lee et al.   BONE MARROW TRANSPLANTATION

Mesenchymal Stromal Cells: Sensors and Switchers of Inflammation

(2013) Maria Ester Bernardo et al.   Cell Stem Cell

Improvement in Poor Graft Function after Allogeneic Hematopoietic Stem Cell Transplantation upon Administration of Mesenchymal Stem Cells from Third-Party Donors: A Pilot Prospective Study

(2013) Xiaodan Liu et al.   CELL TRANSPLANTATION

Efficacy and safety of mesenchymal stromal cell treatment from related donors for patients with refractory aplastic anemia

(2013) Yang Xiao et al.   CYTOTHERAPY

The mesenchymal stromal cells dilemma—does a negative phase III trial of random donor mesenchymal stromal cells in steroid-resistant graft-versus-host disease represent a death knell or a bump in the road?

(2013) Jacques Galipeau   CYTOTHERAPY

ST2 as a Marker for Risk of Therapy-Resistant Graft-versus-Host Disease and Death

(2013) Mark T. Vander Lugt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Emerging roles for multipotent, bone marrow-derived stromal cells in host defense

(2012) J. J. Auletta et al.   BLOOD

Treatment with mesenchymal stromal cells is a risk factor for pneumonia-related death after allogeneic hematopoietic stem cell transplantation

(2012) Ulrica Forslöw et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Treatment of severe acute graft-versus-host disease with mesenchymal stromal cells: a comparison with non-MSC treated patients

(2012) Mats Remberger et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

Clinical applications of mesenchymal stem cells

(2012) Shihua Wang et al.   Journal of Hematology & Oncology

Mesenchymal Stromal Cells Do Not Increase the Risk of Viral Reactivation Nor the Severity of Viral Events in Recipients of Allogeneic Stem Cell Transplantation

(2012) Giovanna Lucchini et al.   Stem Cells International

Immunomodulatory Effect of Mesenchymal Stem Cells on B Cells

(2012) Marcella Franquesa et al.   Frontiers in Immunology

Comparative analysis of risk factors for acute graft-versus-host disease and for chronic graft-versus-host disease according to National Institutes of Health consensus criteria

(2011) M. E. D. Flowers et al.   BLOOD

CD146 expression on primary nonhematopoietic bone marrow stem cells is correlated with in situ localization

(2011) A. Tormin et al.   BLOOD

CM-DiI Labeled Mesenchymal stem cells homed to thymus inducing immune recovery of mice after haploidentical bone marrow transplantation

(2011) Kai-xun Hu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Human but not murine multipotent mesenchymal stromal cells exhibit broad-spectrum antimicrobial effector function mediated by indoleamine 2,3-dioxygenase

(2011) R Meisel et al.   LEUKEMIA

Generation of Human Adult Mesenchymal Stromal/Stem Cells Expressing Defined Xenogenic Vascular Endothelial Growth Factor Levels by Optimized Transduction and Flow Cytometry Purification

(2011) Uta Helmrich et al.   TISSUE ENGINEERING PART C-METHODS

Multipotent Mesenchymal Stromal Cells for the Prophylaxis of Acute Graft-versus-Host Disease—A Phase II Study

(2011) Larisa A. Kuzmina et al.   Stem Cells International

Mesenchymal Stem Cells Reduce Inflammation while Enhancing Bacterial Clearance and Improving Survival in Sepsis

(2010) Shirley H. J. Mei et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Cotransplantation of Mesenchymal Stem Cells Might Prevent Death from Graft-versus-Host Disease (GVHD) without Abrogating Graft-versus-Tumor Effects after HLA-Mismatched Allogeneic Transplantation following Nonmyeloablative Conditioning

(2010) Frédéric Baron et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Platelet-lysate-Expanded Mesenchymal Stromal Cells as a Salvage Therapy for Severe Resistant Graft-versus-Host Disease in a Pediatric Population

(2010) Giovanna Lucchini et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Mesenchymal stem cell as salvage treatment for refractory chronic GVHD

(2010) J Y Weng et al.   BONE MARROW TRANSPLANTATION

Co-infusion of ex vivo-expanded, parental MSCs prevents life-threatening acute GVHD, but does not reduce the risk of graft failure in pediatric patients undergoing allogeneic umbilical cord blood transplantation

(2010) M E Bernardo et al.   BONE MARROW TRANSPLANTATION

Bioimaging for the monitoring of thein vivodistribution of infused mesenchymal stem cells in a mouse model of the graft-versus-host reaction

(2010) Sun‑Young Joo et al.   CELL BIOLOGY INTERNATIONAL

Mesenchymal Stromal Cells: Facilitators of Successful Transplantation?

(2010) Karen English et al.   Cell Stem Cell

Differentiation of human adipose-derived stem cells into beating cardiomyocytes

(2010) Yu Suk Choi et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

A New Mesenchymal Stem Cell (MSC) Paradigm: Polarization into a Pro-Inflammatory MSC1 or an Immunosuppressive MSC2 Phenotype

(2010) Ruth S. Waterman et al.   PLoS One

Unique multipotent cells in adult human mesenchymal cell populations

(2010) Y. Kuroda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Efficacy of Bone Marrow-Derived Mesenchymal Stem Cells in the Treatment of Sclerodermatous Chronic Graft-versus-Host Disease: Clinical Report

(2009) Hong Zhou et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Bronchiolitis Obliterans Syndrome After Allogeneic Hematopoietic Stem Cell Transplantation—An Increasingly Recognized Manifestation of Chronic Graft-versus-Host Disease

(2009) Jason W. Chien et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

MSCs inhibit monocyte-derived DC maturation and function by selectively interfering with the generation of immature DCs: central role of MSC-derived prostaglandin E2

(2009) G. M. Spaggiari et al.   BLOOD

Mesenchymal Stem Cell Homing: The Devil Is in the Details

(2009) Jeffrey M. Karp et al.   Cell Stem Cell

Single intra-arterial injection of mesenchymal stromal cells for treatment of steroid-refractory acute graft-versus-host disease: a pilot study

(2009) Nobuyoshi Arima et al.   CYTOTHERAPY

Cotransplantation with MSCs improves engraftment of HSCs after autologous intra-bone marrow transplantation in nonhuman primates

(2009) Shigeo Masuda et al.   EXPERIMENTAL HEMATOLOGY

Prolonged ex vivo culture of human bone marrow mesenchymal stem cells influences their supportive activity toward NOD/SCID-repopulating cells and committed progenitor cells of B lymphoid and myeloid lineages

(2009) A. Briquet et al.   HAEMATOLOGICA

Graft-versus-host disease

(2009) James LM Ferrara et al.   LANCET

Repair of Tissues by Adult Stem/Progenitor Cells (MSCs): Controversies, Myths, and Changing Paradigms

(2009) Darwin J Prockop   MOLECULAR THERAPY

Multipotent stromal cells are activated to reduce apoptosis in part by upregulation and secretion of stanniocalcin-1

(2009) Gregory J. Block et al.   STEM CELLS

Infusion of Mesenchymal Stromal Cells can Aid Hematopoietic Recovery Following Allogeneic Hematopoietic Stem Cell Myeloablative Transplant: A Pilot Study

(2009) Nathalie Meuleman et al.   STEM CELLS AND DEVELOPMENT

Mesenchymal stem cells exert differential effects on alloantigen and virus-specific T-cell responses

(2008) H. Karlsson et al.   BLOOD

Transplantation of ex-vivo culture-expanded parental haploidentical mesenchymal stem cells to promote engraftment in pediatric recipients of unrelated donor umbilical cord blood: results of a phase I–II clinical trial

(2008) M L MacMillan et al.   BONE MARROW TRANSPLANTATION

How Do Mesenchymal Stromal Cells Suppress T Cells?

(2008) Armand Keating   Cell Stem Cell

Isolation of functionally distinct mesenchymal stem cell subsets using antibodies against CD56, CD271, and mesenchymal stem cell antigen-1

(2008) V. L. Battula et al.   HAEMATOLOGICA

Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study

(2008) Katarina Le Blanc et al.   LANCET

The correlation between cotransplantation of mesenchymal stem cells and higher recurrence rate in hematologic malignancy patients: outcome of a pilot clinical study

(2008) H Ning et al.   LEUKEMIA

Derivation of Lung Epithelium from Human Cord Blood–derived Mesenchymal Stem Cells

(2007) Viranuj Sueblinvong et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Application of multipotent mesenchymal stromal cells in pediatric patients following allogeneic stem cell transplantation

(2007) Ingo Müller et al.   BLOOD CELLS MOLECULES AND DISEASES

Human Leukocyte Antigen-G5 Secretion by Human Mesenchymal Stem Cells Is Required to Suppress T Lymphocyte and Natural Killer Function and to Induce CD4+CD25highFOXP3+Regulatory T Cells

(2007) Zohair Selmani et al.   STEM CELLS